High Nasal Root: Causes & Reasons

Possible Causes for High Nasal Root

root (broad/high or other), smooth upper vermillion border, thin upper lip vermillion, retrognathia. [gene.sfari.org]

root, thin upper lip, and high palate. [malacards.org]

Abstract We report on a patient presenting with cognitive delay, prenatal and postnatal growth deficiency, microcephaly, ptosis of eyelids, high and broad nasal root, and [doi.org]

Qazi-Markouizos Syndrome

Additional features include narrow and high-arched palate, prominent nasal root, long philtrum, and open mouth with drooling, as well as variably present cryptorchidism, hypertelorism [malacards.org]

Klein-Waardenburg Syndrome

root. [altmeyers.org]

It consists of a white forelock, vitiligo, partial or total heterochromic irides, hyperplastic broad high nasal root, lateral displacement of the medial canthi and lacrimal [whonamedit.com]

More rarely, there is also genuine hypertelorism and hyperplasia of the medial part of the eyebrows as well as hyperplasia of the bony part of the nose with broad, high nasal [altmeyers.org]

Waardenburg Syndrome

Minor criteria include congenital leukoderma, synophrys/medial eyebrow flare, broad/high nasal root with prominent columella and hypoplastic alae nasi. [orpha.net]

nasal root Hypoplasia of alae nasi Prematurely greying hair (predominately white by age 30 years) In 1995, Liu, Newton and Read 5 used the same list to define WS2. [onlinelibrary.wiley.com]

nasal root 52-100% 0-14% medial eyebrow flare 63-70% 7% Type I variable phenotype sesorineural hearing loss congenital, non-progressive, uni- or bilateral most common type [en.wikibooks.org]

Waardenburg Syndrome Type 4C

Minor Criteria: Skin hypopigmentation (congenital leukoderma), synophrys/medial eyebrow flare, broad/high nasal root, prominent columella, hypoplastic alae nasi, premature [preventiongenetics.com]

root. [cureus.com]

Upon a physical examination, the patient had blue homochromatic irises with a normal visual response, coarse hair texture, pallor of nails, and a slightly broad high nasal [cureus.com]

Lujan-Fryns Syndrome

An X-linked recessive mental retardation syndrome (OMIM:309520) characterised by tall stature, hypernasal voice, hyperextensible digits and high nasal root. [medical-dictionary.thefreedictionary.com]

Definition Clinically, Lujan-Fryns syndrome can be distinguished from Opitz-Kaveggia syndrome by tall stature, hypernasal voice, hyperextensible digits and high nasal root [uniprot.org]

Affected individuals also have a long, thin face with distinctive facial features such as a prominent top of the nose (high nasal root); a short space between the nose and [ghr.nlm.nih.gov]

Macrocephaly Type Fryns

Affected individuals also have a long, thin face with distinctive facial features such as a prominent top of the nose (high nasal root); a short space between the nose and [medlineplus.gov]

Waardenburg Syndrome Type 1

The minor criteria are congenital vitiligo, synophrys, broad high nasal root, hypoplasia of alae nasi, and premature graying of hair. [healio.com]

nasal root 52-100% 0-14% medial eyebrow flare 63-70% 7% Type I variable phenotype sesorineural hearing loss congenital, non-progressive, uni- or bilateral most common type [en.wikibooks.org]

nasal root, and dystopia canthorum (increase in the distance between the inner canthi with normal inter-pupillary distance) [1]. [escholarship.org]

Joubert Syndrome Type 21

nasal root, and large ears. [ng.neurology.org]

He exhibited a broad and high forehead, hypertelorism, flat nasal root, thin upper lip, large chin, and broad toes (Figure 2C). He had no apparent oral findings. [ng.neurology.org]

(C) Patient 2 showed craniofacial features similar to those of patient 1: broad and high forehead, hypertelorism, flat nasal root, thin upper lip, and large chin. [ng.neurology.org]

FG Syndrome Type 2

nasal root; high, narrow palate; and short philtrum) (Lujan. [preventiongenetics.com]

[…] is further characterized by a Marfan-like appearance, which include a marfanoid habitus (large head; tall, thin body habitus) and craniofacial changes (long, thin face; high [preventiongenetics.com]

Waardenburg Syndrome Type 2B

No other associated abnormalities (such as hair or skin hypopigmentation, medial eyebrow flare, broad and high nasal root, hypoplasia of alae nasi, or premature greying of [bjo.bmj.com]

Mosaic Trisomy 14

[…] bridge Elevated nasal bridge High nasal bridge Prominent bridge of nose Prominent nasal root Protruding bridge of nose Protruding nasal bridge [ more ] 0000426 Short neck [rarediseases.info.nih.gov]

Mental retardation Mental retardation, nonspecific Mental-retardation [ more ] 0001249 Micrognathia Little lower jaw Small jaw Small lower jaw [ more ] 0000347 Prominent nasal [rarediseases.info.nih.gov]

Waardenburg Syndrome Type 2

The minor criteria are congenital vitiligo, synophrys, broad high nasal root, hypoplasia of alae nasi, and premature graying of hair. [healio.com]

nasal root 52-100% 0-14% medial eyebrow flare 63-70% 7% Type I variable phenotype sesorineural hearing loss congenital, non-progressive, uni- or bilateral most common type [en.wikibooks.org]

nasal root, prominent columella Hypoplastic alae nasi Premature gray hair (age Type I Waardenburg syndrome is characterized by evidence of dystopia canthorum and the full [centogene.com]

14q32 Duplication Syndrome

The patients had moderate intellectual disability, a high forehead, a broad nasal root, downslanting palpebral fissures, epicanthal folds, retrognathia, hypertelorism, wrinkled [unboundmedicine.com]

X-linked Mental Retardation Type Cabezas

[…] bridge Flat, nasal bridge Flattened nasal bridge Low nasal bridge Low nasal root [ more ] 0005280 Generalized hypotonia Decreased muscle tone Low muscle tone [ more ] 0001290 [rarediseases.info.nih.gov]

High forehead 0000348 Hypospadias 0000047 Intellectual disability Mental deficiency Mental retardation Mental retardation, nonspecific Mental-retardation [ more ] 0001249 [rarediseases.info.nih.gov]

Delayed puberty Delayed pubertal development Delayed pubertal growth Pubertal delay [ more ] 0000823 Depressed nasal bridge Depressed bridge of nose Flat bridge of nose Flat nasal [rarediseases.info.nih.gov]

Joubert Syndrome Type 8

nasal root, and large ears. [ng.neurology.org]

He exhibited a broad and high forehead, hypertelorism, flat nasal root, thin upper lip, large chin, and broad toes (Figure 2C). He had no apparent oral findings. [ng.neurology.org]

(C) Patient 2 showed craniofacial features similar to those of patient 1: broad and high forehead, hypertelorism, flat nasal root, thin upper lip, and large chin. [ng.neurology.org]

Waardenburg Syndrome Type 2D

Minor Criteria : Skin hypopigmentation (congenital leukoderma), synophrys/medial eyebrow flare, broad/high nasal root, prominent columella, hypoplastic alae nasi, premature [preventiongenetics.com]

Other features include high and broad nasal root and also nasi hypoplasia. A squared jaw is reported in some patients. [owlapps.net]

Partial Trisomy 1q

nasal root, hypoplastic alae nasi, high-arched palate, maxillary projection, narrow hands, a short fourth right metatarsus, scoliosis, and genu valgum. [karger.com]

3rd-10th centile), low weight (41.4 kg, <3rd centile), normal head circumference (52,5 cm; 2nd-50th centile), prominent metopic suture, facial asymmetry, long eyelashes, high [karger.com]

Waardenburg Syndrome Type 4A

The general manifestations included hearing loss (1/5), broad high nasal root (2/5) and hypoplasia of alae nasi (2/5). [spandidos-publications.com]

root. [cureus.com]

As listed in Table II, the general manifestations included hearing loss (1/5), broad high nasal root (1/5) and hypoplasia of alae nasi (1/5). [spandidos-publications.com]

Blepharophimosis - Intellectual Disability Syndrome Type Verloes

root. [uniprot.org]

nasal root High narrow palate Dental crowding Maxillary hypoplasia Micrognathia/retrognathia Open mouth Frontal hair upsweep Small ears HandLong hyperextensible digits Broad [docslide.com.br]

Disease description Clinically, Lujan-Fryns syndrome can be distinguished from Opitz-Kaveggia syndrome by tall stature, hypernasal voice, hyperextensible digits and high nasal [uniprot.org]

Joubert Syndrome Type 13

nasal root, and large ears. [ng.neurology.org]

He exhibited a broad and high forehead, hypertelorism, flat nasal root, thin upper lip, large chin, and broad toes (Figure 2C). He had no apparent oral findings. [ng.neurology.org]

(C) Patient 2 showed craniofacial features similar to those of patient 1: broad and high forehead, hypertelorism, flat nasal root, thin upper lip, and large chin. [ng.neurology.org]

FG Syndrome Type 3

nasal root; high, narrow palate; and short philtrum) (Lujan. [preventiongenetics.com]

Trisomy 19p

Dysmorphic facies consisted of coarse hair with a high frontal hairline, short philtrum and nose, flat nasal root, and a broad mouth with downturned commissures. [link.springer.com]

Both routine G-banded and high-resolution prometaphase chromosome studies were employed in evaluation of the family. [link.springer.com]

FG Syndrome Type 5

nasal root; high, narrow palate; and short philtrum) (Lujan. [preventiongenetics.com]

Waardenburg Syndrome Type 4B

root. [cureus.com]

[…] bridge Elevated nasal bridge High nasal bridge Prominent bridge of nose Prominent nasal root Protruding bridge of nose Protruding nasal bridge [ more ] 0000426 Synophrys [rarediseases.info.nih.gov]

Upon a physical examination, the patient had blue homochromatic irises with a normal visual response, coarse hair texture, pallor of nails, and a slightly broad high nasal [cureus.com]

Hirschsprung Disease - Deafness - Polydactyly Syndrome

nasal root Hypoplastic alae nasi Premature grey hair (before age 30 years) WS is associated with neural crest-derived melanocyte deficiency caused by mutations in transcription [neoreviews.aappublications.org]

Type I WS includes the following primary features: Lateral displacement of the medial canthi and lacrimal puncta (100%) Hyperplastic high nasal root (75%) Hyperplasia of the [emedicine.medscape.com]

[…] calculate the W index in mm are: inner canthal distance (a), interpupillary distance (b), and outer canthal distance (c) Minor Criteria Skin hypopigmentation Synophyrys Broad/high [neoreviews.aappublications.org]

Woronets Trait

W Waardenburg's syndrome TYPE I, hearing loss; dystopia canthorum, high nasal root, heterochromia irides, white forelock, early graying; from mutation in PAX3 gene, transcription [wikem.org]

Gupta Patton Syndrome

nasal root). [e-fjs.org]

nasal root as seen in [Figure 1] and [Figure 2]. [e-fjs.org]

Keywords: Blue eyes, broad high nasal root, Hirschsprung's disease, Shah-Waardenburg syndrome, total colonic aganglionosis, white forelock How to cite this article: Gupta [e-fjs.org]

Waardenburg Syndrome Type 2C

No other associated abnormalities (such as hair or skin hypopigmentation, medial eyebrow flare, broad and high nasal root, hypoplasia of alae nasi, or premature greying of [bjo.bmj.com]

FG Syndrome Type 4

nasal root; high, narrow palate; and short philtrum) (Lujan. [preventiongenetics.com]