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43 Possible Causes for High Pain Threshold, Sensation Disorder

  • Syringomyelia

    If not treated surgically, syringomyelia often leads to progressive weakness in the arms and legs, loss of hand sensation, and chronic, severe pain.[ninds.nih.gov] Symptoms include atrophy of the tongue, difficulty in swallowing ( dysphagia ), loss of pain and temperature sensation in the face, and a variety of other neurological disorders[britannica.com] In most cases, the disorder is related to a congenital abnormality of the brain called a Chiari malformation, which causes brain tissue to protrude from its normal location[ninds.nih.gov]

  • Peripheral Neuropathy

    This can inhibit sensation and movement as well as organ function, or cause a variety of other disorders, based on the type of nerve affected.[neuravite.com] Usually, the disorder affects the nerves that provide sensation, which causes pain , tingling, and burning symptoms of the nerves affected.[medicinenet.com] Peripheral neuropathy is disorder of nerve(s) apart from the brain and spinal cord.[medicinenet.com]

  • Congenital Pain Insensitivity

    .: 91 988 657 3382; E-mail: [email protected] Abstract: Congenital pain insensitivity and anhidrosis is an extremely rare disorder characterized by lack of pain sensation[content.iospress.com] These high threshold stimuli are detected by specialised peripheral sensory neurons known as nociceptors which are abundant in the Peripheral Pain Pathway.[neurosciencefundamentals.unsw.wikispaces.net] CIPA, an autosomal recessive disorder presents with congenital lack of pain sensation, inability to sweat, episodes of recurrent hyperpyrexia, mental retardation and self-mutilation[e-ijd.org]

  • Diabetic Peripheral Neuropathy

    It is a progressive disorder that results in a gradual decrease in peripheral sensation and eventually complete loss of sensation.[ncbi.nlm.nih.gov] We propose in this study to examine whether sensory testing to determine mechanical pain threshold [MPT] or heat pain threshold [HPT] will predict the subject's response to[clinicaltrials.gov] Diabetic nerve pain symptoms can include: Prickling or tingling feelings A burning sensation Sharp, stabbing or shooting pains in the aforementioned areas.[diabetes.co.uk]

  • Phencyclidine Intoxication

    PCP can cause effects that mimic the full range of symptoms of schizophrenia, such as delusions, paranoia, disordered thinking, a sensation of distance from one's environment[usmleforum.com] High doses can also cause effects similar to symptoms of schizophrenia, such as delusions, paranoia, disordered thinking, a sensation of distance from one’s environment, and[drugfree.org] PCP can cause effects that mimic the full range of symptoms of schizophrenia, such as delusions, paranoia, disordered thinking, sensation of distance from one's environment[lycaeum.org]

  • Opiate

    We used demographic, personality (trait impulsivity, trait psychopathy, aggression, sensation seeking), psychiatric (attention deficit hyperactivity disorder, conduct disorder[ncbi.nlm.nih.gov]

  • Alcohol Hallucinosis

    ., is a neurological disorder characterized by uncomfortable sensations—creeping, pulling, tugging, fidgeting, burning, even aching pain—deep inside the legs, often at night[berkeleywellness.com] Inflammation and fatty infiltration of the liver are common, as are disorders of the gastrointestinal tract ( gastritis , duodenal ulcer , and, less often, severe pancreatitis[britannica.com] Wernicke-Korsakoff syndrome: Wernicke-Korsakoff syndrome is a brain disorder tied to alcoholism.[healthline.com]

  • Leprosy

    "Leprosy may masquerade as various other skin disorders, given its range of symptoms.[telegraph.co.uk] […] should be mindful of if they encounter patients, especially those originally from endemic countries, with persistent or unexplained lesions, changes to skin pigmentation and sensation[telegraph.co.uk]

  • Drug-induced Delirium

    There is confusion, disorientation, restlessness, trembling, fearfulness, DELUSION and disorder of sensation ( HALLUCINATION ).[medical-dictionary.thefreedictionary.com] [L. fr. deliro, to be crazy] delirium A mental disturbance from disorder of brain function caused by high fever, head injury, drug intoxication, drug overdosage or drug withdrawal[medical-dictionary.thefreedictionary.com]

  • Overdose

    This may be manifest as numbness of the extremities, paraesthesia ("pins and needles" sensations), weakness of the limbs, or wasting of the muscles and loss of deep tendon[who.int] Neuroleptics have low abuse potential (see abuse of non-dependence-producing substances). neuropathy, peripheral Disorder and functional disturbance of the peripheral nerves[who.int]

Further symptoms