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1,487 Possible Causes for High Pitched Voice, Malocclusion, Wide Space Between the First and Second Toe

  • Dubowitz Syndrome

    Significant clinical correlation includes: smaU stature, microcephaly, abnormal ears, ptosis, hypertelorism, wide nasal bridge, dental malocclusion, eczema, and mental retardation[healio.com] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] Speech delays, an unusually soft, high-pitched voice, submucous cleft palate, and velopharyngeal insufficiency were noted in childhood.[ncbi.nlm.nih.gov]

  • Seckel Syndrome

    Dental findings include hypodontia, enamel hypoplasia, crowding, and Class II malocclusion.[ncbi.nlm.nih.gov] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] She also displayed high-pitched voice. The age of menarche was 15 years. She had regular menstrual cycles.[termedia.pl]

  • Down Syndrome

    Dental malocclusion and macroglossia are associated. Technical modifications to increase macroglossia surgery safety and efficacy have been described.[doi.org] A wide space, often with a deep fissure between the first and second toes, is also common.[dx.doi.org] Other common oral manifestations of Down syndrome include enlarged hypotonic tongue, crusted and hypotonic lips, mouth breathing, narrow palate with crowded teeth, class III malocclusion[en.wikipedia.org]

    Missing: High Pitched Voice
  • Seckel Syndrome Type 2

    0010230 Cryptorchidism Undescended testes Undescended testis [ more ] 0000028 Dental crowding Crowded teeth Dental overcrowding Overcrowding of teeth [ more ] 0000678 Dental malocclusion[rarediseases.info.nih.gov] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] pitched voice 0001620 Percent of people who have these symptoms is not available through HPO 11 pairs of ribs 0000878 Abnormal finger flexion creases 0006143 Abnormality[rarediseases.info.nih.gov]

  • Bloom Syndrome

    […] fissures, a protruding beaked nose with columella below alae nasi, dysplastic and low-set ears, an arched palate, mild micrognathia, dental anomalies (altered conformation, malocclusion[ijponline.biomedcentral.com] Bloom syndrome listen (… SIN-drome) A rare, inherited disorder marked by height that is shorter than average, a narrow face with redness and a rash, a high-pitched voice,[cancer.gov] People with Bloom syndrome are much smaller than average, and often have a high-pitched voice and characteristic facial features including a long, narrow face; small lower[hon.ch]

    Missing: Wide Space Between the First and Second Toe
  • Laron Syndrome with Immunodeficiency

    […] forehead - Hypertelorism - Hypoplastic maxillary bones / zygomatic bones / maxillary hypoplasia - Macrocephaly / macrocrania / megalocephaly / megacephaly Frequent - Dental malocclusion[csbg.cnb.csic.es] Patients may have a high-pitched voice and present truncal obesity.[symptoma.com] [Eyes]; Protuberant eyes; Blue sclerae; Downslanting palpebral fissures; Corneal diameter, normal; [Mouth]; High palate; Bifid uvula; [Teeth]; Delayed eruption of teeth; Malocclusion[findzebra.com]

    Missing: Wide Space Between the First and Second Toe
  • Congenital Muscular Dystrophy

    One previous study has also shown a high prevalence of open bite and delayed dentition in primary muscle disease. 23 Why malocclusion has developed in our series of children[adc.bmj.com] […] been shown to cause abnormal mandibular growth and an open bite. 24 It is also possible that the facial muscle weakness influences jaw growth in childhood, resulting in malocclusion[adc.bmj.com]

    Missing: Wide Space Between the First and Second Toe
  • Russell-Silver Syndrome

    Though orthodontic treatment may be performed for the malocclusion caused by growth disturbance and right - left asymmetry of viscerocranium, cleft palate is rarely complicated[ci.nii.ac.jp] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] […] palate · small, crowded teeth · low-set, posteriorly rotated &/or prominent ears · unusually, high-pitched voice in early years · clinodactly (inward curving) of the 5th[coltongeorge.com]

  • Baraitser Syndrome

    […] amenorrhea Hand polydactyly Ventricular hypertrophy Abnormal palate morphology Pancytopenia Low posterior hairline Bone marrow hypocellularity Amenorrhea Retinal dysplasia Dental malocclusion[mendelian.co] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] Wide space between first and second toes Wide-spaced big toe Widely spaced 1st-2nd toes Widely spaced first and second toes Widened gap 1st-2nd toes Widened gap first and[rarediseases.info.nih.gov]

  • Tonsillitis

    Some orthodontists believe that chronic mouth breathing from large tonsils and adenoids causes improper alignment of the teeth (malocclusion).[web.archive.org] This may sometimes cause the teeth to become badly aligned (malocclusion).[health24.com] Mood changes Excessive sleepiness Heart problems Some orthodontists believe chronic mouth breathing from large tonsils and adenoids causes improper alignment of the teeth (malocclusion[medicinenet.com]

    Missing: High Pitched Voice Wide Space Between the First and Second Toe

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