Possible Causes for hilar adenopathy Non-Hodgkin Lymphoma Involvement of hilar and mediastinal lymph nodes is less common than in HL. [web.archive.org] Mediastinal adenopathy, however, is a prominent feature of lymphoblastic lymphoma and primary mediastinal B-cell lymphoma, entities primarily found in young adults. [web.archive.org] Erythema Nodosum Hilar adenopathy is associated with the above signs in some cases but has not been recognized generally as an accompaniment of the condition. [annals.org] (in Europe), mycoplasma, chlamydia, histoplasmosis, coccidioidomycosis, mycobacteria Sarcoidosis (11 to 25 percent) with bilateral hilar adenopathy Drugs (3 to 10 percent) [aafp.org] Three cases of erythema nodosum in which hilar adenopathy was a feature were encountered at the Mayo Clinic in a period of four months, and in each FULL TEXT [annals.org] Sarcoidosis adenopathy. [ncbi.nlm.nih.gov] Further investigation revealed hilar adenopathy consistent with sarcoidosis. The patient responded well to topical corticosteroids. [ncbi.nlm.nih.gov] adenopathy Dry cough Dyspnoe A combination of the first four symptoms is often described as Löfgren syndrome. [flexikon.doccheck.com] Bronchogenic Carcinoma § Hilar mass § Small or invisible lung nodule o High metastatic potential o Rapid growth o May be associated with § Hypoglycemia § Cushing's syndrome § Inappropriate secretion [learningradiology.com] […] peripheral nodule o Found in scars o Solitary pulmonary nodule (52%) o Upper lobe distribution (69%) · Small cell undifferentiated Oat Cell Carcinoma o Appearances § Mediastinal adenopathy [learningradiology.com] Recurrent Small-Cell Carcinoma of the Lung Radiograph and computed tomography (CT) images of SCLC typically show a large hilar mass with mediastinal adenopathy. [breathe.ersjournals.com] Small-Cell Carcinoma of the Lung Radiograph and computed tomography (CT) images of SCLC typically show a large hilar mass with mediastinal adenopathy. [breathe.ersjournals.com] Pulmonary Sarcoidosis Results of radiographs and a computed tomography scan of the chest revealed multiple pulmonary nodules with mediastinal and hilar adenopathy. [ncbi.nlm.nih.gov] The patient was a 41-year-old man presenting with stage I pulmonary sarcoidosis (hilar adenopathy), which had progressed to stage II (pulmonary infiltrates) 19 months later [ncbi.nlm.nih.gov] Löfgren syndrome Löfgren syndrome manifests as a triad of acute polyarthritis, erythema nodosum, and hilar adenopathy. [merckmanuals.com] Mycoplasma Pneumonia A chest X-ray was negative for pneumonia and hilar adenopathy. [hindawi.com] Radiographic findings Most frequently: interstitial infiltrates with predilection for lower lobes, commonly with hilar adenopathy Occasionally presents with a lobar pneumonia [pedclerk.bsd.uchicago.edu] Consolidated pneumonia, large effusions, and hilar adenopathy are uncommonly reported, and severe disease has been described in certain patient populations, including those [mdedge.com] Pulmonary Tuberculosis For example, they may present with hilar adenopathy or lower-lobe infiltrates. 5 Are there clinical prediction rules for tuberculosis? [mdedge.com] In primary tuberculosis the process is generally seen as a middle or lower lung zone infiltrate, often with associated ipsilateral hilar adenopathy. [southsudanmedicaljournal.com] […] or mediastinal adenopathy at any age should strongly suggest TB Lymph node § Mostly unilateral hilar and/or paratracheal, usually right sided, rarely bilateral § Differentiates [learningradiology.com] Pulmonary Cavitary Tuberculosis Chest x-ray showing bilateral hilar adenopathy of primary pulmonary TB 6. [en.wikipedia.org] […] or mediastinal adenopathy at any age should strongly suggest TB Lymph node § Mostly unilateral hilar and/or paratracheal, usually right sided, rarely bilateral § Differentiates [learningradiology.com] Mediastinal or hilar adenopathy can also be the sole manifestation of tuberculosis, particularly in patients with compromised immune systems. [clinicaladvisor.com] Cystic Fibrosis Subsequent changes include areas of infiltrate, atelectasis, and hilar adenopathy. [merckmanuals.com] Hodgkin Lymphoma […] or mediastinal adenopathy Most common manifestation Present in 90-99% Commonly multiple lymph node groups involved Anterior mediastinal and retrosternal nodes commonly involved [learningradiology.com] adenopathy is usually bilateral but asymmetric Anterior mediastinal nodes commonly involved They may calcify after radiation therapy Staging (Ann Arbor) Stage I is adenopathy [learningradiology.com] Hodgkin lymphoma Rarely, hemoptysis Rarely, back or bone pain Imaging Findings Parenchymal lung involvement occurs in 1/3 of patients with Hodgkin Almost all have associated hilar [learningradiology.com] Transient Sarcoidosis Kviem-Siltzbach test (90% with hilar adenopathy). 41. [slideshare.net] Stage 1 is hilar adenopathy alone (Fig. 13-2), often with right paratracheal involvement. [what-when-how.com] Löfgren's syndrome (especially in Caucasians): erythema nodosum, fever, arthralgias, and radiographic evidence of bilateral hilar adenopathy - likely Sarcoidosis (ref Parrish [medicine.uiowa.edu] Pulmonary Lymphoma Diagnostic criteria were: (1) histologically proven lymphomatous pulmonary involvement; (2) absence of mediastinal and/or hilar adenopathy on chest radiography; (3) absence [ncbi.nlm.nih.gov] […] or mediastinal adenopathy Most common manifestation Present in 90-99% Commonly multiple lymph node groups involved Anterior mediastinal and retrosternal nodes commonly involved [learningradiology.com] adenopathy 1 4 5 (20.8%) Chest wall invasion 0 1 1 (4.2%) Diagnostic procedures Percutaneous biopsy 1 1 2 (8.3%) Bronchoscopy 10 10 20 Biopsy 1 3 4 (16.7%) TBLB 1 1 2 (8.3% [academic.oup.com] Berylliosis Hilar adenopathy, linear scars, lung distortion, bullae, and pleural thickening were found less commonly. [ncbi.nlm.nih.gov] Acute Sarcoidosis hilar adenopathy and parenchymal involvement (reticular opacities) Stage III - Parenchymal involvement (reticular opacities) with shrinking adenopathy Stage IV - Parenchymal [emedicine.medscape.com] Stages of sarcoidosis, as identified through imaging, are as follows (see also the images below): Stage O - No findings Stage I - Bilateral hilar adenopathy Stage II - Bilateral [emedicine.medscape.com] […] or paratracheal adenopathy and joint involvement (EN is associated with a good prognosis) Subcutaneous nodules Ocular lesions Ocular involvement is the presenting symptom [emedicine.medscape.com] Silicosis adenopathy and, later, early massive fibrosis. [ncbi.nlm.nih.gov] Hilar and mediastinal adenopathy (hi) can develop associated in some cases with eggshell calcifications (eg). This can precede the development of micronodules. [web.archive.org] […] together in an environment with high concentrations of quartz pursued very different clinical courses; one died of rapidly progressive silicosis and the other developed hilar [ncbi.nlm.nih.gov] Mediastinal Neoplasm A case of giant cell tumor of the thoracic spine simulating mediastinal neoplasm was identified on plain films, CT scans, MR images, and with scintigraphy. CT showed a hypervascular soft-tissue mass with shell-like calcification in the right upper mediastinum. MR imaging showed a collapse of the T1 vertebral body and a[…] [ncbi.nlm.nih.gov] Silicotuberculosis Hilar and mediastinal adenopathy (hi) can develop associated in some cases with eggshell calcifications (eg). This can precede the development of micronodules. [web.archive.org] This entity is associated with medial upper lung zone consolidated opacities, some with air bronchograms, can have symmetric hilar and mediastinal adenopathy, volume loss [web.archive.org] Amyloidosis Systemic light chain amyloidosis (AL) is a life-threatening disease caused by aggregation and deposition of monoclonal immunoglobulin light chains (LC) in target organs. Severity of heart involvement is the most important factor determining prognosis. Here, we report the 4.0 Å resolution cryo-electron microscopy map[…] [ncbi.nlm.nih.gov] Systemic Amyloidosis Int J Biol Macromol. 2017 Jun;99:630-640. doi: 10.1016/j.ijbiomac.2017.03.028. Epub 2017 Mar 7. Author information 1 Interdisciplinary Biotechnology Unit, Aligarh Muslim University, Aligarh 202002, India. 2 Molecular Science Lab, National Institute of Immunology, New Delhi 110067, India. 3 Department of Pharmaceutical Chemistry,[…] [ncbi.nlm.nih.gov] Pneumoconiosis Radiographs revealed multiple bilateral pulmonary nodules associated with hilar and mediastinal adenopathy. [ncbi.nlm.nih.gov] Uveoparotid Fever Other clinical features may include hilar adenopathy, generalized lymphadenopathy, visceral lesion and skin rash. [whonamedit.com] A chest radiograph suggested bilateral hilar adenopathy and possible right paratracheal adenopathy but was otherwise unremarkable. [nejm.org] adenopathy paratracheal adenopathy may be noted CT of the head Management glucocorticoid prednisone 60 mg QD (case report) [3] enlargement with uniform contrast enhancement [anvita.info] Superior Vena Cava Syndrome [Article in English, Portuguese] Abstract The superior vena cava syndrome represents the set of signs and symptoms resulting from obstruction of superior vena cava. The syndrome has as main causes malignant tumors such as bronchogenic carcinoma, lymphoma and mediastinal metastases. Lung cancer accounts for[…] [ncbi.nlm.nih.gov] Mycoplasma Infection This report describes a patient with psychosis due to a Mycoplasma pneumoniae infection. Although he received specific treatment for this infection, the diagnosis was only confirmed after clinical recovery. The neuropsychiatric complications of mycoplasma infection are discussed. [ncbi.nlm.nih.gov] Acute Berylliosis Findings in chronic berylliosis include reticulonodular infiltrates, hilar adenopathy, and large coalescent infiltrates in both lungs. [medical-clinic.org] CXR: - Stage 0 Clear - Stage I Bilateral hilar adenopathy - Stage II Hilar adenopathy and parenchymal infiltrates - Stage III Parenchymal infiltrates only - State IV Extensive [lumen.luc.edu] Hilar adenopathy, noted in 30% to 40% of patients, is usually mild, bilateral, and associated with parenchymal infiltrates. [nap.edu] Chronic Pulmonary Coccidioidomycosis Hilar adenopathy Hilar adenopathy is seen in approximately 20-25% of patients with coccidioidomycosis. It is usually unilateral and concomitant with parenchymal lesions. [emedicine.medscape.com] Diagnostic Test Results-Imaging Chest X-ray shows bilateral diffuse infiltrates, nodules, mediastinal or hilar adenopathy, or pleural effusion. [quizlet.com] Radiographic hints, when present, include a thin-walled cavity, nodule formation at sites of infiltrates, and pronounced hilar adenopathy, but these findings are nonspecific [oncohemakey.com] Pulmonary Fungal Infection • Massive inhalation of organisms: – May show fairly discrete, nodular opacities 3-4 mm in diameter with hilar adenopathy 11. [slideshare.net] Radiographic findings may be unremarkable in up to 1/2 of patients or show lobar infiltrate and ipsilateral hilar adenopathy. [clinicaladvisor.com] Hilar or mediastinal adenopathy also develop in those with fungal infection. [symptoma.com] Anthracosilicosis Abstract The authors reexamined 300 autopsies which were carried out from 1965 to 1983, on male subjects affected by pulmonary anthracosilicosis already diagnosed in vita and holders of pensions for invalidity allocated to them by the Istituto Nazionale Assicurazione Infortuni sul Lavoro. Their livers were[…] [ncbi.nlm.nih.gov] Granulomatous Lung Disease Radiographic stages of sarcoidosis -Stage 1: bilateral hilar adenopathy, mediastinal adenopathy -Stage 2: adenopathy and parenchymal lung disease -Stage 3: parenchymal lung [brainscape.com] Radiographs or computed tomography of the chest showed single or multiple nodular lesions in 10 cases and hilar adenopathies in 1 case. [ncbi.nlm.nih.gov] […] disease only -Stage 4: fibrosis and cystic changes -Bilateral hilar adenopathy most common finding -Upper and mid lung shows coarse reticular and cystic changes and volume [brainscape.com]
