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155 Possible Causes for Hilar Adenopathy, Hypercalcemia

  • Sarcoidosis

    A blood analysis revealed hypercalcemia. Computed tomography revealed mediastinal and hilar lymph node hyperplasia.[] RATIONALE: The usual presentation of sarcoidosis is hilar adenopathy, pulmonary reticular opacities, skin, joint, or eye lesions.[] The adenopathy may be unilateral or bilateral hilar and/or right paratracheal lymphadenopathy.[]

  • Bronchogenic Carcinoma

    Hypercalcemia of malignancy is the most common cause of hypercalcemia in hospitalized patients.[] § Hilar mass § Small or invisible lung nodule o High metastatic potential o Rapid growth o May be associated with § Hypoglycemia § Cushing's syndrome § Inappropriate secretion[] For instance, Hypercalcemia is more common with squamous cell carcinoma due to ectopic secretion of the parathyroid hormone related peptide (PTHrP).[]

  • Hodgkin's Disease

    This increase in blood calcium, or hypercalcemia, causes subtle signs that are important for both Hodgkin's survivors and their families to recognize.[] […] or mediastinal adenopathy Most common manifestation Present in 90-99% Commonly multiple lymph node groups involved Anterior mediastinal and retrosternal nodes commonly involved[] But lethargy and sadness can be mistaken for depression, and confusion can be written off as forgetfulness or distraction, when these are additional signs of hypercalcemia[]

  • Non-Hodgkin Lymphoma

    Other features include anemia; hypercalcemia; and renal insufficiency. A malignant neoplasm of the bone marrow composed of plasma cells.[] Involvement of hilar and mediastinal lymph nodes is less common than in HL.[] A bone marrow-based plasma cell neoplasm characterized by a serum monoclonal protein and skeletal destruction with osteolytic lesions, pathological fractures, bone pain, hypercalcemia[]

  • Pulmonary Tuberculosis

    For example, they may present with hilar adenopathy or lower-lobe infiltrates. 5 Are there clinical prediction rules for tuberculosis?[] In primary tuberculosis the process is generally seen as a middle or lower lung zone infiltrate, often with associated ipsilateral hilar adenopathy.[] […] or mediastinal adenopathy at any age should strongly suggest TB Lymph node § Mostly unilateral hilar and/or paratracheal, usually right sided, rarely bilateral § Differentiates[]

  • Multidrug-resistant Tuberculosis

    BACKGROUND: Multidrug resistant (MDR) tuberculosis (TB) represents TB which is simultaneous resistant to at least rifampicin (R) and isoniazid (H). Identifying inadequate therapy as the main cause of this form of the disease and explaining the factors leading to its occurrence, numerous social determinants that[…][]

  • Pulmonary Sarcoidosis

    Hypercalcemia may occur because of increased conversion of vitamin D to the activated form by activated macrophages.[] Results of radiographs and a computed tomography scan of the chest revealed multiple pulmonary nodules with mediastinal and hilar adenopathy.[] The patient was a 41-year-old man presenting with stage I pulmonary sarcoidosis (hilar adenopathy), which had progressed to stage II (pulmonary infiltrates) 19 months later[]

  • Transient Sarcoidosis

    Intermittent hypercalcemia – 17-19%. 34.[] 2009) macrophages in patients with sarcoidosis are capable of the hydroxylation that produces the active metabolite of vitamin D which is the likely causative factor for hypercalcemia[] Stage 1 is hilar adenopathy alone (Fig. 13-2), often with right paratracheal involvement.[]

  • Gastrointestinal Sarcoidosis

    Sharma OP: Hypercalcemia in granulomatous disorders: a clinical review. Curr Opin Pulm Med 2000;6:442-447.[] adenopathy stage 2 bilateral hilar adenopathy with parenchymal infiltrates stage 3 diffuse parenchymal infiltrates in the absence of hilar adenopathy stage 4 pulmonary fibrosis[] The patient required hemodialysis for hypercalcemia and renal failure. Repeat ACE level was 95 U/L.[]

  • Hepatic Sarcoidosis

    We report a case of early recurrence of sarcoidosis in the liver allograft diagnosed on biopsy in a patient who presented with severe hypercalcemia, kidney dysfunction, and[] Their patients with NSG lacked extra-thoracic involvement, had normal serum ACE levels, and only a few had hilar adenopathy. 9 Churg et al concluded that NSG was a histologic[] However a moderately increased Serum Angiotensin Converting Enzyme and hypercalcemia were present.[]

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