Possible Causes for hilar lymphadenopathy Sarcoidosis It can present with bilateral hilar lymphadenopathy, skin lesions, eye involvement and locomotor system findings. [ncbi.nlm.nih.gov] The disease most frequently manifests with bilateral hilar lymphadenopathy and infiltrations in the lungs and skin, as well as with eye lesions. [ncbi.nlm.nih.gov] Sarcoidosis can affect all individuals with any race, sex, or age but commonly affects young- and middle-aged adults and usually presents with bilateral hilar lymphadenopathy [ncbi.nlm.nih.gov] Transient Sarcoidosis Stage II: bilateral hilar lymphadenopathy with pulmonary infiltrates. Stage III: pulmonary infiltrates without hilar adenopathy. [slideshare.net] The chest computed tomography (CT) scan revealed bilateral hilar lymphadenopathy. A mediastinal lymph node biopsy showed noncaseating giant epithelioid cell granulomas. [care.diabetesjournals.org] He was also found to have hilar lymphadenopathy. [ijem.in] Pulmonary Sarcoidosis Further evaluation revealed a large left lower lobe mass and hilar lymphadenopathy. [ncbi.nlm.nih.gov] We report an 11 yr old girl who presented with chronic cough, low grade fever, recent exposure to tuberculosis and hilar lymphadenopathy. [ncbi.nlm.nih.gov] After 6 more months, prominent bilateral hilar lymphadenopathy and highly elevated serum angiotensin-converting enzyme confirmed the diagnosis of pulmonary sarcoidosis. [ncbi.nlm.nih.gov] Erythema Nodosum It is defined as having an acute onset with bilateral hilar lymphadenopathy (BHL), fever, erythema nodosum (EN) and/or arthritis. [ncbi.nlm.nih.gov] lymphadenopathy, fever, arthritis, and uveitis, which has been termed Löfgren syndrome. [emedicine.medscape.com] The most common cutaneous manifestation of sarcoidosis is erythema nodosum. [16] A characteristic form of acute sarcoidosis involves the association of erythema nodosum, hilar [emedicine.medscape.com] Acute Sarcoidosis […] opacities without hilar lymphadenopathy Stage IV Lung fibrosis * In most cases, the disease resolves spontaneously at this stage. [amboss.com] Enlarged lymph nodes are found in hilar and peripheral locations, such as cervical, axillary, and inguinal. [emedicine.medscape.com] An x-ray may show parenchymal disease with bilateral hilar lymphadenopathy, but these features are not always evident. A biopsy is the gold standard for diagnosis. [amboss.com] Hereditary Angioedema Hereditary angioedema (HAE) is a rare genetic disorder that causes a deficiency in or dysfunction of C1 esterase inhibitor (C1-INH) and is clinically characterized by sudden and recurrent attacks of angioedema. Although almost any part of the body can be affected, HAE is of greatest concern and can be[…] [ncbi.nlm.nih.gov] Uveoparotid Fever The chest radiograph (Figure 2) showed the presence of bilateral hilar lymphadenopathy. [nzma.org.nz] She had been previously diagnosed with uveitis and bilateral hilar lymphadenopathy. [hindawi.com] Computed tomography (CT) of the chest showed hilar lymphadenopathy with bibasilar interstitial lung disease. [ncbi.nlm.nih.gov] Pulmonary Actinomycosis Computed tomogram shows right hilar lymphadenopathy and a broncholith obstructing the bronchus intermedius. Fig. 2. [rc.rcjournal.com] and/or mediastinal lymphadenopathy Treatment and prognosis A commonly accepted principal treatment of actinomycosis comprises of long-term administration of a high-dose [radiopaedia.org] Additional, yet non-specific findings comprise hilar or mediastinal lymphadenopathy, bronchiectasis within the consolidated area, pleural thickening and pleural effusion. [symptoma.com] Middle Lobe Syndrome Aetiology Thymoma, hilar lymphadenopathy (e.g., TB, sarcoidosis or lymphoma), tumours or obstruction (due to intraluminal tumours or foreign bodies). [medical-dictionary.thefreedictionary.com] Bronchial obstruction can result from extrinsic compression as in hilar lymphadenopathy or tumor of neoplastic origin; however, atelectasis in children usually results from [emedicine.medscape.com] Obstructive MLS is usually caused by endobronchial lesions or extrinsic compression of the middle lobe bronchus such as from hilar lymphadenopathy or tumors of neoplastic [ncbi.nlm.nih.gov] Histoplasmosis Figure 2: Chest CT showing right hilar lymphadenopathy (2.5 Figure 4 cm). [mycology.imedpub.com] In normal adults there is peripheral pulmonary lesion associated with hilar lymphadenopathy resembling Ghon's complex of tuberculosis. [histopathology-india.net] Mediastinal and hilar lymphadenopathy may or may not be present. [doi.org] Gastrointestinal Sarcoidosis Furthermore, bilateral hilar lymphadenopathy was observed on chest radiography, leading to a diagnosis of pulmonary sarcoidosis. [synapse.koreamed.org] Sarcoid lesions in GIS can exist together with hilar lymphadenopathy and/or disseminated lesions, or may be seen before or after them [7-9]. [peertechz.com] In the majority of cases, the patient was either previously diagnosed with pulmonary sarcoidosis or had bilateral hilar lymphadenopathy, which is typical of sarcoidosis. [synapse.koreamed.org] Viral Lower Respiratory Infection Pleural effusion, hilar lymphadenopathy and pneumothorax are uncommon findings. [radiopaedia.org] Bronchogenic Carcinoma CONCLUSIONS: TBNA is a clinically useful, cost-effective technique in patients with BC and mediastinal or hilar lymphadenopathies. [ncbi.nlm.nih.gov] METHODS: Between July 2009 and February 2010, 95 patients with mediastinal/hilar lymphadenopathy and/or intrathoracic peritracheal or peribronchial masses detected with computed [ncbi.nlm.nih.gov] DD of hilar enlargement 11. DD of hilar lymphadenopathy 12. [slideshare.net] Renal Sarcoidosis The absence of bilateral hilar lymphadenopathy (BHL) was a distinctly unusual feature of sarcoidosis although uveitis and rectal granuloma were observed during the clinical [ncbi.nlm.nih.gov] Abstract Sarcoidosis commonly presents in young adults with bilateral hilar lymphadenopathy, lung parenchymal disease and/or skin lesions. [ncbi.nlm.nih.gov] periarthritis, and bilateral hilar lymphadenopathy), and Heerfordt's syndrome (uveitis and parotiditis). [renalandurologynews.com] Cutaneous Sarcoidosis It is more commonly observed in young and middle-aged individuals who present with acute onset sarcoidosis characterized by erythema nodosum, associated with bilateral hilar [archbronconeumol.org] lymphadenopathy and polyarthralgia or polyarthritis.1 However, isolated cutaneous lesions in the absence of systemic involvement may occur in the context of chronic sarcoidosis [archbronconeumol.org] Computed tomography revealed bilateral hilar and mediastinal lymphadenopathy. Ophthalmological examination showed elevated intraocular pressure. [ncbi.nlm.nih.gov] Tracheobronchial Amyloidosis Abstract We report a case of amyloidosis, restricted to the lower respiratory tract, with prominent tracheobronchial involvement and bilateral hilar lymphadenopathy, associated [ncbi.nlm.nih.gov] Valeyre, Tracheobronchial amyloidosis with hilar lymphadenopathy associated with a serum monoclonal immunoglobulin, Eur Respir J, 6 (1993), 1569‒1571. L. Ding, W. Li, K. [ashdin.com] This patient has mediastinal and hilar lymphadenopathy as well. [ucdenver.edu] Pulmonary Cavitary Tuberculosis Hilar or mediastinal lymphadenopathy ( bihilar lymphadenopathy ) - Enlargement of lymph nodes in one or both hila or within the mediastinum, with or without associated atelectasis [en.wikipedia.org] The presence of hilar and mediastinal lymphadenopathy may distinguish primary from postprimary tuberculosis, because lymphadenopathy is conspicuously absent in postprimary [emedicine.medscape.com] Although there are findings that would indicate primary TB (mid-lung infiltrates with hilar lymphadenopathy) or reactivation TB (upper lobe fibro-cavitary disease), nonspecific [journalofethics.ama-assn.org] Pulmonary Lymphoma No significant mediastinal or hilar lymphadenopathy was noted. [ijpmonline.org] lymphadenopathy also Hilar lymph nodes involved bilaterally in 50% Bronchovascular form (most common type of involvement) Coarse reticulonodular pattern contiguous with mediastinum [learningradiology.com] There was neither mediastinal nor hilar lymphadenopathy. No pleural effusion and no pleural nodules or any other lesions. [pagepress.org] Drug-induced Fever Fever, if present, is usually seen in association with erythema nodosum, polyarthralgia and hilar lymphadenopathy. [antimicrobe.org] It typically presents in persons 20-40 years of age with bilateral hilar lymphadenopathy, pulmonary infiltrates, and ocular and dermatological manifestations. [antimicrobe.org] Chronic Eosinophilic Pneumonia Six months after the contact had been made, chest radiography showed left upper lobe infiltrates without hilar lymphadenopathy, which led to the start of an antituberculous [ncbi.nlm.nih.gov] A 34 year old Japanese woman was referred to our university hospital due to pulmonary opacities and bilateral hilar lymphadenopathy on chest X-ray. [ncbi.nlm.nih.gov] A 38-year-old man was hospitalized in our university hospital because of pulmonary opacities with bilateral hilar and mediastinal lymphadenopathy seen on chest radiograph. [ncbi.nlm.nih.gov] Honeycomb Lung Sarcoidosis - Gross Photographs Bilateral hilar lymphadenopathy Biilateral hilar lymphadenopathy Parenchymal and pleural scarring Cllick on thumbnail photo to view larger [granuloma.homestead.com] lymphadenopathy and lung involvement type 4 hypersensitivity- cell mediated HLA types are predisposed infectious etiology possible non-specific non-caseating granulomata [quizlet.com] Hilar lymphadenopathy is visible in 50% and usually there is a history of malignancy. [radiologyassistant.nl] Hepatic Sarcoidosis It most commonly affects young adults and usually manifests with bilateral hilar lymphadenopathy or pulmonary infiltrates. [ncbi.nlm.nih.gov] Chest x-ray for evidence of pulmonary sarcoidosis revealed no hilar lymphadenopathy or pulmonary infiltrates. Figure 3. [acgcasereports.gi.org] Chest computed tomography (CT) showed hilar and mediastinal lymphadenopathy. [acgcasereports.gi.org] Pulmonary Tularemia We suggest that tularemia should be considered in the differential diagnosis of pneumonia with mediastinal and/or hilar lymphadenopathy. [ncbi.nlm.nih.gov] […] typhoidal hepatomegaly splenomegaly pneumonia Imaging Chest radiography indication suspected pulmonary involvement findings pulmonary infiltrates hilar lymphadenopathy pleural [step2.medbullets.com] […] conjunctivitis pharyngitis typhoidal nausea vomiting Physical exam high fever ulceroglandular tender maculopapular rash initially lesion may ulcerate with a raised border tender lymphadenopathy [step2.medbullets.com] Restrictive Lung Disease Besides sarcoidosis, several other conditions can cause bilateral hilar lymphadenopathy on a chest radiograph. [dummies.com] Clinical FeaturesFour stages are identified:s Stage 0: No obvious intrathoracic involvements Stage 1: Bilateral hilar lymphadenopathy, often accompanied by arthritis, uveitis [slideshare.net] The classic chest radiograph finding is bilateral hilar lymphadenopathy. Other possible findings include bilateral pulmonary infiltrates. [dummies.com] Berylliosis Mediastinal or hilar lymphadenopathy was shown in three cases. [ncbi.nlm.nih.gov] In later stages interstitial fibrosis, pleural irregularities, hilar lymphadenopathy and ground-glass opacities have been reported. [en.wikipedia.org] lymphadenopathy may also be present in a proportion of cases. [radiopaedia.org] Chronic Berylliosis Mediastinal or hilar lymphadenopathy was shown in three cases. [ncbi.nlm.nih.gov] lymphadenopathy may also be present in a proportion of cases. [radiopaedia.org] In later stages interstitial fibrosis, pleural irregularities, hilar lymphadenopathy and ground-glass opacities have been reported. [en.wikipedia.org] Hyponatremia It may present with bilateral hilar lymphadenopathy, skin lesions, eye and musculoskeletal system involvement. [ncbi.nlm.nih.gov] On thorax CT, bilateral hilar lymphadenopathy was seen ( Fig. 1 ). [reumatologiaclinica.org] It may present with bilateral hilar lymphadenopathy, skin lesions, the involvement of eye and symptoms on the locomotor system. [reumatologiaclinica.org] Mycoplasma Pneumonia Other radiological features were bilateral lesions in 51% of patients, pleural effusion in 23%, and hilar lymphadenopathy in 13%. [ncbi.nlm.nih.gov] Other reported plain film findings include bilateral lesions, pleural effusion (uncommon - in 25% of cases) and hilar lymphadenopathy. [radiopaedia.org] Malt Worker's Lung Upper zone mottling/consolidation; hilar lymphadenopathy (rare); honeycomb lung What would lung function tests show in EAA? [quizlet.com] It can also be a cause of bilateral hilar lymphadenopathy (remember battle 3.1?) Spirometry gives a restrictive picture and lavage will show lymphocytes. [mrcpandme.blogspot.com] May show upper-zone mottling/ consolidation, ground-glass appearance with alveolar shadowing or nodular opacities in the middle and lower zones, hilar lymphadenopathy (rare [clumsylostmedicalstudent.wordpress.com] Periodontitis They also showed that patients may develop sarcoidosis after the onset of pars planitis.[46] Pulmonary manifestations such as hilar lymphadenopathy, serum ACE and lysozyme [ncbi.nlm.nih.gov]
