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881 Possible Causes for Hirsutism, Hyperpigmentation

  • Acromegaly

    […] eyelids Increased body hair ( hypertrichosis ), excessive sweating ( hyperhidrosis ), and oily skin ( seborrhoea ) Increased number of skin tags and darkening of the skin ( hyperpigmentation[dermnetnz.org] […] growths) Sleep apnea Widened fingers or toes, with swelling, redness, and pain Other symptoms that may occur with this disease: Colon polyps Excess hair growth in females ( hirsutism[medlineplus.gov] […] vocal cords, resulting in a characteristic thick, deep voice and slowing of speech skull, frontal bossing mandible: prognathism with gaping teeth skin changes hypertrichosis hyperpigmentation[radiopaedia.org]

  • Cushing's Disease

    The disease manifests with signs of CS (truncal and facial obesity and signs of hypercatabolism) as well as skin hyperpigmentation and/or neurological complications in some[orpha.net] The clinical signs suggesting Cushing's disease, such as obesity, moon face, hirsutism, and facial plethora are already present on presentation.[ncbi.nlm.nih.gov] Hyperpigmentation of the skin may occur due to the fact that circulating ACTH has some melanocyte stimulating hormone (MSH) like activity.[symptoma.com]

  • Porphyria

    Symptoms are: blisters on areas of the skin exposed to the sun such as the face, arms, and hands followed by crusting and scarring; hyperpigmentation; increased hair growth[publichealth.va.gov] Most of the time the facial hairs are fine, so the hirsutism is barely noticeable.[scientificamerican.com] The affected areas of skin also tend to be fragile and show hyperpigmentation (excess pigment) and hypertrichosis (excess hair).[medicinenet.com]

  • Addison's Disease

    We herein report a case of Addison's disease caused by tuberculosis characterized by atypical hyperpigmentation, noted as exacerbation of the pigmentation of freckles and[ncbi.nlm.nih.gov] Furthermore, men can exhibit reduced fertility and libido, while women can exhibit hirsutism (abnormal hair growth on face, neck, thighs, and chest) and menstrual disorders[lifeextension.com] Herein this case report, we focus on the subtle findings of diffuse hyperpigmentation and intermittent but repetitive "flu-like" symptoms in two patients to correctly identify[ncbi.nlm.nih.gov]

  • Hypertrichosis

    Becker's nevus is cosmetically bothersome both due to the hyperpigmentation and due to the hypertrichosis which can accompany it, particularly in males.[ncbi.nlm.nih.gov] Workup of Hirsutism History Age of onset : Hirsutism, which is noticed from puberty, is indicative of idiopathic hirsutism.[lecturio.com] The complications are superficial scarring, hypopigmentation or hyperpigmentation and local infection.[e-ijd.org]

  • Insulin Resistance

    […] resistance typically presents in 1 of 3 ways: (1) disordered glucose metabolism including both diabetes and/or paradoxical hypoglycaemia; (2) acanthosis nigricans, a velvety hyperpigmentation[ncbi.nlm.nih.gov] Case 1 presented with premature adrenarche aged 7 years, then by age 12 years had hirsutism, acne, acanthosis nigricans, and asymptomatic diabetes.[ncbi.nlm.nih.gov] Using exome sequencing, we identified a homozygous frameshift mutation (c.1047_1048dupC; p.G337Rfs*25) in a patient presenting with short stature, facial hirsutism, alopecia[ncbi.nlm.nih.gov]

  • Testosterone

    He was referred to our polyclinic by endocrinologist because of progressive hyperpigmentation marked on his face and oral mucosa.[ncbi.nlm.nih.gov] The study describes the case of a patient, in which as a result of removing an endometrioid ovarian cyst, there was an improvement as regards hirsutism and the decrease of[ncbi.nlm.nih.gov] Menstruation began the month after the operation, and the hirsutism gradually regressed.[ncbi.nlm.nih.gov]

  • Carney Complex Type 1

    Carney complex and its subsets LAMB syndrome and NAME syndrome are autosomal dominant conditions comprising myxomas of the heart and skin, hyperpigmentation of the skin (lentiginosis[dailyrounds.org] All symptoms of Cushing syndrome including hirsutism and menstrual disturbances resolved after bilateral adrenalectomy...[readbyqxmd.com] […] this definition: Carney complex Carney complex and its subsets LAMB syndrome and NAME syndrome are autosomal dominant conditions comprising myxomas of the heart and skin, hyperpigmentation[definitions.net]

  • Generalized Lipodystrophy

    The patient had several cutaneous manifestations, including severe acanthosis nigricans, generalized hyperpigmentation, curly scalp hair, prominent subcutaneous veins, and[ncbi.nlm.nih.gov] The diagnosis is made on the basis of lack of body fat, muscular hypertrophy, acanthosis nigricans, hirsutism, hepatomegaly with fatty liver, hyperlipidemia and hyperglycemia[ncbi.nlm.nih.gov] Our patient presented with generalized loss of subcutaneous fat, prominent pectoral and thigh muscles, severe acanthosis nigricans, generalized hyperpigmentation, prominent[ijdvl.com]

  • Variegate Porphyria

    It is characterized by skin hyperpigmentation and hypertrichosis, abdominal pain, tachycardia, hypertension and neuromuscular disturbances.[uniprot.org] We present the case of two sisters showing cutaneous signs typical of PCT: blisters, photosensitivity, hyperpigmentation, hypertrichosis, cutaneous fragility, and no acute[porphyria.eu] Facial hyperpigmentation and hypertrichosis may occur.[ncbi.nlm.nih.gov]

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