HLA-A1, B8, DR3 is known to be in linkage disequilibrium with a deletion of C4A (the C4 null allele or C4QO).
[dermaamin.com]
Immunogenetic studies reveal an increase in HLA antigens DR3 or DR4, and curiously, nearly 50 percent of patients have the simultaneous presence of both. 21 The extended haplotype
[dermaamin.com]
In the sequel study, Garchon and coworkers reevaluated the contribution of the extended 8.1 HLA haplotype, including Class I HLA-A1 and B8 loci and Class II HLA-DR3 allele
[hindawi.com]
The histocompatibility complex profile includes HLA-A1, -A3, -B7, -B8, -DRw3, and -DQw2 (though these have not been shown to be associated with the strictly ocular form of
[emedicine.medscape.com]
In addition, HLA-B*08 and -DRB1*03 alleles were shown to be in linkage disequilibrium, thus, forming a haplotype from which the A1 locus appeared to be unexpectedly excluded
[hindawi.com]
It is associated with an increased expression of HLA-A1, HLA-B8, and HLA-DR3 antibodies.
[fpnotebook.com]
The condition seems to have a genetic predisposition with increased expression of the HLA-A1, HLA-B8, HLA-DR3, and HLA-DQ2 haplotypes and IgA deposits in the papillary dermis
[symptoma.com]
The type II syndrome differs from type I in that it is associated with HLA-A1 and B8 haplotypes, onset is usually in adulthood, and candidiasis is not present.
[medvik.cz]
The type II syndrome differs from type I in that it is associated with HLA-A1 and B8 haplotypes, onset is usually in adulthood, and candidiasis is not present Note générale
[idref.fr]
It is associated with an increased expression of HLA-A1, HLA-B8, and HLA-DR3 antibodies.
[fpnotebook.com]
Patients with dermatitis herpetiformis have an increased expression of the HLA-A1, HLA-B8, HLA-DR3, and HLA-DQ2 haplotypes.
[emedicine.medscape.com]
Both dermatitis herpetiformis and celiac disease (CD) are associated with an increased expression of HLA-A1, HLA-B8, HLA-DR3, and HLA-DQ2 haplotypes.
[emedicine.medscape.com]
The type II syndrome differs from type I in that it is associated with HLA-A1 and B8 haplotypes, onset is usually in adulthood, and candidiasis is not present Note générale
[idref.fr]
The type II syndrome differs from type I in that it is associated with HLA-A1 and B8 haplotypes, onset is usually in adulthood, and candidiasis is not present.
[fpnotebook.com]
The type II syndrome differs from type I in that it is associated with HLA-A1 and B8 haplotypes, onset is usually in adulthood, and candidiasis is not present.
[fpnotebook.com]
The type II syndrome differs from type I in that it is associated with HLA-A1 and B8 haplotypes, onset is usually in adulthood, and candidiasis is not present Note générale
[idref.fr]
DRB1 and DQ B1 have been associated with acute sarcoidosis and a good prognosis, and HLA A1, B7, B8, B13, DR3, DR5, DR14, DR15 and DRl7 with familial cases 1, 6.
[erj.ersjournals.com]
HLA analyses of affected families showed that inheritance of the risk for sarcoidosis can be polygenic, most commonly including the class I HLA-A1 and -B8 and class II HLADR3
[peertechz.com]
[…] review of literature, we have found that human leukocyte antigen (HLA) genotypes DR 11, 12, 13, 14, 15 and 17 have been reported to confer susceptibility to the disease, HLA
[erj.ersjournals.com]
The ANA- granddaughter (daughter of the proband) was noted to have severe isolated pulmonary hypertension within the first 6 months of life, and had the other maternal HLA-A1
[ncbi.nlm.nih.gov]
Five of 9 cases carried the haplotype HLA-A1, B8, DR3.
[ncbi.nlm.nih.gov]
HLA-A1 is twice as frequent in lymphocytic colitis patients than in normal control patients or those with collagenous colitis.
[incytepathology.wordpress.com]
Increased HLA A1 and diminished HLA A3 in lymphocytic colitis compared to controls and patients with collagenous colitis. Dig Dis Sci. 1992 Apr. 37(4):496-9. [Medline].
[emedicine.medscape.com]
In the non-alcoholic sub-group of 36 patients, the incidence of HLA-A1 was significantly higher than in controls ( P c =0.0021); whilst HLA-B8 was present in 38.8% of patients
[link.springer.com]
When these data are amalgamated with data from Lyon (France), the antigen HLA-A1 is significantly associated with non-alcoholic chronic pancreatitis.
[link.springer.com]
In the subgroup of 52 patients with alcohol-related chronic pancreatitis HLA-B21 was significantly increased in frequency compared with 344 local controls ( P c =0.0128).
[link.springer.com]
Later studies have verified that PSC associations exist also for the other alleles of the AH8.1 (the HLA-A1 allele[51], the HLA-C7 allele[52], the major histocompatibility
[psc-literature.org]
The underlying cause is unknown but there is thought to be an autoimmune component with a higher prevalence of certain HLA alleles (A1, B8, DR3).
[oxfordmedicaleducation.com]
[…] alleles A1, B8, and DR3 in PSC. [11, 12] An autoimmune mechanism is suggested, because approximately 75-90% of patients with PSC have inflammatory bowel disease (IBD).
[emedicine.com]
Regarding HLA haplotypes associated with autoimmune hepatitis,30 11 of 25 patients (44%) had HLA A1 (only 1 of these had an elevated autoimmune score), 6 of 25 (24%) had HLA
[hepatitiscentral.com]
Regarding HLA haplotypes associated with autoimmune hepatitis, 30 11 of 25 patients (44%) had HLA A1 (only 1 of these had an elevated autoimmune score), 6 of 25 (24%) had
[hepatitiscentral.com]
Only 1 had the extended HLA A1-B8-DR3 haplotype. Laboratory parameters (table 1) were not significantly different between the risk subgroups.
[hepatitiscentral.com]
Three underwent renal biopsy which displayed characteristic features of focal glomerulosclerosis and all shared the HLA alleles HLA-A1, B8, DR3, DR7.
[ncbi.nlm.nih.gov]
[…] alleles HLA-A1, B8, DR3, DR7 may increase the predisposition to familial glomerulosclerosis but additional factors are required for disease development and progression.
[ncbi.nlm.nih.gov]
The index case received two cadaveric renal transplants from HLA-A1, B8, DR3 donors and developed chronic rejection with no histological evidence of recurrent glomerulonephritis
[ncbi.nlm.nih.gov]
It is associated with an increased expression of hla-a1, hla-b8, and hla-dr3 antibodies.
[icd9data.com]
The relative risk to develop hepatosplenomegaly in persons infected with S. mansoni have been reported in correlation with HLA-A1 and B5[ 15 ].
[wjgnet.com]
[…] phosphorus abnormality in people suffering from calcific tendonitis, although – in those suffering with calcific tendonitis – there does appear to be a higher incidence of the HLA-A1
[perfectbalanceclinic.com]
However, an increase in HLA-A1 has been observed in patients with this disorder.
[clinicaladvisor.com]
Second, strong association between HLA-A1 antigen and CPH (Fisher exact = 0.000022).
[ncbi.nlm.nih.gov]
Type 1 AIH in Caucasians is associated with the HLA-DR3 serotype, which is found in linkage disequilibrium with HLA-B8 and HLA-A1 and in HLA-DR3 -negative patients with HLA-DR4
[doi.org]
Biological context of IgA Deficiency Nine of 11 patients with C4A deletion had an HLA haplotype consistent with the MHC supratype HLA-A1, Cw7, B8, C4AQ0, C4B1, BfS, DR3 previously
[wikigenes.org]
As clearly suggested by investigation of families, the findings could be attributed to high prevalence of the extended major histocompatibility complex (MHC) haplotype [HLA-A1
[wikigenes.org]
Fine-scale mapping at IGAD1 and genome-wide genetic linkage analysis implicate HLA-DQ/DR as a major susceptibility locus in selective IgA deficiency and common variable immunodeficiency
[wikigenes.org]
Later studies have verified that PSC associations exist also for the other alleles of the AH8.1 (the HLA-A1 allele[51], the HLA-C7 allele[52], the major histocompatibility
[psc-literature.org]
Genetic studies have demonstrated the expression of the haplotypes HLA A1-B8-DR3, DR-6, and DR-2 in some cases of PSC.
[scielo.br]
Multiple candidate genes have been associated with PSC, including HLA-DRB1*1501-DQB1*602, HLA-DRB1*1301-DQB1*0603 and HLA-A1-B8-DRB1*0301-DQB1*0201 [ 9 ].
[oapublishinglondon.com]
The type II syndrome differs from type I in that it is associated with HLA-A1 and B8 haplotypes, onset is usually in adulthood, and candidiasis is not present.
[hon.ch]
[…] fact, in some cases, it may present before other features of IBD. 5-10% of UC will also have PSC 1% of Crohn’s patients will have PSC Genetic component – associated with HLA
[almostadoctor.co.uk]
HLA analyses of affected families suggest a polygenic mode of inheritance of risk for sarcoidosis; the most commonly found alleles include class I HLA-A1 and B8 and class
[emedicine.medscape.com]
[…] frequencies of HLA-A1 (44% v 35%) and HLA-B8 (34% v 27%) antigens, 18 and of the haplotype HLA-A1, B8, DR3 (25% v 4%–6%), compared with the general population.
[web.archive.org]
Increased susceptibility to infection might be inherited as there is some indication that HLA-A1 or factors surrounding A1 on extended haplotypes are involved in virus infection
[en.wikipedia.org]
Despite other minor non-significant variations in immunoglobulin levels at this review, no subject had clinical problems related to this. 13, 17 HLA testing showed increased
[web.archive.org]
reveal that HLA-A1, HLA-B8, and HLA-DR3 are more common in persons with SLE than in the general population.
[emedicine.medscape.com]
FAM167A-BLK, BANK1 and KIAA1542); however, those loci had a lower significance level and a lower contribution to individual risk for SLE. [33] Studies of human leukocyte antigens (HLAs
[emedicine.medscape.com]
The parents had identical HLA alleles A1, A2, and Bw21. The mechanism of the triploidy was determined by chromosome marker analysis to be digyny.
[ncbi.nlm.nih.gov]
HLA typing revealed that all affected subjects bore the haplotype A1 B12 DR3.
[ncbi.nlm.nih.gov]
[…] that all affected patients carried the haplotype A1 B12 DR3.
[cags.org.ae]
The employment of electron microscopy on biopsies of synovium and cartilage of single patient revealed calcium pyrophosphate dehydrogenase crystals, meanwhile HLA typing demonstrated
[cags.org.ae]
The type II syndrome differs from type I in that it is associated with HLA-A1 and B8 haplotypes, onset is usually in adulthood, and candidiasis is not present.
[medvik.cz]
