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139 Possible Causes for HLA-B12

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  • Anisakis

    Class I HLA expressed by the patient was type HLA-B12. Other secondary causes of nephrotic syndrome were carefully ruled out.[ncbi.nlm.nih.gov]

  • Biliary Atresia

    We found, especially in those without associated malformations, a significantly higher frequency of HLA -B12, of haplotypes A9-B5 and A28-B35, and of their disequilibrium[journals.lww.com] To test the hypothesis that susceptibility to this disease would be influenced by host genetic factors, we studied the human leukocyte antigen ( HLA ) system in 55 patients[journals.lww.com]

  • Stevens-Johnson Syndrome

    HLA-A29, HLA-B12, and HLA-DR7 are frequently associated with sulfonamide-induced Stevens-Johnson syndrome, while HLA-A2 and HLA-B12 are often encountered in Stevens-Johnson[emedicine.medscape.com] […] at greatest risk of inciting SJS A*0206 SJS with ocular disease A2 NSAIDs A29 Sulfonamides B12 Sulfonamides, NSAIDs B15:02 Aromatic anticonvulsants B58:01 Allopurinol DR7[eyewiki.org] Carriage of the following human leukocyte antigens has been associated with increased risk: HLA-B*1502 HLA-B*5801 HLA-B*44 HLA-A29 HLA-B12 HLA-DR7 HLA-A2 HLA-B*5801 HLA-A*[emedicine.medscape.com]

  • Stomatitis

    Nutritional deficiencies (iron, folate, ferritin, vitamin B 6 , vitamin B 12 ) Tobacco cessation Medications, for example, methotrexate , NSAIDS, phenobarbital Immunologic: HLA-B12[unboundmedicine.com]

  • Pauci-Immune Glomerulonephritis

    Nevertheless, there are anecdotal reports of association of MCD and atopy with HLA-B12. [13] 1. Bonaci-Nicolic B, Nicolic MM, Andrejevic S, et al.[sjkdt.org]

  • Recurrent Oral Ulceration

    These results suggest that HLA-B12, B5, DR7 and DR2 might in some way be associated with tissue localization of disease.[ncbi.nlm.nih.gov] […] least 40% of people with aphthous stomatitis have a positive family history, suggesting that some people are genetically predisposed to suffering with oral ulceration. [6] HLA-B12[en.wikipedia.org] This is shown by a positive family history in about one-third of patients with RAS; an increased frequency of human leukocyte antigen (HLA) types A2, A11, B12, and DR2; and[emedicine.medscape.com]

  • Birdshot Chorioretinopathy

    The HLA-B12 (B44) antigen was also significantly associated with the disease, but this antigen is known to be in linkage disequilibrium with the antigen HLA-A29.[ncbi.nlm.nih.gov] Positivity for the HLA-B12 antigen may also be linked to Birdshot Chorioretinopathy, although this causation has not been confirmed.[raregenomics.org] […] patients [ 2 ] ) and, to a lesser extent, HLA-B12 positivity. [ 3 ] It is the strongest HLA association with any known disease. [ 3 ] There are progressive abnormalities which[patient.info]

  • Toxic Epidermal Necrolysis

    Genetic susceptibility may also be involved, as studies have found that the HLA-B12 gene is associated with a higher risk of the disease. 4 Morbidity and mortality.[aao.org]

  • Thromboangiitis Obliterans

    De Moerloose et al. (1979) found a deficiency of HLA-B12 in patients with Buerger disease (2.2% vs 28% in controls).[omim.org] HLA-B12 antigen may be associated with disease resistance.[unboundmedicine.com] De Moerloose et al . [ 21 ] found a marked decrease in frequency of the HLA-B12 antigen in patients with Buerger's disease (2.2% vs . 28% in controls).[ncbi.nlm.nih.gov]

  • Myasthenia Gravis

    Myasthenia gravis Eye deviation and a drooping eyelid in a person with myasthenia gravis trying to open her eyes Specialty Neurology Symptoms Varying degrees muscle weakness , double vision , drooping eyelids , trouble talking, trouble walking Zhang, Zhenchang; Guo, Jia; Su, Gang; Li, Jiong; Wu, Hua; Xie, Xiaodong[…][en.wikipedia.org]

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