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196 Possible Causes for HLA-B27, Joint Swelling, Knee Pain

  • Psoriatic Arthritis

    While a number of genes are linked to PsA, the highest predictive value is noted with HLA-B27.[spondylitis.org] The plaques were associated with fever, and intermittent knee pain and swelling.[ncbi.nlm.nih.gov] Doctors will do a physical examination to check for joint swelling and tenderness around the affected area.[sharecare.com]

  • Reiter's Syndrome

    People with reactive arthritis may experience swelling and tenderness of one ankle or knee; pain in the heel of the foot; inflammation and pain of the Achilles tendon (located[healthcentral.com] HLA B27 was present in 11 (61.1%) patients.[ncbi.nlm.nih.gov] Reactive arthritis is pain or swelling in a joint that is caused by an infection in your body. You may also have red, swollen eyes and a swollen urinary tract.[niams.nih.gov]

  • Ankylosing Spondylitis

    In literature, although the evidence for association between AS and periodontitis as well as AS and HLA-B27 are there but the association of aggressive periodontitis in HLA-B27[ncbi.nlm.nih.gov] When the condition presents before the age of 18, it is relatively likely to cause pain and swelling of large limb joints, particularly the knee.[jaipurarthritiscentre.com] The joint problems involve large joints, such as the hips and sacroiliac joints. Swelling of entire toes or fingers, resulting in sausage digits, also occurs.[northshore.org]

  • Oligoarthritis

    And I walked up the stairs and the pain was gone. You know how painful it is to have that thing in your knee.[paddisonprogram.com] HLA B27 antigen was studied and family history was reexamined in 2006. Five patients had sacroiliitis.[ncbi.nlm.nih.gov] Oligoarticular JIA affects 4 or fewer joints during the first 6 months of the disease. Symptoms tend to be limited to joint swelling and pain.[myhealth.alberta.ca]

  • Juvenile Rheumatoid Arthritis

    There is significant correlation between ANA seropositivity and HLA-B27, early erosion, response to treatment, uveitis and subcutaneous nodule.[ncbi.nlm.nih.gov] pain.[web.archive.org] He suffered from fever and generalized rash followed by multiple joints swelling for four months before admission.[ncbi.nlm.nih.gov]

  • Arthritis of Inflammatory Bowel Disease

    The human leukocyte antigen (HLA)-B27 is a well recognised best-known predisposing factor.[ncbi.nlm.nih.gov] Knee pain and swelling due to Crohn Disease: A case report. Journal of Bone and Joint Surgery, 87(8). 7. Marks, R., & Cantin, D. (1997).[painmanagement.org.au] Signs and Symptoms Diagnosis Treatment Symptoms of arthritis (joint pain, swelling and stiffness) usually occur at the same time a person is experiencing symptoms of IBD.[ucsfhealth.org]

  • Polyarticular Juvenile Idiopathic Arthritis

    B27-positivity in males with onset of arthritis after 6 years of age.[orpha.net] CLINICAL CASE: This is the case of RF-negative polyarticular juvenile idiopathic arthritis that was reported with six-week history of neck pain, torticollis and left knee[ncbi.nlm.nih.gov] She was diagnosed with RF-positive polyarticular JIA based on positive RF and multiple joint swelling and tenderness 3 years ago.[ncbi.nlm.nih.gov]

  • Arthritis

    It is thought that HLA-B27 may affect the elimination of the infecting bacteria or an individual’s immune response. [1] HLA-B27 has been shown to be a predisposing factor[about-reactive-arthritis.com] The secondary outcomes were knee pain score (range, 1-6), performance measures of physical function, x-ray score, aerobic capacity, and knee muscle strength. Results.[doi.org] Glucocorticoids can rapidly alleviate joint swelling and pain.[ncbi.nlm.nih.gov]

  • Polyarthritis

    Anti-citrullinated protein antibody (ACPA), rheumatoid factor, human leucocyte antigen (HLA) B27 and imaging are routinely employed for the early diagnosis of RA and spondyloarthritis[ncbi.nlm.nih.gov] He also complained of shoulders, hips and knees pain with morning stiffness lasting 45 minutes.[ard.bmj.com] Associated conditions [ edit ] It may be associated with bilateral edema in lower limbs, pain and joint swelling.[en.wikipedia.org]

  • Arthropathy

    Our GP said that I have a greater risk for joint disease because I am HLA-B27 . what is he talking about?[medical-dictionary.thefreedictionary.com] Shoulders – syrinx, spinal tumor Hips – tertiary syphilis, diabetes Knees – tertiary syphilis (more bone production), diabetes (less bone production) Feet – diabetes Other[learningradiology.com] Charcot arthropathy neuropathic arthropathy . chondrocalcific arthropathy progressive polyarthritis with joint swelling and bony enlargement, most commonly in the small joints[web.archive.org]

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