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383 Possible Causes for HLA-B27, Weight Loss

  • Arthritis of Inflammatory Bowel Disease

    Other symptoms may include Anemia Severe tiredness Weight loss Loss of appetite Bleeding from the rectum Sores on the skin Joint pain Growth failure in children About half[medlineplus.gov] The human leukocyte antigen (HLA)-B27 is a well recognised best-known predisposing factor.[ncbi.nlm.nih.gov] […] unexpected weight loss.[nyulangone.org]

  • Enthesitis-Related Arthritis

    When the disease is active, up to 10% of patients will develop systemic manifestations such as fever, weight loss, fatigue, muscle weakness, muscle atrophy, and lymphadenopathy[symptoma.com] […] method permitted identification of common HLA-B27 subtypes (HLA-B*27:01 to HLA-B*27:09).[ncbi.nlm.nih.gov] loss.[enthesis.info]

  • Crohn's Disease

    Symptoms include fever, diarrhea, stomach cramps, vomiting, and weight loss. Regional enteritis increases the risk of colorectal cancer and small intestine cancer.[icd9data.com] However, they have only a transient benefit in HLA-B27 transgenic rats[ 24 ].[doi.org] Symptoms include abdominal pain and diarrhea, sometimes bloody, and weight loss.[webmd.com]

  • Juvenile Rheumatoid Arthritis

    Low-grade fever, weight loss, and anemia may occur, as well as growth problems in severe cases.[arthritis.about.com] There is significant correlation between ANA seropositivity and HLA-B27, early erosion, response to treatment, uveitis and subcutaneous nodule.[ncbi.nlm.nih.gov] Because of other symptoms, the child may simply not want to eat, which will naturally result in weight loss.[chronicbodypain.net]

  • Whipple Disease

    Abstract A 72-year-old man presented with a 6-month history of dysphagia, fatigue, 60-lb weight loss, and central nervous system (CNS) deficits.[ncbi.nlm.nih.gov] About 30% of patients have HLA-B27. Drugs Mentioned In This Article PLAQUENIL No US brand name ROCEPHIN PERIOSTAT, VIBRAMYCIN[merckmanuals.com] HLA-B27 antigen; HLA-DRB1*13 and DQB1*06 alleles. [ 9 ] Sewage plant workers, farmers and agricultural workers.[patient.info]

  • Juvenile Seronegative Polyarthritis

    May be associated with weight loss or family history. Malignancy: Night pain, weight loss, easy bruising can all be features.[patient.info] The HLA B27-positive patients contracted amyloidosis on average 5.9 (median 6.7) years earlier than the HLA B27-negative patients ( p 0.038).[link.springer.com] Systemic symptoms should also be sought - eg, fever and weight loss [ 5 ].[patient.info]

  • Tubulointerstitial Nephritis-Uveitis Syndrome

    Abstract Tubulointerstitial nephritis and uveitis syndrome presents with either renal or ocular manifestations, and associated weight loss.[pediatrics.aappublications.org] B27 typing : negative HLA B27 typing : negative 6 First Diagnosis  Idiopathic anterior uveitis  Treatment: intensive steroid drops and ointment at bedtime (with progressive[slideplayer.com] A 61-year-old woman was admitted to this hospital because of a 2-month history of abdominal pain and weight loss and an elevated serum creatinine level.[nejm.org]

  • Spondylitis

    Symptoms suggestive of inflammatory bowel disease include abdominal pain, blood in the stool and weight loss. Both genetic and environmental factors cause JAS.[chop.edu] Many HLA-B27 positive don’t get AS, and some people without it do. Prevalence 2-8% (30% in eskimos!)[oxfordmedicaleducation.com] AS can cause other symptoms such as appetite loss, weight loss, fatigue, fever, anemia, eye inflammation, and digestive illness.[urmc.rochester.edu]

  • Influenza

    […] but exhibited less than 10% weight loss and was excluded from kinetics in ( f ).[doi.org] Structural homologies between two HLA B27-restricted peptides suggest residues important for interaction with HLA B27. Int Immunol 2 : 311 –6. Hughes AL, Nei M. 1988 .[dx.doi.org] Infection with a high virus dose (2,000 PFU) led to markedly increased mortality in IL-1R1 / mice (Fig. 1B ), which was not associated with increased weight loss (Fig. 1C[doi.org]

  • Juvenile Ankylosing Spondylitis

    Nonspecific complaints which may also be reported by the young patients include a kyphotic appearance due to progressed disease that has affected the spine, weight loss, decreased[symptoma.com] Nine of the 10 patients exhibited the genetic marker HLA B27, but only one patient was homozygous for HLA B27.[ncbi.nlm.nih.gov] Symptoms suggestive of inflammatory bowel disease include abdominal pain, blood in the stool and weight loss. Both genetic and environmental factors cause JAS.[chop.edu]

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