Question 1 of 10

    120 Possible Causes for HLA DQ2 in USA

    • Celiac Disease
      HLA-DQ2

      What is the meaning of HLA DQ2/DQ8?[massgeneral.org] Genetic susceptibility defines people who possess the gene pair encoding the major histocompatibility complex class II HLA DQ2 or DQ8.[clevelandclinicmeded.com] Finally, CD is likely to be rare in Japan, Indonesia, Korea, the Philippines and many smaller Pacific islands because of low wheat consumption and a low frequency of HLA-DQ2[journals.lww.com]

    • Childhood Celiac Disease
      HLA-DQ2

      HLA-DQ2 and HLA-DQ8 Genes 95% of people with celiac disease have either or both of the HLA-DQ2 or HLA-DQ8 genes.[beyondceliac.org] HLA-DQ2-restricted T-cell recognition of gluten-derived peptides in celiac disease.[gi.org] Methods We performed a multicenter, randomized, double-blind, placebo-controlled dietary-intervention study involving 944 children who were positive for HLA-DQ2 or HLA-DQ8[drschaer-institute.com]

    • Dyspepsia

      Moreover, most patients in this study with clinically-confirmed enteropathy (84.1%) had the genetic locus for celiac disease susceptibility (HLA DQ2 or -DQ8), indicating the[greenmedinfo.com] […] clinically verified enteropathy they performed typical blood tests for celiac disease (e.g. anti-tissue transglutiminase IgA antibodies), as well as genetic testing for the HLA-DQ2[greenmedinfo.com] […] stool frequency and gastrointestinal symptom score returned to normal values in 60% of diarrhea predominant IBS patients who were positive and in 12% who were negative for HLA-DQ2[greenmedinfo.com]

    • Myasthenia Gravis

      [resources.lupus.org] In white persons, for instance, the condition is linked to human leukocyte antigen (HLA)–DR3, HLA-DQ2, and HLA - B8 , [10] whereas the linkage is to[symptoma.com]

    • Celiac Disease with Diffuse Intestinal Ulceration

      HLA DQ typing Genetic testing for HLA DQ2/8 is valuable, but only as an exclusionary test.[emedmd.com] Past genetic testing revealed that this patient carries the HLA-DQ2 allele.[medbullets.com] DQ2 or DQ8 expression, dermatitis herpetiformis, hyposplenism Monomorphic variant NOT associated with celiac disease, may represent a distinct entity EATL in situ: refractory[pathologyoutlines.com]

    • Dermatitis Herpetiformis

      It is most common in patients of northern European ancestry, and is associated with the HLA-DQ2 haplotype along with celiac disease and gluten sensitivity.[kinnikinnick.com] Other tests HLA haplotype, a set of DNA variations, testing may reveal HLA-DQ2 or HLA-DQ8.[dermnetnz.org]

    • Alcoholic Cerebellar Degeneration

      The HLA DQ2 has also been seen in a number of other autoimmune diseases including primary autoimmune cerebellar ataxia.[journals.plos.org] Not surprisingly, this may trigger a breakdown in immune tolerance and autoimmune responses in patients harbouring genetic susceptibility (HLA DQ2/DQ8).[cerebellumandataxias.biomedcentral.com] Up to 90% of patients with celiac disease are HLA DQ2, the remaining have DQ8 or DQ1.[neuroweb.us]

    • Chronic Diarrhea with Villous Atrophy

      In this case, there was a high prevalence of patients with two copies of HLA-DQ2 in both groups, but no relationship between the severity of villous atrophy and HLA-DQ2 homozygosity[em-consulte.com] […] olmesartan-associated sprue-like enteropathy is uncertain, the long latency before onset of symptoms, findings of lymphocytic or collagenous colitis, and high association with HLA-DQ2[medpagetoday.com] Genetic susceptibility defines people who possess the gene pair encoding the major histocompatibility complex class II HLA DQ2 or DQ8.[clevelandclinicmeded.com]

    • Collagenous Sprue

      […] a) Refer the patient for a dietary review b) Request a clonal analysis of the intraepithelial lymphocytes c) Refer for HLA DQ2/DQ8 testing d) Refer the patient for capsule[ueg.eu] None of the patients had ever shown celiac-specific antibodies , and all were negative for HLA-DQ2 and HLA -DQ8 phenotype.[celiac.com]

    • Celiac Disease, Epilepsy and Cerebral Calcification Syndrome

      Moreover, CEC, as well as CD, is associated with HLA-DQ2 and HLA-DQ8 phenotype and genotype.[ncbi.nlm.nih.gov] Almost all people (95%) with coeliac disease have either the variant HLA-DQ2 (major) allele or the HLA-DQ8 (minor) allele.[omicsonline.org] It is associated with the HLA-DQ2 and HLA-DQ8 genes.[radiopaedia.org]

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