131 Possible Causes for HLA-DQ2

Did you mean:   hla-dr2

  • Celiac Disease

    The final study group included 553 children who were positive for HLA-DQ2, HLA-DQ8, or both ( Table 1 ).[nejm.org] What is the meaning of HLA DQ2/DQ8?[massgeneral.org] Both CD-causing factors—gluten consumption (particularly in the northern part of the country) and HLA-predisposing genotypes DQ2 and DQ8 (even though with a lower prevalence[journals.lww.com]

  • Childhood Celiac Disease

    Kaplan–Meier Estimates of CDA in HLA-DR3–DQ2 Homozygotes, According to Country.[nejm.org] Children with typical symptoms of CD, who have a tissue transglutaminase antibody level 10 times the upper limit of normal together with a positive endomysium antibody and are HLA-DQ2[journals.lww.com] Ninety percent of affected individuals carry the HLADQ2 haplotype, 5% the DQ8 haplotype, and the remaining 5% carry at least one of the two DQ2 alleles [ 1 , 2 ].[intechopen.com]

  • Acute Lymphoblastic Leukemia
  • Dyspepsia

    Moreover, most patients in this study with clinically-confirmed enteropathy (84.1%) had the genetic locus for celiac disease susceptibility (HLA DQ2 or -DQ8), indicating the[greenmedinfo.com] […] clinically verified enteropathy they performed typical blood tests for celiac disease (e.g. anti-tissue transglutiminase IgA antibodies), as well as genetic testing for the HLA-DQ2[greenmedinfo.com] […] stool frequency and gastrointestinal symptom score returned to normal values in 60% of diarrhea predominant IBS patients who were positive and in 12% who were negative for HLA-DQ2[greenmedinfo.com]

  • Abdominal Mass

    Furthermore, HLA typing was performed: a DQ2 haplotype was present, thus strengthening the diagnosis of CD.[omicsonline.org] DQ2 haplotype [ 6 ].[omicsonline.org] Introduction Celiac disease (CD) is a very frequent immune-mediated disorder triggered by gluten peptides from wheat and related cereals in genetic susceptible individuals (HLA-DQ2[omicsonline.org]

  • Autoimmune Polyendocrinopathy

    Genetic Aspects Autoimmune Addison's is closely associated with the_ HLA-DR3_ haplotype; the highest risk genotype is HLA-DR3/4-DQ2/8, found in 30% of patients.[diapedia.org] The HLA system plays a major permissive role in determining susceptibility to organ-specific autoimmunity, and HLA alleles play an important role in determining the phenotypic[diapedia.org] HLA DRB1 15-DQB1 0602 appears protective against diabetes, as in the general population.[diapedia.org]

  • Amyotrophic Lateral Sclerosis

    A vast majority of people with celiac disease have either the HLA-DQ2 or the HLA-DQ8 variant.[brainblogger.com] Deaminated gliadin produced by transglutaminase as a higher affinity for these specific variants of HLA molecules.[brainblogger.com] They found that 86.4% of patients who were seropositive for transglutaminase 6 autoantibodies also carried celiac disease susceptibility HLA variants.[brainblogger.com]

  • Autoimmune Polyglandular Syndrome Type I

    Genetic Aspects Autoimmune Addison's is closely associated with the_ HLA-DR3_ haplotype; the highest risk genotype is HLA-DR3/4-DQ2/8, found in 30% of patients.[diapedia.org] The HLA system plays a major permissive role in determining susceptibility to organ-specific autoimmunity, and HLA alleles play an important role in determining the phenotypic[diapedia.org] HLA DRB1 15-DQB1 0602 appears protective against diabetes, as in the general population.[diapedia.org]

  • Brazilian Pemphigus Foliaceus

    However, both previous studies of Euro-Brazilian and admixed populations 2 , 3 revealed a negative association of EPF with antigen HLA-DQ2 which, in turn, is associated to[nature.com] Positive and negative associations with several HLA-DR and HLA-DQ antigens and HLA-DRB1 and HLA-DQB1 alleles have been reported in white, admixed and Amerindian Brazilian[nature.com] Genetic Diversity of HLA.[nature.com]

  • Budd-Chiari Syndrome

    Indeed, 95 % of patients are either DQ2 (HLA DQA1 * 05-DQB1 * 02) or DQ8 (HLA DQA1 * 03 -DQB1 * 03), compared with 35 % in the general population [ 16 Book L., Zone J.J.,[em-consulte.com] DQ2 homozygous patients have higher risk of developing the disease than heterozygous patients.[em-consulte.com] No specific HLA class I features were noted (Table 2).[em-consulte.com]

Further symptoms