Homocysteine Increased: Causes & Reasons

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Possible Causes for Homocysteine Increased

Homocystinuria

From Wikidata Jump to navigation Jump to search amino acid metabolic disorder that involves an accumulation of homocysteine in the serum and an increased excretion of homocysteine [wikidata.org]

homocysteine, methylmalonic acid Renal insufficiency • Increased homocysteine Pregnancy Nutritional folic acid deficiency Drug related Isonicotinic acid hydrazide therapy [academic.oup.com]

Increased homocysteine results in various vascular and neurological complications. [ncbi.nlm.nih.gov]

Inadequate Dietary Intake of Folic Acid

homocysteine levels Thrombocytopenia [expand title=”References for Folic Acid Deficiency Mnemonic:”] – http://www.webmd.com/vitamins-supplements/ingredientmono-1017-folic [medical-institution.com]

Homocysteine increases as folate decreases in plasm of healthy men during short term dietary folate and methyl group restriction. J Nutr 1994;124:1072-80. [nrv.gov.au]

Although increased homocysteine concentrations in the blood have been consistently associated with increased risk of CVD, it is unclear whether lowering circulating homocysteine [lpi.oregonstate.edu]

Folic Acid Deficiency

Increased plasma homocysteine is a functional marker of both folate and vitamin B12 deficiency. Increased homocysteine levels are found in depressive patients. [ncbi.nlm.nih.gov]

There are also many data about a defect in homocysteine metabolism and increased levels of homocysteine in schizophrenic subjects but the correlation of hyperhomocysteinemia [scopemed.org]

Methylmalonic Acidemia with Homocystinuria Type cblJ

When the body cannot process vitamin B12 as it should, blood levels of homocysteine increase, and blood levels of methionine decrease. [cystadane.com]

In patients suffering from inherited conditions that interfere with the conversion of homocysteine to methionine, blood and tissue levels of homocysteine are increased while [symptoma.com]

[…] as increased blood homocysteine (339.2μmol/L, normal: <10). [elsevier.es]

Anemia due to Vitamin B6 Deficiency

Increased levels of homocysteine Increase in levels of amino acid homocysteine can increase the risk of heart attacks. [ayurtimes.com]

If homocysteine cannot be converted into cysteine, homocysteine levels in the blood will increase. [nuts.com]

This means that elevated levels of homocysteine in the blood increase the risk of these diseases. [brainblogger.com]

Methylmalonic Acidemia with Homocystinuria Type cblF

In patients suffering from inherited conditions that interfere with the conversion of homocysteine to methionine, blood and tissue levels of homocysteine are increased while [symptoma.com]

homocysteine, methylmalonic acid Renal insufficiency • Increased homocysteine Pregnancy Nutritional folic acid deficiency Drug related Isonicotinic acid hydrazide therapy [ncbi.nlm.nih.gov]

Diagnosis[edit] The term homocystinuria describes an increased excretion of the thiol amino acid homocysteine in urine (and incidentally, also an increased concentration in [en.wikipedia.org]

Methylmalonic Acidemia with Homocystinuria

In patients suffering from inherited conditions that interfere with the conversion of homocysteine to methionine, blood and tissue levels of homocysteine are increased while [symptoma.com]

The pathogenesis of thrombotic microangiopathy is related to the increase of plasma methylmalonic acid and homocysteine levels. [revistanefrologia.com]

Diagnostic methods Measurement of organic acids and amino acids, in particular evidence of increased total plasma homocysteine (tHcy), is suggestive of the disease. [orpha.net]

Transcobalamin 2 Deficiency

Small variations in TC-II affinity were recently linked to a high homocysteine level and increased frequency of neural tube defects. [ncbi.nlm.nih.gov]

Deficiency of vitamin B 12 or folic acid can lead to increased homocysteine levels. Information from Stabler SP. [aafp.org]

In this reaction, a deficiency of vitamin B 12 or folic acid may lead to increased homocysteine levels. [sites.google.com]

Vitamin B12 Deficiency

Each 5-μmol/L increase above 10 μmol/L of serum homocysteine is associated with a 20% increased risk of circulatory health problems. [ncbi.nlm.nih.gov]

Even when B12 values were ≥1500 pg/ml (n = 36), increased MMA and homocysteine values occurred in 31 and 23 % of subjects, respectively. [ncbi.nlm.nih.gov]

however, several observational studies suggest increased homocysteine levels increase the incidence of Alzheimer's disease and dementia, and low levels of vitamin B12 has [healthaliciousness.com]

Popliteal Artery Injury

[…] l of homocystein levels the relative risk for coronary heart disease increases with 40%. [tmj.ro]

These cases are more frequent in adults and produce only mild increases in homocysteine levels. [tmj.ro]

Also, increased plasma homocysteine levels may occur if there is not an adequate supply of vitamin B12, folate, or in chronic renal failure cases. [tmj.ro]

Hyperhomocysteinemia

Abstract: Elevated plasma levels of homocysteine are associated with an increased generation of reactive oxygen species in aortas of hyperhomocysteinemic animals and in endothelial [eurekaselect.com]

"Evidence of Increased Homocysteine Levels in Alcoholism: The Franconian Alcoholism Research Studies (FARS)". [en.wikipedia.org]

[…] levels without an increased vascular risk. [bloodjournal.org]

Classic Homocystinuria

homocysteine, methylmalonic acid Renal insufficiency • Increased homocysteine Pregnancy Nutritional folic acid deficiency Drug related Isonicotinic acid hydrazide therapy [academic.oup.com]

CH is associated with significantly increased serum levels of homocysteine and methionine and low concentrations of cysteine. [symptoma.com]

Diagnosis[edit] The term homocystinuria describes an increased excretion of the thiol amino acid homocysteine in urine (and incidentally, also an increased concentration in [en.wikipedia.org]

Homocystinuria due to Methylene Tetrahydrofolate Reductase Deficiency

This gene variation was associated with increased levels of homocysteine. [medscitechnol.com]

16 Second, increasing the alternate pathway for remethylation of homocysteine is expected to increase methionine by remethylating homocysteine. [nature.com]

Another common MTHFR variant, 1298A>C (NM_005957.4:c.1286A>C, rs1801131), does not cause increased homocysteine levels in heterozygous or homozygous individuals, but combined [ncbi.nlm.nih.gov]

Hereditary Factor II Deficiency

A quantitative assessment of plasma homocysteine as a risk factor for vascular disease: probable benefits of increasing folic acid intakes. [revistascientificas.una.py]

Congenital Vitamin B12 Deficiency

Deficiency of vitamin B 12 or folic acid can lead to increased homocysteine levels. Information from Stabler SP. [aafp.org]

Homocysteine levels were increased while vitamin B12 levels were decreased, and methylmalonic acid levels were elevated. [epostersonline.com]

In this reaction, a deficiency of vitamin B 12 or folic acid may lead to increased homocysteine levels. View/Print Figure FIGURE 1. [aafp.org]

Wright-Dyck Syndrome

Preoperative oral B vitamins prevent nitrous oxide-induced postoperative plasma homocysteine increases. Anesth Analg 2001;93:1507-10.. View abstract. [medlineplus.gov]

The responsiveness of plasma homocysteine to small increases in dietary folic acid: a primary care study. Eur.J Clin.Nutr 1998;52:407-411. View abstract. [medlineplus.gov]

Homocysteine increases as folate decreases in plasma of healthy men during short-term dietary folate and methyl group restriction. J Nutr 1994;124:1072-1080. [medlineplus.gov]

Transcobalamin 1 Deficiency

Deficiency of vitamin B 12 or folic acid can lead to increased homocysteine levels. Information from Stabler SP. [aafp.org]

Diagnostic biomarkers for B12 status include decreased levels of circulating total B12 and transcobalamin-bound B12, and abnormally increased levels of homocysteine and methylmalonic [natureasia.com]

Increased total homocysteine (tHcy) is under intense investigation as a risk factor for vascular disease and stroke ( 32 ) as well as for neural tube defects ( 33 ). [pnas.org]

Homocystinuria without Methylmalonic Aciduria Type cblG

Methionine synthase deficiency is thus associated with increased serum and tissue levels of homocysteine. [symptoma.com]

[symptoma.com] psychiatrical Suggestibility While an increased concentration of homocysteine in amniotic fluid may indicate a number of remethylation and transsulfuration [symptoma.com]

The pathogenesis of thrombotic microangiopathy is related to the increase of plasma methylmalonic acid and homocysteine levels. [revistanefrologia.com]

Homocystinuria with Methylmalonic Aciduria Type cblD

In patients suffering from inherited conditions that interfere with the conversion of homocysteine to methionine, blood and tissue levels of homocysteine are increased while [symptoma.com]

Patient Information The term " homocystinuria " refers an increased excretion of homocystine in the urine. [symptoma.com]

The pathogenesis of thrombotic microangiopathy is related to the increase of plasma methylmalonic acid and homocysteine levels. [revistanefrologia.com]

Homocystinuria without Methylmalonic Aciduria Type cblE

In patients suffering from inherited conditions that interfere with the conversion of homocysteine to methionine, blood and tissue levels of homocysteine are increased while [symptoma.com]

Diagnosis[edit] The term homocystinuria describes an increased excretion of the thiol amino acid homocysteine in urine (and incidentally, also an increased concentration in [en.wikipedia.org]

The pathogenesis of thrombotic microangiopathy is related to the increase of plasma methylmalonic acid and homocysteine levels. [revistanefrologia.com]

Vitamin B6 Deficiency

B6 deficiency can also be associated with an increased C-Reactive Protein (CRP) independent of homocysteine levels. [paulaowens.com]

Increased homocysteine levels have been linked with several health issues, most notably heart disease and stroke, as well as Alzheimer’s disease. [healthline.com]

Methylmalonic Acidemia

Some are associated with increased homocysteine. Discussion here relates to all forms. [mmaresearch.com]

Affected patients have increased methylmalonic acid and homocysteine in body fluids and can have visual and neurological problems. [genome.gov]

[…] total homocysteine with normal or decreased methionine. [ncbi.nlm.nih.gov]

Folate-Deficiency Anemia

Blood homocysteine will be found increased, above the reference range of 5-16 mmol/L, but it can be influenced by other factors, like kidney disease. [symptoma.com]

You get Macrocytic/Megaloblastic Anemia with Hypersegmented Neutrophils and increased Homocysteine levels. [stomponstep1.com]

These assays are helpful in the differential diagnosis with B12 deficiency, which is associated with increases in both serum homocysteine and methylmalonic acid. [clinicaladvisor.com]

Vitamin B Deficiency

During cobalamin deficiency, methylmalonic acid and homocysteine levels increase in the blood. [symptoma.com]

Deficiency of vitamin B 12 or folic acid can lead to increased homocysteine levels. Information from Stabler SP. [aafp.org]

Factor II Mutation

This is associated with increased plasma prothrombin levels. Increased plasma homocysteine levels is another important risk factor for venous thrombosis. [ayassbioscience.com]

The risk of venous thrombosis increases exponentially in patients with more than one risk factor, including age, surgery, oral contraceptive use, pregnancy, elevated homocysteine [labcorp.com]

Hyperhomocystinemia/MTHFR Homocysteine is an amino acid that may accumulate in the body under certain conditions and cause enhanced clot formation via stimulated increase [newyorkfertilityservices.com]

Methylmalonic Acidemia with Homocystinuria Type cblC

While increased homocysteine concentrations and impaired methyl group metabolism may contribute to disease-related complications, the characteristic macular and retinal degeneration [ncbi.nlm.nih.gov]

In patients suffering from inherited conditions that interfere with the conversion of homocysteine to methionine, blood and tissue levels of homocysteine are increased while [symptoma.com]

The pathogenesis of thrombotic microangiopathy is related to the increase of plasma methylmalonic acid and homocysteine levels. [revistanefrologia.com]

Hereditary Hypercarotenemia and Vitamin A Deficiency

[…] blood homocysteine levels; increases risk of atherosclerosis, heart disease, stroke; megaloblastic/macrocytic anemia (large immature red blood cells w/ low O2 carrying capacity [quizlet.com]

[…] acid synthesis; skin lesions; immune system weakness; anemia (inability to synthesize heme); seizures (inability to synthesize certain NT) also no effects of deficiency increases [quizlet.com]

Disorder of Sulfur-Bearing Amino Acid Metabolism

Homocystinuria represents a group of hereditary metabolic disorders characterized by an accumulation of homocysteine in the serum and an increased excretion of homocysteine [dictionnaire.sensagent.leparisien.fr]

[…] levels of homocysteine and methionine. [medicalhomeportal.org]

Platelet-Type Bleeding Disorder 12

Excessive homocysteine increases the risk of undesirable clotting and blood vessel constriction. [newstartclub.com]

Elevated homocysteine has been associated with a 60% increase in venous thrombosis risk for each 5 µmol/L increase in concentration (den Heijer 2005). [lifeextension.com]

Low intake of both vitamin B12 and folic acid increases the risk for elevated homocysteine levels. [newstartclub.com]

Macrocytic Anemia

B12-IF complex is absorbed in ileum. homocysteine: -what do elevated levels of this increase risk of? -what anemias are there increased homocysteine? [brainscape.com]

Finally, recall that the elevation of both metabolites cannot rule out a combined vitamin B12 and folate deficiency Isolated increase in serum methylmalonic acid and/or homocysteine [cancertherapyadvisor.com]

Due to these functions, vitamin B12 deficiency results in increased homocysteine and methylmalonic acid in the blood. [lecturio.com]