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4,635 Possible Causes for homologous

  • Acute Gastroenteritis

    Sequencing of a portion of the capsid gene and the ORF1/ORF2 overlap was used to assess DNA sequence homology, phylogeny, and recombination using pairwise alignments, MEGA[] One of the mechanisms that drives the evolution and emergence of new variants of NoV is homologous recombination.[] Homology and phylogenic analysis of a portion of the capsid region for GII NoV isolates collected during outbreaks in Hubei showed that the isolates had a very high sequence[]

  • Influenza

    Heterologous mean HI titers were normalized to mean homologous HI titers (mean heterologous titers/mean homologous titers).[] Mice are protected against an infection with homologous or heterologous influenza A virus after vaccination with a preparation containing complete M2 protein expressed in[] Relative mean HI titers were calculated by normalizing mean heterologous HI titers to mean homologous HI titers (mean heterologous HI titer/mean homologous HI titer).[]

  • Osteoporosis

    An orphan nuclear receptor, estrogen receptor–related receptor (ERR ), with sequence homology to ER and ERß, is also present in bone cells ( 22 ).[]

  • Infectious Mononucleosis

    The regions of homology between the targeting vector and the wild-type genome are indicated (hatched line).[] Several genes including ISG20 (interferon stimulated gene), DNAJB2 (DnaJ [Hsp40] homolog and CD99), CDK8 (cyclin-dependent kinase 8), E2F2 (E2F transcription factor 2), CDK8[] This peptide sequence has been found to be highly homologous to a peptide in EBNA-1 [ 13 ].[]

  • Meningitis

    Williams AFGagnon J Neuronal cell thy-1 glycoprotein: homology with immunoglobulin. Science. 1982;216696- 703 Google Scholar Crossref 148.[]

  • Idiopathic Pulmonary Fibrosis

    Hieshima K, Imai T, Baba M, Shoudai K, Ishizuka K, Nakagawa T et al (1997) A novel human CC chemokine PARC that is most homologous to macrophage-inflammatory protein-1 alpha[]

  • Tuberculosis

    A crtB homolog essential for photochromogenicity in Mycobacterium marinum : Isolation, characterization, and gene disruption via homologous recombination. J.[] This may be due to a high homology of the respective gene sequences to comparable counterparts in the other mycobacterial species.[] Gene replacement through homologous recombination in Mycobacterium intracellulare . J. Bacteriol. 177 , 6100–6105. PubMed Google Scholar 29. Marklund, B.[]

  • LIG4 Syndrome

    LIG4 syndrome is conferred by hypomorphic mutations in DNA ligase IV, an essential component of DNA non-homologous end-joining (NHEJ), and is associated with pancytopaenia[] […] retardation, low birth weight, dysmorphic facial findings, immunodeficiency, pancytopenia, and radiosensitivity due to impaired repair of DNA double-strand breaks by non-homologous[] The resulting defect of DNA ligase IV, a component of the classical non-homologous end-joining (NHEJ) pathway, affects the major mechanism of DNA double-strand break repair[]

  • Acromegaly

    This latter gene (a securin homolog) is over-expressed in functional pituitary tumors, which could lead to aneuploidy [ 45 ]; the degree of over-expression correlates with[]

  • Tuberous Sclerosis Type 2

    Two of the newly identified genes represent human homologs for rat and murine genes identified previously.[] In addition, we have isolated 43 exon traps that do not map to our existing cDNAs or PCR products and have no homology to sequences in the data bases.[] We have obtained cDNAs or RT-PCR products from eight novel genes, with sequences from seven of these genes having homology to sequences in the data bases.[]

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