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166 Possible Causes for Howell-Jolly Bodies

  • Pernicious Anemia

    The onset of pernicious anemia usually is insidious and vague. The classic triad of weakness, sore tongue, and paresthesias may be elicited but usually is not the chief symptom complex. Typically, medical attention is sought because of symptoms suggestive of cardiac, renal, genitourinary, gastrointestinal, infectious,[…][]

  • Leukemia

    Article Navigation Department of Hematopathology, The University of Texas M.D. Anderson Cancer Center, Houston Search for other works by this author on: Jose R. Valbuena, MD Department of Hematopathology, The University of Texas M.D. Anderson Cancer Center, Houston Search for other works by this author on:[…][]

  • Autoimmune Hemolytic Anemia

    In both panels, HowellJolly bodies (asterisks) are indicative of asplenia. Table 1. Table 1.[]

  • Folate-Deficiency Anemia

    Multinucleate RBCs, abnormal karyorrhexis, increased pyknosis, and Howell-Jolly bodies ( right) may be seen.[]

  • Acute Leukemia

    Other features are; fragmentation, Howell-Jolly bodies, ring sideroblast, megaloblastic and dyserythropoiesis changes are common.[]

  • Cooley's Anemia

    Abstract Hepatitis C infection is common in patients receiving life-long blood transfusion therapy. Interferon-alpha induces long-term viral clearance in 25-30% of patients suffering from Cooley's anemia. Ribavirin, an orally active guanoside analogue together with interferon-alpha produces a sustained response in up[…][]

  • Asplenia Syndrome

    Howell-Jolly bodies were found in their peripheral blood smear. The barium examinations of gastrointestinal tract showed intestinal obstruction and malrotation.[] Abstract Asplenia was suspected in one patient with combined immunodeficiency syndrome and 5 with congenital cardiac anomalies who had Howell-Jolly bodies on peripheral blood[] Both presented with the severe cardiovascular anomalies found in this syndrome and had Howell-Jolly bodies in peripheral blood smears.[]

  • Acute Lymphoblastic Leukemia

    Definition Acute lymphoblastic leukemia (ALL) is a cancer of the white blood cells in the bone marrow. The white blood cells (lymphocytes) grow in the bone marrow, then travel throughout the body to fight infections. ALL also causes the bone marrow to make too many of these cells. The overgrowth makes it difficult[…][]

  • Thalassaemia-Haemoglobin C Disease

    […] poikilocytosis Target cells, ovalocytes, occasional fragmented red blood cells, basophilic stippling, increased polychromatophilic cells (but insufficient for the degree of anemia), Howell-Jolly[] Nucleated red cells and Howell-Jolly bodies are often present. The total WBC count is elevated to 12,000-20,000/cmm, with a predominance of neutrophils.[] As the spleen becomes compromised with repeated infarctions, Howell-Jolly bodies are also seen. Several factors can lead to crises in sickle cell disease (Table 3).[]

  • Splenectomy

    - A dictionary of medical eponyms Related people Justin Marie Jolly William Henry Howell Spherical granules, 1-2 µ, seen in erythrocytes in slides of stained blood.[] Splenectomy patients typically have Howell-Jolly bodies and less commonly Heinz bodies in their blood smears.[] Howell-Jolly bodies appeared transiently after surgery in 19 of 40 patients.[]

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