Create issue ticket

183 Possible Causes for Howell-Jolly Bodies

  • Splenectomy

    Often, Howell-Jolly bodies on peripheral blood film give an important clue to diagnosing hyposplenism.[patient.info] Splenectomy patients typically have Howell-Jolly bodies [5] [6] and less commonly Heinz bodies in their blood smears. [7] Heinz bodies are usually found in cases of G6PD ([en.wikipedia.org] Its “pitting” function removes cellular inclusions like Heinz and Howell Jolly bodies without destruction of erythrocytes.[ncbi.nlm.nih.gov]

  • Autoimmune Hemolytic Anemia

    In both panels, HowellJolly bodies (asterisks) are indicative of asplenia. Table 1. Table 1.[nejm.org]

  • Folate-Deficiency Anemia

    Multinucleate RBCs, abnormal karyorrhexis, increased pyknosis, and Howell-Jolly bodies ( right) may be seen.[med-ed.virginia.edu]

  • Asplenia Syndrome

    Both presented with the severe cardiovascular anomalies found in this syndrome and had Howell-Jolly bodies in peripheral blood smears.[ncbi.nlm.nih.gov] Howell-Jolly bodies were found in their peripheral blood smear. The barium examinations of gastrointestinal tract showed intestinal obstruction and malrotation.[ncbi.nlm.nih.gov] Asplenia was suspected in one patient with combined immunodeficiency syndrome and 5 with congenital cardiac anomalies who had Howell-Jolly bodies on peripheral blood smears[ncbi.nlm.nih.gov]

  • Acute Leukemia

    Other features are; fragmentation, Howell-Jolly bodies, ring sideroblast, megaloblastic and dyserythropoiesis changes are common.[intechopen.com] . • Howell-Jolly bodies, ring sideroblast, megaloblastoid and dyserythropoietic changes • Coarse positivity of PAS • IHC: glycophorin A 33.[slideshare.net]

  • Thalassaemia-Haemoglobin C Disease

    […] poikilocytosis Target cells, ovalocytes, occasional fragmented red blood cells, basophilic stippling, increased polychromatophilic cells (but insufficient for the degree of anemia), Howell-Jolly[clinlabnavigator.com] -Heinz bodies -target cells -Howell-Jolly bodies -leukocytosis Sickle gene offers some protection against malaria What is the probable etiologic association between malaria[quizlet.com] Nucleated red cells and Howell-Jolly bodies are often present. The total WBC count is elevated to 12,000-20,000/cmm, with a predominance of neutrophils.[ndri.com]

  • Anemia of Chronic Disease

    Pappenheimer bodies (iron granules) are variably present in the erythrocytes. Together with Howell-Jolly bodies, these reflect associated splenic dysfunction.[nataonline.com]

  • Sickle Cell Thalassemia Disease

    The peripheral blood smear results demonstrate normocytic, normochromic RBCs, the presence of nucleated RBCs (NRBCs), polychromasia, sickle cells, target cells, Howell-Jolly[academic.oup.com] bodies, and Pappenheimer bodies.[academic.oup.com]

  • Splenic Cyst

    On follow up the splenunculus had increased to normal splenic size and there was no evidence of Howell-Jolly bodies, suggesting normal splenic function.[ncbi.nlm.nih.gov]

  • Hereditary Koilonychia

    Abnormality in transfer of iron out of storage Reduced erythropoietin What are Howell-Jolly bodies are indicative of? Splenectomy or splenic atrophy (ex.[quizlet.com] Labs: Sickling test and Hb electrophoresis (look for HbS) PBS: Sickle cells, Howell-Jolly Bodies CBC: reticulocyte count What are the acute complications you can expect in[quizlet.com]

Further symptoms

Similar symptoms