Hydrops Fetalis: Causes & Reasons

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Possible Causes for Hydrops Fetalis

Fetal Erythroblastosis

Extended hydrops fetalis can inhibit lung growth and contribute toheart failure. [faqs.org]

Hydrops fetalis and anemia can also contribute to heart problems. [medical-dictionary.thefreedictionary.com]

Hydrops fetalis (Fetal edema). A survey. Clin. Pediatr. 19 :334–339, 1980. [link.springer.com]

Mucopolysaccharidosis

Keywords Live Birth Consanguineous Parent Mucopolysaccharidosis Hunter Syndrome Hydrops Fetalis These keywords were added by machine and not by the authors. [doi.org]

Three cases of non-immune hydrops fetalis born to consanguineous parents were thought to be due to beta-glucuronidase deficiency (MPS VII) on the basis of placental histology [ncbi.nlm.nih.gov]

The severe neonatal form is the most common type of this syndrome, characterized by hydrops fetalis (abnormal accumulation of fluid in various tissues of the body) and dysmorphic [news-medical.net]

Gaucher Disease Type 2

Features of the perinatal lethal form can include extensive swelling caused by fluid accumulation before birth (hydrops fetalis); dry, scaly skin (ichthyosis) or other skin [slideshare.net]

fetalis ( 9745785 ) Physiopathology As a result, glucocerebroside accumulates principally in the phagocytic cells of the body but in some forms also in the central nervous [humpath.com]

Kupffer cells with striated or corrugated cytoplasm Ultrastructure gaucher cells with membrane-bound spindled, tubular inclusions Variants fetal Gaucher disease ( 9745785 ) hydrops [humpath.com]

Gaucher Disease

The most distinct features of perinatal-lethal Gaucher disease are non-immune hydrops fetalis, in utero fetal demise and neonatal distress. [ncbi.nlm.nih.gov]

A severe neonatal form can present in utero or perinatally with hydrops fetalis, congenital ichthyosis, or both. [emedicine.medscape.com]

Features of the perinatal lethal form can include extensive swelling caused by fluid accumulation before birth (hydrops fetalis); dry, scaly skin (ichthyosis) or other skin [ghr.nlm.nih.gov]

Erythema Infectiosum

In pregnant women, however, it may be associated with fetal death and nonimmune hydrops fetalis. [ncbi.nlm.nih.gov]

Fetal complications include hydrops fetalis and intrauterine fetal demise. [bestpractice.bmj.com]

Hydrops fetalis and fetal death are complications of intrauterine parvovirus B19 infection. [ncbi.nlm.nih.gov]

Mucopolysaccharidosis Type 7

The severe form of MPS 7 can uniquely present at birth with hydrops fetalis (severe generalized edema). [ultragenyx.com]

Most babies with hydrops fetalis are stillborn or die soon after birth. [ghr.nlm.nih.gov]

More than half of infants with hydrops fetalis do not survive beyond early infancy. Some adults with MPS 7 can have a less severe physical or skeletal disease. [ultragenyx.com]

Alpha-Thalassemia

They had a healthy non-thalassemic daughter from the first pregnancy but the second pregnancy ended unexpectedly with Hb Bart's hydrops fetalis. [ncbi.nlm.nih.gov]

With all the four cases having the gestational age range from 18 to 27 weeks, three showed hydrop fetalis. [ncbi.nlm.nih.gov]

Expectant mothers also experience pregnancy complications, when carrying an embryo with hydrops fetalis. [symptoma.com]

Pyruvate Kinase Deficiency

The authors report a case of hydrops fetalis due to severe pyruvate kinase deficiency, the most unusual clinical manifestation of this disease. [ncbi.nlm.nih.gov]

Prompt fetal diagnosis of pyruvate kinase deficiency is feasible and allows better management of hydrops fetalis due to this disorder. [ncbi.nlm.nih.gov]

fetalis). [rarediseases.info.nih.gov]

Mucolipidosis

Type II patients may also present with a congenital-onset form associated with ascites and hydrops fetalis prenatally, an infantile-onset form with the absence of symptoms [genedx.com]

The more severe subtype may induce hydrops fetalis or manifest soon after birth. Affected individuals present dysmorphic facial features reminiscent of Hurler syndrome. [symptoma.com]

Investigation of lysosomal storage diseases in nonimmune hydrops fetalis. Prenat Diagn. 2004 Aug. 24(8):653-7. [Medline]. Cibis GW, Tripathi RC, Harris DJ. [emedicine.medscape.com]

Noonan Syndrome

We report the case of a 4 y old female with a history of polyhydramnios, hydrops fetalis and bilateral congenital chylothorax. [raredisorders.imedpub.com]

We describe an infant prenatally diagnosed with hydrops fetalis ultimately found to have Noonan syndrome (NS). [ncbi.nlm.nih.gov]

fetalis, increased nuchal translucency, polyhydramnios, renal anomalies Per obstetrician's recommendation Chorionic villus sampling or amniocentesis for diagnosis if indicated [aafp.org]

Mucopolysaccharidosis Type 4

The most severe form is characterized by hydrops fetalis and premature or very early death. [centogene.com]

In its rarest form, Sly syndrome causes children to be born with hydrops fetalis, in which extreme amounts of fluid are retained in the body. [en.wikipedia.org]

Mucopolysaccharidosis Type 1

In rare cases, some newborn infants with Sly syndrome may experience abnormal accumulation of fluid in various tissues of the body (hydrops fetalis). [rarediseases.org]

The most severe form is characterized by hydrops fetalis and premature or very early death. [centogene.com]

Niemann-Pick Disease Type C

Pathogenic variants of the NPC1 or NPC2 genes yield highly variable phenotypes with a time course that ranges from fetal onset (i.e., hydrops fetalis) to progressive dementia [ncbi.nlm.nih.gov]

Hepatic insufficiency may cause hydrops fetalis. [symptoma.com]

The presence of perinatal hydrops fetalis or family history of a sibling with fetal ascites is a possible indicator of lysosomal storage disease. [hindawi.com]

Mirror Syndrome

Keywords Mirror syndrome Ballantyne syndrome Hydrops Fetalis anemia Maternal edema Authors Rafał Iciek Maciej Brązert Andrzej Klejewski Marek Pietryga Jacek Brązert [journals.viamedica.pl]

Since the most common cause for the development of hydrops fetalis is preeclampsia, we thought it could be important to identify clinical differences that could help in a [hindawi.com]

Keywords Mirror syndrome, Ballantyne syndrome, Hydrops Fetalis, anemia, Maternal edema About this article Title Ballantyne syndrome (the Mirror Syndrome) associated with severe [journals.viamedica.pl]

Generalized Arterial Calcification of Infancy

[oncotarget.com] Fetus Hydrops Fetalis [doi.org] Fetus Hydrops Fetalis We report the case of a 32-week-old infant with hydrops fetalis and heart failure who died at 4 days [symptoma.com]

[doi.org] Fetus Hydrops Fetalis We report the case of a 32-week-old infant with hydrops fetalis and heart failure who died at 4 days of age. [symptoma.com]

To our knowledge only few cases of GACI with hydrops fetalis were reported (1). Case report: We report on a female infant presented with hydrops fetalis. [thieme-connect.com]

Generalized Arterial Calcification of Infancy 2

[doi.org] Fetus Hydrops Fetalis We report the case of a 32-week-old infant with hydrops fetalis and heart failure who died at 4 days of age. [symptoma.com]

[oncotarget.com] Fetus Hydrops Fetalis [doi.org] Fetus Hydrops Fetalis We report the case of a 32-week-old infant with hydrops fetalis and heart failure who died at 4 days [symptoma.com]

To our knowledge only few cases of GACI with hydrops fetalis were reported (1). Case report: We report on a female infant presented with hydrops fetalis. [thieme-connect.com]

Generalized Arterial Calcification of Infancy 1

[oncotarget.com] Fetus Hydrops Fetalis [doi.org] Fetus Hydrops Fetalis We report the case of a 32-week-old infant with hydrops fetalis and heart failure who died at 4 days [symptoma.com]

[doi.org] Fetus Hydrops Fetalis We report the case of a 32-week-old infant with hydrops fetalis and heart failure who died at 4 days of age. [symptoma.com]

To our knowledge only few cases of GACI with hydrops fetalis were reported (1). Case report: We report on a female infant presented with hydrops fetalis. [thieme-connect.com]

Short Rib-Polydactyly Syndrome Type Beemer-Langer

fetalis, facial and visceral abnormalities, short ribs, and short limbs without polydactyly. [bioportal.bioontology.org]

[…] bone, brain and kidney, and related phenotypes are macrocephaly and hypertelorism Disease Ontology : 12 A syndrome that results in multiple congenital anomalies, including hydrops [malacards.org]

fetalis X-ray Short horizontal ribs Trident-shaped pelvis Square iliac wings Horizontal acetabular roofs with medial spurs Proximal femoral ossification centers present at [fetalultrasound.com]

Congenital Syphilis

Early, intrauterine infection may not even be symptomatic at birth, but can also lead to preterm birth, hydrops fetalis or still birth. [symptoma.com]

Congenital Syphilis Syphilis in pregnancy increases the risk of adverse outcomes, including pre-term delivery, low birth weight, non-immune hydrops fetalis, intrauterine growth [medicalreview.columbia.edu]

TABLE 3 Common features of congenital syphilis* Feature Usual timing Details Spontaneous abortion/ stillbirth/ hydrops fetalis Any gestation Occurs in approximately 40% of [cps.ca]

Hypercholesterolemia

Non-immune hydrops fetalis Non-immune hydrops fetalis is now the most common type of hydrops fetalis. [healthline.com]

What are the symptoms of hydrops fetalis? Symptoms of hydrops fetalis can occur during pregnancy or after the baby is born. [childrenshospital.org]

Home Diseases Hydrops fetalis Title Other Names: Idiopathic hydrops fetalis; Hydrops fetalis nonimmune; Familial non-immune hydrops fetalis Hydrops fetalis is a serious condition [rarediseases.info.nih.gov]

Hydropneumothorax

Non-immune hydrops fetalis Non-immune hydrops fetalis is now the most common type of hydrops fetalis. [healthline.com]

What are the symptoms of hydrops fetalis? Symptoms of hydrops fetalis can occur during pregnancy or after the baby is born. [childrenshospital.org]

Neonatal Respiratory Distress Syndrome

Non-immune hydrops fetalis Non-immune hydrops fetalis is now the most common type of hydrops fetalis. [healthline.com]

What are the symptoms of hydrops fetalis? Symptoms of hydrops fetalis can occur during pregnancy or after the baby is born. [childrenshospital.org]

When Rh(D) immune globulin is administered appropriately though, only 10% of contemporary hydrops fetalis cases result from this cause. [fetalhealthfoundation.org]

Chylothorax

Morbidity of congenital chylothorax (CC) is high, and prognosis is very poor if CC is associated with hydrops fetalis. [ncbi.nlm.nih.gov]

A 35-week preterm who presented with massive congenital chylothorax complicated with hydrops fetalis. [jcnonweb.com]

We report the case of a 4 y old female with a history of polyhydramnios, hydrops fetalis and bilateral congenital chylothorax. [raredisorders.imedpub.com]

Congenital Dyserythropoietic Anemia

Fetalis/diagnosis* Hydrops Fetalis/etiology* Hydrops Fetalis/therapy Infant Infant, Newborn Jaundice, Neonatal/diagnosis Jaundice, Neonatal/etiology Jaundice, Neonatal/therapy [ncbi.nlm.nih.gov]

Hydrops fetalis is rarely caused by congenital dyserythropoietic anemia (CDA). We report a patient with hydrops fetalis as a result of severe anemia. [ncbi.nlm.nih.gov]

Congenital dyserythropoietic anemia should be considered in the differential diagnosis of hydrops fetalis presenting with a very severe anemia and a skeletal abnormality of [ncbi.nlm.nih.gov]

Solid Ovarian Teratoma

Complications may include ovarian torsion testicular hydrops fetalis. [amerigau.com]

Fetalis, with Gracile Bones and Dysmorphic Features Oculoskeletodental Syndrome Odontomicronychial Dysplasia Odontoonychodermal Dysplasia Odontotrichoungual-Digital-Palmar [rgd.mcw.edu]

Potential complications in utero include polyhydramnios and tumor hemorrhage, which can lead to anemia and nonimmune hydrops fetalis. [csh.org.tw]

Hydrocephalus

What is hydrops fetalis? [childrenshospital.org]

Non-immune hydrops fetalis Non-immune hydrops fetalis is now the most common type of hydrops fetalis. [healthline.com]

What is hydrops fetalis? Hydrops fetalis is severe swelling (edema) in an unborn baby or a newborn baby. It is a life-threatening problem. [stanfordchildrens.org]

Hemoglobinopathy

Of the 664 patients represented, 163 (24.5%) were beta-thalassemia major carriers, 68 (10.2%) were hemoglobin Bart's hydrops fetalis carriers and, in total, 361 (54.4%) had [ncbi.nlm.nih.gov]

The estimated numbers of pregnancies each year in the Meizhou region, in which the fetus would be at risk for β thalassemia major or intermedia, Bart's hydrops fetalis, and [ncbi.nlm.nih.gov]

Death occurs in utero from Hb Bart’s hydrops fetalis. [mlo-online.com]

Tachyarrhythmia

Abstract In cases of non-immune hydrops fetalis caused by tachyarrhythmias, the transplacental passage of antiarrhythmic drugs may be hampered. [ncbi.nlm.nih.gov]

Assessment for the presence of congenital cardiac anomalies and for complications such has hydrops fetalis are recommoneded as part of routine sonographic assessment. [radiopaedia.org]

Secondary effects of fetal circulation can be additionally assessed by: ductus venosus flow assessment umbilical vein flow assessment development of hydrops fetalis Treatment [radiopaedia.org]

Congenital Chylothorax

To discuss a range of management techniques and supportive therapies for hydrops fetalis and CC. [ncbi.nlm.nih.gov]

fetalis and CC.PubMed and CINAHL were searched using the terms "hydrops fetalis," "congenital," "chylothorax," "neonate," and "preterm." [scholars.duke.edu]

It is a common cause of unidentified hydrops fetalis. [kjp.or.kr]

Thalassemia

KEYWORDS: Hb Bart’s hydrops fetalis; ultrasound; α-Globin gene; α-thalassemia (α-thal) [ncbi.nlm.nih.gov]

KEYWORDS: Direct whole blood PCR; Hemoglobin Bart’s hydrops fetalis; α0-thalassemia [ncbi.nlm.nih.gov]

Neonates with Hb Bart's hydrops fetalis usually die in the perinatal period. [orpha.net]