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26 Possible Causes for Hyperactivity, Hypothyroidism, Wide Space Between the First and Second Toe

  • Down Syndrome

    Among the subclinical hypothyroidism group, 25 (73.5%) had transient hypothyroidism and 9 (26.5%) persistent hypothyroidism.[ncbi.nlm.nih.gov] Behavior suggestive of attention-deficit/hyperactivity disorder is often seen in childhood.[merckmanuals.com] A wide space, often with a deep fissure between the first and second toes, is also common.[dx.doi.org]

  • Dubowitz Syndrome

    There can be many associated heath problems including hypothyroidism (an underactive thyroid), heart defects, hypotonia and eye problems.[bertsbigadventure.org] […] disorder Attention deficit Attention deficit disorder Attention deficit-hyperactivity disorder Attention deficits Childhood attention deficit/hyperactivity disorder [ more[rarediseases.info.nih.gov] In older patients, endocrine problems were common: hypogonadism, hypothyroidism, amenorrhea, and diabetes ( Table S5 ).[journals.plos.org]

  • Seckel Syndrome

    Synonym: pituitary dwarf. (05 Mar 2000) hypothyroid dwarf Dwarfism associated with lack of thyroid function. (05 Mar 2000) oil of dwarf pine needles Volatile oil from the[kmle.co.kr] Most children with Seckel syndrome are "friendly and pleasant" but "often hyperkinetic (hyperactive) and easily distracted." This disease is genetic.[medicinenet.com] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov]

  • Atelosteogenesis Type 2

    XY complete gonadal dysgenesis 46,XY partial gonadal dysgenesis Athyreosis Familial gestational hyperthyroidism Familial hyperthyroidism due to mutations in TSH receptor Hypothyroidism[csbg.cnb.csic.es] Ethylmalonic Aciduria Excessive Daytime Sleepiness Exostoses, Multiple, Type II Extrapyramidal Movement Disorder Fabry Disease Faciogenital Dysplasia with Attention Deficit Hyperactivity[sequencing.com] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov]

  • Ring Chromosome 10

    […] hypospadia, bifid scrotum, bilateral cryptorchidism, bilateral inguinal hernia, vesico-uretheral reflux (grade III), recurrent pulmonary and urinary infections, subclinical hypothyroidism[biomedsearch.com] , clinodactyly of V finger, normal mental/motor development, short attention span, hyperactive behaviour p22.3 q36.3 12431259 Edit 2 8922097_1 46, XY, r(7)(p22.3q36.3) [80%[chr7.org] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov]

  • Kleiner Holmes Syndrome

    Maternal antenatal history was uneventful except for subclinical hypothyroidism detected during gestation.[docksci.com] Attention deficit problems – with or without hyperactivity, anxiety, and aggression – can be seen in almost 8 out of 10 children.[epilepsy.com] […] gap between first and second toes Wide space between 1st, 2nd toes Wide space between first and second toes Widely spaced 1st-2nd toes Widely spaced first and second toes[rarediseases.info.nih.gov]

  • Familial Congenital Nasolacrimal Duct Obstruction

    Thyroid Problems What is hypothyroidism? What causes hypothyroidism? Who gets hypothyroidism? How does hypothyroidism cause disease? What are the common findings?[calvarypediatrics.com] […] hepatitis (1) Zoonoses (2) Mental health care (257) Acute stress disorder (5) Adjustment disorders (1) Aggression (1) Anxiety (9) Anxiety disorders (2) Attention-deficit/hyperactivity[innovations.ahrq.gov] space between first and second toes (sandal toes) clinodactyly of the fifth finger All of these are found in individuals without DS.[medicalhomeportal.org]

  • Short Stature due to Endocrine Disorder

    […] insulin-like growth factor type 1 deficiency Growth hormone insensitivity syndrome Laron syndrome Laron syndrome with immunodeficiency MULIBREY nanism Parastremmatic dwarfism Rare hypothyroidism[se-atlas.de] […] deficit disorder Attention deficit-hyperactivity disorder Attention deficits Childhood attention deficit/hyperactivity disorder [ more ] 0007018 Bilateral sensorineural hearing[rarediseases.info.nih.gov] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov]

  • Craniofrontonasal Dysplasia

    […] syndrome 1B Endothelin EDN3 Waardenburg syndrome IVb Hirschsprung's disease 4 Other DHH ( DHH XY gonadal dysgenesis ) BMP15 ( Premature ovarian failure 4 ) TSHB ( Congenital hypothyroidism[maria-online.com] […] or malfunction, or hormonalHP:0001852Sandal gapMP:0020157abnormal behavioral response to alcoholany anomaly in the behavioral response induced by alcohol, such as induced hyperactivity[pediascape.org] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov]

  • Cutis Laxa

    We report a newborn with autosomal recessive form of congenital cutis laxa, who had congenital hypothyroidism owing to isolated thyrotropin deficiency.[ncbi.nlm.nih.gov] Hyperactivity has also been reported in GO patients (Lisker et al. , 1979).[scielo.br] In hypothyroid subjects, the skin is dry, cold, and rough. The epidermis is hyperkeratotic, alopecia may develop, and there is diffuse myxedema [ 7 ].[karger.com]

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