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26 Possible Causes for Hyperactivity, Wide Space Between the First and Second Toe

  • Dubowitz Syndrome

    This autosomal recessive disorder is characterized by variable degrees of intrauterine and postnatal growth retardation, microcephaly, mild mental retardation, hyperactivity[ncbi.nlm.nih.gov] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] Further findings include hyperactivity, eczema, cryptorchidism in the affected males, and brachy-clinodactyly of the fifth fingers.[ncbi.nlm.nih.gov]

  • Seckel Syndrome

    Most children with Seckel syndrome are "friendly and pleasant" but "often hyperkinetic (hyperactive) and easily distracted." This disease is genetic.[medicinenet.com] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] Wide space between first and second toes Wide-spaced big toe Widely spaced 1st-2nd toes Widely spaced first and second toes Widened gap 1st-2nd toes Widened gap first and[rarediseases.info.nih.gov]

  • Down Syndrome

    In more rare cases, Down syndrome patients may be affected with hyperthyroidism, symptoms of which include breathing and sleeping difficulties, and hyperactivity.[symptoma.com] A wide space, often with a deep fissure between the first and second toes, is also common.[dx.doi.org] Behavior suggestive of attention-deficit/hyperactivity disorder is often seen in childhood.[merckmanuals.com]

  • Ring Chromosome 10

    , clinodactyly of V finger, normal mental/motor development, short attention span, hyperactive behaviour p22.3 q36.3 12431259 Edit 2 8922097_1 46, XY, r(7)(p22.3q36.3) [80%[chr7.org] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] Breakpoint #2Pubmed IDPatient ID Comments 1 12431259 46, XY, r(7)(p22.3q36.3). ish r(7pter , 7qtel , AHT-) intrauterine growth retardation, short stature, microcephaly, hyperactive[chr7.org]

  • Kleiner Holmes Syndrome

    Attention deficit problems – with or without hyperactivity, anxiety, and aggression – can be seen in almost 8 out of 10 children.[epilepsy.com] […] gap between first and second toes Wide space between 1st, 2nd toes Wide space between first and second toes Widely spaced 1st-2nd toes Widely spaced first and second toes[rarediseases.info.nih.gov] Hyperactivity and a decreased attention span are observed in as many as 80% of patients as well as rage, aggression, and anxiety.[en.wikipedia.org]

  • Atelosteogenesis Type 2

    He had difficulty in walking, mild proximal muscular hypotonia in the lower extremities and hyperactive deep tendon reflexes.[nature.com] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] Ethylmalonic Aciduria Excessive Daytime Sleepiness Exostoses, Multiple, Type II Extrapyramidal Movement Disorder Fabry Disease Faciogenital Dysplasia with Attention Deficit Hyperactivity[sequencing.com]

  • Growth Delay due to Insulin-Like Growth Factor I Resistance

    […] deficit disorder Attention deficit-hyperactivity disorder Attention deficits Childhood attention deficit/hyperactivity disorder [ more ] 0007018 Bilateral sensorineural hearing[rarediseases.info.nih.gov] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] Showing of 45 80%-99% of people have these symptoms Abnormal facial shape Unusual facial appearance 0001999 Attention deficit hyperactivity disorder Attention deficit Attention[rarediseases.info.nih.gov]

  • Craniofrontonasal Dysplasia

    […] or malfunction, or hormonalHP:0001852Sandal gapMP:0020157abnormal behavioral response to alcoholany anomaly in the behavioral response induced by alcohol, such as induced hyperactivity[pediascape.org] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] Craniofrontonasal Syndrome and a Mutation (p.G151S) in the EFNB1 Gene: Expanding the Phenotype. ( 27194971 ) Toral-LA pez J....Cuevas-Covarrubias S.A. 2016 5 Depression and hyperactivity[malacards.org]

  • Meningomyelocele

    Patients with spina bifida and hydrocephalus often display attention problems with up to 31% developing attention deficit hyperactive disorder (ADHD) at a very early age.[docdoc.com] space between first and second toes 11. ability to assume unusual positions Intracranial hemorrhage interventions 1. observation of increased intracranial pressure 2. head[quizlet.com] […] head 3. round face 4. flat nose 5. protruding tongue that interferes with sucking 6. mouth breathing 7. simian crease 8. short and thick hands 9. little finger curved 10. wide[quizlet.com]

  • Cutis Laxa

    Hyperactivity has also been reported in GO patients (Lisker et al. , 1979).[scielo.br] Other reported osteoarticular features are: a wide space between the first and second toes; talipes equinovarus; metatarsus adductus; genu recurvatum or genu valgum; flat[scielo.br] The patient has mental impairment with hyperactivity and attends a school for handicapped children.[scielo.br]

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