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75 Possible Causes for Hyperalgesia, Hyperesthesia, Lower Extremity Pain

  • Reflex Sympathetic Dystrophy

    Reflex sympathetic dystrophy is characterized by constant burning pain and hyperesthesia in an extremity. Lower extremities are usually affected.[ncbi.nlm.nih.gov] This disorder should be considered in any painful pelvic girdle syndrome or lower extremity pain. The hip is involved in 88% of cases.[ncbi.nlm.nih.gov] The serum concentration of noradrenaline was lower on the painful side than on the healthy side, and neurotropin, which has an antinociceptive effect to hyperalgesia, was[ncbi.nlm.nih.gov]

  • Spinal Cord Metastasis

    […] significant history of a high-grade urothelial carcinoma who presented with progressive back pain and concomitant weakness, grade 3-4/5 proximally and 0-1/5 distally, and distal hyperesthesia[ncbi.nlm.nih.gov] Case report This 59-year-old woman presented with a 2-month history of low back pain and right lower extremity pain.[nature.com] […] sensation in his right lower extremity.[ncbi.nlm.nih.gov]

  • Meralgia Paresthetica

    The general examination revealed mild obesity; the neurological examination of both patients is normal except for pain, hypo- or hyperesthesia on the side of the quadriceps[ncbi.nlm.nih.gov] extremity. 4 , 5 MP literally means thigh pain, and its clinical features are abnormal or decreased sensation and pain on the anterolateral side of the thigh.[synapse.koreamed.org] This condition is called opioid-induced hyperalgesia.[biotherapy-clinic.com]

  • Alcoholic Neuropathy

    Lettsome in 1787 when he noted hyperesthesia and paralysis in legs more than arms of patients. [1] Jackson has also been credited with describing polyneuropathy in chronic[en.wikipedia.org] As the condition progresses, additional signs may include: Weakness, pain, numbness or tingling that spreads to other parts of your upper or lower extremities Muscle spasms[promises.com] Alcoholic neuropathy involves coasting caused by damage to nerves that results from long term excessive drinking of alcohol and is characterized by spontaneous burning pain, hyperalgesia[ncbi.nlm.nih.gov]

  • Diabetic Peripheral Neuropathy

    And sural nerve dysfunction mainly presented as hyperesthesia under three frequencies.[ncbi.nlm.nih.gov] Individuals who develop DPN often experience severe, uncontrolled pain in the lower extremities, insensate feet, and decreased proprioceptive skills.[mdedge.com] Neuroreport 9 : 243 -247, 1998 Rodella L , Rezzani R, Corsetti G, Bianchi R: Nitric oxide involvement in the trigeminal hyperalgesia in diabetic rats.[clinical.diabetesjournals.org]

  • Erythromelalgia

    Many people complain that their feet are overly sensitive to touch (hyperesthesia) and can have varying degrees of burning pain. It can range from mild to disabling.[webmd.com] Erythromelalgia is a rare disorder associated with neuropathic pain that commonly affects the lower extremities. This pain is often refractory to multimodal treatment.[ncbi.nlm.nih.gov] […] had hyperalgesia on testing.[ncbi.nlm.nih.gov]

  • Diabetic Polyneuropathy

    The signs of damage to the peripheral neurons are hypoesthesia, hypoalgesia, hyperesthesia and hyperalgesia, decreased tendon reflexes, and, possibly, weakness and muscle[ncbi.nlm.nih.gov] To investigate the effect of decompression of nerves in the lower extremity in patients with painful diabetic polyneuropathy on static balance using a sensitive pressure mat[ncbi.nlm.nih.gov] At neurologic evaluation there is distal hypoesthesia/hyperesthesia in segments, initially in thermoalgesic sensitivity modalities.[scielo.br]

  • Hyperesthetic Thalamic Pain Syndrome

    Hyperesthesia Symptoms As aforementioned, in cutaneous hyperesthesia, the skin reacts overtly to any type of stimuli causing an increase in pain and tenderness.[patienthelp.org] The final diagnostic statement lists chronic pain syndrome and chronic lower back pain with acute exacerbation of lower back pain and lower extremity pain.[health-information.advanceweb.com] Hyperesthesia is further divided into hyperalgesia and allodynia.[brainscape.com]

  • Clonidine

    The diagnosis of CRPS was made if a) patients had at least four of these symptoms: allodynia, hyperesthesia, edema, vasomotor changes, pain with a burning quality, sudomotor[ncbi.nlm.nih.gov] Repeated lumbar sympathetic blockade (LSB) with local anesthetics is generally used in complex regional pain syndrome (CRPS) of the lower extremities if the initial block[ncbi.nlm.nih.gov] Hyperalgesia is normally an increase in the response to a painful stimulant. Opioid-induced hyperalgesia (OIH) is a situation frequently encountered in algology clinics.[ncbi.nlm.nih.gov]

  • Small-Fiber Neuropathy

    Small-fiber neuropathy manifests in a variety of different diseases and often results in symptoms of burning pain, shooting pain, allodynia, and hyperesthesia.[ncbi.nlm.nih.gov] Burning dysesthetic pain began in the lower back and progressed to all extremities 9 days following human papillomavirus vaccination.[ncbi.nlm.nih.gov] […] by negative sensory symptoms (thermal and pinprick hypoesthesia) reflecting peripheral deafferentation and positive sensory symptoms and signs (burning pain, allodynia, hyperalgesia[ncbi.nlm.nih.gov]

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