Create issue ticket

2,469 Possible Causes for Hyperbilirubinemia, Non-Hemolytic Unconjugated Hyperbilirubinemia, Psychomotor Development Delayed

  • Gilbert Syndrome

    Constitutional liver dysfunction Familial non-hemolytic non-obstructive jaundice Icterus intermittens juvenilis Low-grade chronic hyperbilirubinemia Unconjugated benign bilirubinemia[en.wikipedia.org] Hyperbilirubinemia is an important clinical sign that often indicates severe hepatobiliary disease of different etiologies.[ncbi.nlm.nih.gov] Tagged as: constitutional liver dysfunction, familial benign unconjugated hyperbilirubinaemia, familial non-hemolytic non-obstructive jaundice, Gilbert–Meulengracht syndrome[highrisklifeinsuranceagency.com]

    Missing: Psychomotor Development Delayed
  • Early Infantile Epileptic Encephalopathy Type 6

    We report on a patient who developed, from 5 months of age, multiple seizure types, including myoclonic, associated with severe psychomotor delay, leading to the diagnosis[ncbi.nlm.nih.gov] , resulting from exacerbated hemolysis) Chronic, non-immune hemolytic anemia High mean corpuscular hemoglobin concentration (MCHC) Presence of spherocytes in the peripheral[centogene.com] Over the years, he developed refractory epilepsy and was implanted with a vagus nerve stimulator at the age of 19.[ncbi.nlm.nih.gov]

  • Crigler-Najjar Syndrome Type 1

    Mutations in the UGT1A1 gene cause Crigler-Najjar syndrome (CN), which causes non-hemolytic unconjugated hyperbilirubinemia, and is categorized as CN1 and CN2 according to[ncbi.nlm.nih.gov] This study demonstrated the efficacy of hepatic progenitor cells to manage hyperbilirubinemia in these patients.[ncbi.nlm.nih.gov] Crigler-Najjar (CN) syndrome is a rare autosomal recessive inherited disorder characterized by non-hemolytic, unconjugated hyperbilirubinemia.[ncbi.nlm.nih.gov]

    Missing: Psychomotor Development Delayed
  • Brandt Syndrome

    Icterus intermittens juvenilis; Low-grade chronic hyperbilirubinemia; Familial non-hemolytic-non-obstructive jaundice; Constitutional liver dysfunction; Unconjugated benign[medlineplus.gov] Icterus intermittens juvenilis; Low-grade chronic hyperbilirubinemia; Familial non-hemolytic-non-obstructive jaundice; Constitutional liver dysfunction; Unconjugated benign[medlineplus.gov]

  • Leigh's Disease

    When hyperbilirubinemia is not treated with phototherapy, the bilirubin can accumulate in the basal ganglia and cause lesions similar to those seen in Leigh syndrome.[en.wikipedia.org] delay – a delayed development of intellect and motor ability Dystonia – uncontrollable muscle contractions causing repetitive twisting movements Epilepsy - The condition[lhsc.on.ca] […] groups have been affected, a common mutation has been found in Faroese people (an ethnic group with a population of about 25 000 living Scandinavia) Symptoms Neurological: Psychomotor[lhsc.on.ca]

    Missing: Non-Hemolytic Unconjugated Hyperbilirubinemia
  • Septo-Optic Dysplasia

    Neurological examination revealed axial laxity, psychomotor development delay, difficulties in keeping eyes fixed as well as rotary and horizontal nystagmus.[ncbi.nlm.nih.gov] The patient suffered in neonatal life from severe hypoglycemia, conjugated hyperbilirubinemia and nystagmus.[ncbi.nlm.nih.gov] We report a 6-month-old female patient who presented absent visual fixation since 4 months of age and delayed psychomotor development.[ncbi.nlm.nih.gov]

    Missing: Non-Hemolytic Unconjugated Hyperbilirubinemia
  • Thalassemia

    psychomotor development, intellectual disability, and characteristic facial features (summary by O'Rawe et al., 2015).[ncbi.nlm.nih.gov] Indirect hyperbilirubinemia, elevated lactate dehydrogenase levels, and reduced haptoglobin are all consistently seen with hemolytic anemia.[emedicine.medscape.com] The skin may show pallor from anemia and jaundice from hyperbilirubinemia, and the skull and other bones may be deformed secondary to erythroid hyperplasia with intramedullary[emedicine.medscape.com]

    Missing: Non-Hemolytic Unconjugated Hyperbilirubinemia
  • Pyruvate Kinase Deficiency

    It constitutes one of the common causes of hereditary non-spherocytic hemolytic anemia.[ncbi.nlm.nih.gov] We report an infant with neonatal hyperbilirubinemia due to pyruvate kinase deficiency.[ncbi.nlm.nih.gov] Subcommittee on Hyperbilirubinemia, American Academy of Pediatrics.[nature.com]

    Missing: Psychomotor Development Delayed
  • Farber Disease

    Polyposis familial myxoma Familial Nephropathy Associated with Hyperuricemia Familial Nephropathy with Gout Familial Nonhemolytic Jaundice Familial Nonhemolytic Unconjugated Hyperbilirubinemia[healthmedicinet.com]

    Missing: Non-Hemolytic Unconjugated Hyperbilirubinemia
  • Fetal Erythroblastosis

    Risk Zone as a Predictor of Hyperbilirubinemia 39 TABLE 5.[pediatrics.aappublications.org] In a second case, delayed speech development was observed.[ncbi.nlm.nih.gov] Fetal and neonatal edition, 2018 May 25 [PubMed] Bilirubin Albumin Binding and Unbound Unconjugated Hyperbilirubinemia in Premature Infants., Amin SB,Wang H,, The Journal[knowledge.statpearls.com]

    Missing: Non-Hemolytic Unconjugated Hyperbilirubinemia

Similar symptoms