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18 Possible Causes for Hyperbilirubinemia, Onset in First Weeks or Months of Life, Pruritus

  • Cholestasis

    Clinical description The first cholestatic episode can occur at any age but onset within the first two decades of life is most common.[orpha.net] We believe our patient’s persistent direct hyperbilirubinemia with biopsy-confirmed cholestasis was also likely related to his AHC.[pediatrics.aappublications.org] Intractable pruritus of cholestasis leads to significant morbidity.[ncbi.nlm.nih.gov]

  • Intrahepatic Cholestasis

    Clinical description The first cholestatic episode can occur at any age but onset within the first two decades of life is most common.[orpha.net] Dubin-Johnson syndrome may manifest as conjugated hyperbilirubinemia, darkly pigmented liver, presence of abnormal pigment in the parenchyma of hepatocytes and abnormal distribution[ncbi.nlm.nih.gov] We present two cases of pregnancy after IVF treatment diagnosed with ICP following the development of OHSS, deteriorating liver function tests and severe pruritus.[ncbi.nlm.nih.gov]

  • Benign Recurrent Intrahepatic Cholestasis

    Clinical description The first cholestatic episode can occur at any age but onset within the first two decades of life is most common.[orpha.net] HYPERBILIRUBINEMIA 2.[slideshare.net] The course of serum parameters was accompanied by a dramatic clinical improvement of the patients symptoms (pruritus, jaundice, fatigue etc.).[ncbi.nlm.nih.gov]

  • 3Beta-Hydroxy-Delta5-C27-Steroid Oxidoreductase Deficiency

    The first cholestatic episode can occur at any age but onset within the first two decades of life is most common.[findzebra.com] The condition accounts for 1% to 2% of all occurrences of conjugated hyperbilirubinemia during infancy.[symptoma.com] In most cases, pruritus is absent. Liver function tests present elevated serum transaminases (AST, ALT), conjugated hyperbilirubinemia, and normal gamma-GT.[malacards.org]

  • Benign Recurrent Intrahepatic Cholestasis Type 1

    Clinical description The first cholestatic episode can occur at any age but onset within the first two decades of life is most common.[orpha.net] HYPERBILIRUBINEMIA 2.[slideshare.net] Pruritus is the chief complaint, predominantly affecting the hands and feet.[ijdvl.com]

  • Sepsis

    Early-onset sepsis is seen in the first week of life. Late onset sepsis occurs after 1 week through 3 months of age.[medlineplus.gov] Hyperbilirubinemia did not return in 3 months.[ncbi.nlm.nih.gov] […] likely to be related to polyclonal IVIG were allergic reactions ( Hentrich 2006 ; Werdan 2007 ); skin reactions such as erythema and exanthem ( Hentrich 2006 ; Werdan 2007 ); pruritus[doi.org]

  • Erythema Toxicum Neonatorum

    . [21] Onset is most likely in the first 6 months of life and approximately 25% of them present at or just after birth.[e-ijd.org] ISSUES OF PREGNANCY AND BIRTH FOR THE ADOLESCENT 6 QUESTIONS 17 ANSWERS 24 BIBLIOGRAPHY 27 13Hematol ogicOncologicImreunologic Disorders 30 RH INCOMPATIBILITY 32 NEONATAL HYPERBILIRUBINEMIA[books.google.de] Bronze baby syndrome Refers to diffuse gray-brown discoloration of the skin that can develop in infants 1-7 days after initiation of phototherapy for hyperbilirubinemia.[pedclerk.bsd.uchicago.edu]

  • Hepatoerythropoietic Porphyria

    […] of seizures in the first weeks or months of life.[mendelian.co] , red urine, dark diapers that show a red fluorescence under UV light Phototherapy for hyperbilirubinemia leads to severe skin blistering.[merckmanuals.com] It is characterised by a dark urine, marked cutaneous photosensitivity including blistering, burning and pruritus.[gpnotebook.co.uk]

  • Pneumatosis Vaginalis

    […] two years of life, peak incidence at 6 weeks of age Seasonal pattern - winter and early spring months Clinical Picture Symptoms • Sudden onset of respiratory difficulty •[flashcardmachine.com] Hypertrophic Cardiomyopathy, Hyperbilirubinemia, & Polycythemia 6.[cram.com] Enterobius vermicularis Female worms leave the rectum during the night and deposit eggs on the perianal skin, producing pruritus. 59. Tapeworm 60. Schistosomiasis 61.[slideshare.net]

  • Volvulus

    The onset occurred in the first week of life in 3 patients, at age 1.5 months in another, and at age 5 months in the last one, although the latter had previously visited the[analesdepediatria.org] Abdominal pain (RUQ, radiates epigastric), nausea, vomiting, fever, Murphy's sign Clinical (history & physical exam) Imaging (RUQ ultrasound) Labs ( leukocytosis, transamintis, hyperbilirubinemia[en.wikipedia.org] Onchocerciasis can cause pruritus, dermatitis, onchocercomata (subcutaneous nodules), and lymphadenopathies.[cdc.gov]

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