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1,996 Possible Causes for Hyperbilirubinemia, Onset in First Weeks or Months of Life, Scleral Icterus

  • Cholestasis

    Clinical description The first cholestatic episode can occur at any age but onset within the first two decades of life is most common.[orpha.net] We believe our patient’s persistent direct hyperbilirubinemia with biopsy-confirmed cholestasis was also likely related to his AHC.[pediatrics.aappublications.org] Her physical exam was remarkable for jaundice and scleral icterus without any stigmata of liver disease.[ncbi.nlm.nih.gov]

  • Cholestatic Jaundice

    […] jaundice [ jawn dis ] yellowness of skin, sclerae, mucous membranes, and excretions due to hyperbilirubinemia and deposition of bile pigments.[medical-dictionary.thefreedictionary.com] […] of urine and scleral icterus precede yellowing of skin Other causes of yellow skin carotenemia. carotenemia does not cause scleral icterus Hyperbilirubinemia per se has no[meddean.luc.edu] hyperbilirubinemia.[ptolemy.ca]

    Missing: Onset in First Weeks or Months of Life
  • Intrahepatic Cholestasis

    Clinical description The first cholestatic episode can occur at any age but onset within the first two decades of life is most common.[orpha.net] Dubin-Johnson syndrome may manifest as conjugated hyperbilirubinemia, darkly pigmented liver, presence of abnormal pigment in the parenchyma of hepatocytes and abnormal distribution[ncbi.nlm.nih.gov] Scleral icterus and jaundice were observed at 27 weeks.[ncbi.nlm.nih.gov]

  • Gilbert Syndrome

    Hyperbilirubinemia is an important clinical sign that often indicates severe hepatobiliary disease of different etiologies.[ncbi.nlm.nih.gov] Icterus Morphine Glucuronide These keywords were added by machine and not by the authors.[link.springer.com] Such combined defects can lead to severe hyperbilirubinemia and help to explain the finding of intermediate levels of hyperbilirubinemia in family members of patients with[emedicine.com]

    Missing: Onset in First Weeks or Months of Life
  • Autoimmune Hemolytic Anemia

    AIHAs can result in the classic set of symptoms associated with anemia (see page) as well as an unconjugated hyperbilirubinemia and in some cases jaundice if hemolysis is[pathwaymedicine.org] Examination demonstrated scleral icterus, splenomegaly, and anemia. By peripheral blood smear, the patient was diagnosed with Plasmodium ovale.[ncbi.nlm.nih.gov] […] findings are based on the severity of the patient's hemolysis and may include varying degrees of anemia, reticulocytosis, elevated lactate dehydrogenase (LDH), indirect hyperbilirubinemia[clinicaladvisor.com]

    Missing: Onset in First Weeks or Months of Life
  • Progressive Familial Intrahepatic Cholestasis

    Conjugated hyperbilirubinemia (total serum bilirubin 7.0 mg/dL, conjugated 5.0 mg/dL), high alkaline phosphatase (630 U/L; reference range for adults 35-150) normal serum[indianpediatrics.net] History The following may be noted in the history of a patient with progressive familial intrahepatic cholestasis (PFIC) Jaundice Scleral icterus Cutaneous jaundice Dark urine[emedicine.medscape.com] Ursodeoxycholic acid in the treatment of cholestasis and hyperbilirubinemia in pediatric intensive care unit patients. South Med J. 2002;95: 1276-79.[meddocsonline.org]

    Missing: Onset in First Weeks or Months of Life
  • Physiological Neonatal Jaundice

    Kaplan M, Hammerman C, Renbaum P et al (2000) Gibert’s syndrome and hyperbilirubinemia in ABO-incompatible neonates.[link.springer.com] The most notable signs of hyperbilirubinemia are jaundice and scleral icterus.[pathophys.org] Algorithm for the suggested evaluation of a term newborn with hyperbilirubinemia. Information from jaundice and hyperbilirubinemia in the newborn.[aafp.org]

    Missing: Onset in First Weeks or Months of Life
  • Pyruvate Kinase Deficiency

    We report an infant with neonatal hyperbilirubinemia due to pyruvate kinase deficiency.[ncbi.nlm.nih.gov] icterus (yellow coloring of the whites of the eyes) Abdominal pain Enlarged spleen (splenomegaly) Gallstones How is PK deficiency diagnosed?[agios.com] Subcommittee on Hyperbilirubinemia, American Academy of Pediatrics.[nature.com]

    Missing: Onset in First Weeks or Months of Life
  • Jaundice

    What Cancers Can Cause Hyperbilirubinemia?[jamanetwork.com] This is sometimes referred to as scleral icterus.[en.wikipedia.org] Treating any underlying cause of hyperbilirubinemia, such as infection While hyperbilirubinemia cannot be totally prevented, early recognition and treatment are important[chop.edu]

    Missing: Onset in First Weeks or Months of Life
  • Neonatal Hepatitis

    The levels of glutamic acid (Glu) in the BA group were significantly elevated compared to those in the NHS group, but still lower than the hyperbilirubinemia and normal controls[ncbi.nlm.nih.gov] At 30 hours of life, the infant was noted to have scleral icterus.[nature.com] Idiopathic neonatal hepatitis (INH) remains a diagnosis of exclusion in the neonate with conjugated hyperbilirubinemia.[ncbi.nlm.nih.gov]

    Missing: Onset in First Weeks or Months of Life

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