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2,048 Possible Causes for Hyperbilirubinemia, Onset in First Weeks or Months of Life, Secondary Biliary Cirrhosis

  • Cholestasis

    For quantification of secondary biliary cirrhosis, eosin staining was performed, which did not reveal any signs of liver remodeling, thus precluding the development of a chronic[ncbi.nlm.nih.gov] Clinical description The first cholestatic episode can occur at any age but onset within the first two decades of life is most common.[orpha.net] We believe our patient’s persistent direct hyperbilirubinemia with biopsy-confirmed cholestasis was also likely related to his AHC.[pediatrics.aappublications.org]

  • Cholelithiasis

    If obstruction is low-grade but prolonged, secondary biliary cirrhosis can result.[pathwaymedicine.org] All SCA patients are children (less than 16 years old) and were characterized by hyperbilirubinemia and 52 of them have cholelithiasis.[ncbi.nlm.nih.gov] Black stones contain polymerized calcium bilirubinate, most often secondary to cirrhosis or hemolysis; these almost always form within the gallbladder.[unboundmedicine.com]

    Missing: Onset in First Weeks or Months of Life
  • Intrahepatic Cholestasis

    […] due to inborn errors of metabolism 続発性胆汁性肝硬変 secondary biliary cirrhosis 日本住血吸虫症 schistosomiasis japonica 不明の慢性ウイルス性肝炎による肝硬変 cirrhosis due to chronic viral hepatitis, agent[jsge.or.jp] Dubin-Johnson syndrome may manifest as conjugated hyperbilirubinemia, darkly pigmented liver, presence of abnormal pigment in the parenchyma of hepatocytes and abnormal distribution[ncbi.nlm.nih.gov] Clinical description The first cholestatic episode can occur at any age but onset within the first two decades of life is most common.[orpha.net]

  • Cholestatic Jaundice

    Secondary Biliary Cirrhosis has a similar prognosis as cirrhosis from other causes, since once cirrhosis develops, it is largely irreversible.[myvmc.com] […] jaundice [ jawn dis ] yellowness of skin, sclerae, mucous membranes, and excretions due to hyperbilirubinemia and deposition of bile pigments.[medical-dictionary.thefreedictionary.com] Other causes of blockage within the ducts include malignancy, infection, and biliary cirrhosis. • External compression of the ducts may occur secondary to inflammation (eg[slideshare.net]

    Missing: Onset in First Weeks or Months of Life
  • Choledocholithiasis

    Secondary Biliary Cirrhosis has a similar prognosis as cirrhosis from other causes, since once cirrhosis develops, it is largely irreversible.[myvmc.com] This individual experienced hyperbilirubinemia that peaked at hospital presentation after she developed choledocholithiasis and secondary acute hepatitis.[ncbi.nlm.nih.gov] Other complications that may be seen are biliary stricture, intrahepatic biliary stones, and secondary biliary cirrhosis ( Table III ). Table III.[clinicaladvisor.com]

    Missing: Onset in First Weeks or Months of Life
  • Progressive Familial Intrahepatic Cholestasis

    PFIC3 evolves into secondary biliary cirrhosis. Gastrointestinal bleeding due to portal hypertension might be the presenting symptom in adolescents or young adults.[orpha.net] Conjugated hyperbilirubinemia (total serum bilirubin 7.0 mg/dL, conjugated 5.0 mg/dL), high alkaline phosphatase (630 U/L; reference range for adults 35-150) normal serum[indianpediatrics.net] […] due to inborn errors of metabolism 続発性胆汁性肝硬変 secondary biliary cirrhosis 日本住血吸虫症 schistosomiasis japonica 不明の慢性ウイルス性肝炎による肝硬変 cirrhosis due to chronic viral hepatitis, agent[jsge.or.jp]

    Missing: Onset in First Weeks or Months of Life
  • Primary Biliary Cirrhosis

    16 ICD-10-CM K74.5 Biliary cirrhosis, unspecified Approximate Synonyms Primary biliary cirrhosis Primary biliary cirrhosis, stage 4 Secondary biliary cirrhosis Clinical Information[icd9data.com] After two years, the risk of hyperbilirubinemia or clinical complications was approximately three times higher in the placebo group than in the ursodiol group.[nejm.org] Primary biliary cirrhosis differs from secondary biliary cirrhosis, in which the bile ducts are obstructed or damaged due to another cause such as a tumor.[columbiasurgery.org]

    Missing: Onset in First Weeks or Months of Life
  • Primary Sclerosing Cholangitis

    Stage 4 : end-stage disease with secondary biliary cirrhosis. Management Despite years of research, medical treatments are only at best able to help manage symptoms.[patient.info] The causes of hyperbilirubinemia after TIPS placement are very varied and it is crucial to perform a differential diagnosis to establish an early treatment.[ncbi.nlm.nih.gov] Fibrosis result in atrophy of biliary epithelial cells leading to cholestasis, fibrosis and secondary biliary cirrhosis.[symptoma.com]

    Missing: Onset in First Weeks or Months of Life
  • Biliary Tree Disease

    biliary cirrhosis and acute calculous cholecystitis. bacterial infection of the bile ducts. any lesion that creases bile flow obstruction (choledocholithiasis or stricture[quizlet.com] […] parenchymal transaminases (alanine aminotransferase, aspartate aminotransferase) and cholestatic enzymes (alkaline phosphatase and gamma glutamyl transferase) with or without hyperbilirubinemia[ncbi.nlm.nih.gov] Hyperbilirubinemia is associated with: Excessive red cell destruction (pre-hepatic). Hepatic disease. Post-hepatic obstruction (bile duct obstruction).[vetstream.com]

    Missing: Onset in First Weeks or Months of Life
  • Choledochal Cyst

    METHOD: We report a case of adult choledochal cyst with long-term complication of large stone cast and portal hypertension due to secondary biliary cirrhosis.[ncbi.nlm.nih.gov] Direct hyperbilirubinemia They were classified into 5 types by Todani in 1977.Classification was based on site of the cyst or dilatation. Type I to IV has been subtyped.[en.wikipedia.org] All patients had type IVa choledochal cysts, and the causes of PHT were secondary biliary cirrhosis (SBC) (two cases) and alcoholic liver disease (one case).[ncbi.nlm.nih.gov]

    Missing: Onset in First Weeks or Months of Life

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