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2,871 Possible Causes for Hypercalcemia

  • Stage IV Prostate Carcinoma

    Hypercalcemia is a potentially fatal condition in which the blood has very high levels of calcium.[] Zoledronic acid may be used to reduce the risk of complications from bone metastases or to treat cancer-related hypercalcemia. 13, 14 Denosumab (Xgeva ): Denosumab targets[] Associated symptoms of bone metastasis include pain, a higher risk of bone fracture and a condition known as hypercalcemia.[]

  • Non-Hodgkin Lymphoma

    Other features include anemia; hypercalcemia; and renal insufficiency. A malignant neoplasm of the bone marrow composed of plasma cells.[] Lymphoma Adult T-cell leukemia/lymphoma (ATL) is caused by infection with the retrovirus human T-lymphotrophic virus 1 and is frequently associated with lymphadenopathy, hypercalcemia[] A bone marrow-based plasma cell neoplasm characterized by a serum monoclonal protein and skeletal destruction with osteolytic lesions, pathological fractures, bone pain, hypercalcemia[]

  • Adenocarcinoma of the Breast

    Diffuse Worse during the late luteal phase of menstrual cycle Subsides with onset of menstruation Focal SOB/dyspnea Metastatic disease to the lungs Bone pain and symptoms of hypercalcemia[] About 10% of patients with bone metastases eventually develop hypercalcemia, which can also be treated with IV bisphosphonates.[]

  • Bone Metastasis

    Multivariate analysis revealed that 2 extra-bone metastatic organs, hypercalcemia, and pathologic fractures were independent poor prognostic factors (p 0.001, 0.001, and 0.033[] […] skills, knowledge of treatments including medication, surgery, and radiation therapy, and recognition of serious complications such as fracture, spinal cord compression, and hypercalcemia[] […] events caused by bone metastasis include aberrant bone remodeling (osteolytic, osteoblastic, and mixed), bone pain, fracture, spinal cord compression, and life-threatening hypercalcemia[]

  • Bronchogenic Carcinoma

    Hypercalcemia of malignancy is the most common cause of hypercalcemia in hospitalized patients.[] Humoral hypercalcemia, caused by tumor production of parathyroid-hormone-related protein, is the most common type of hypercalcemia of malignancy.[] For instance, Hypercalcemia is more common with squamous cell carcinoma due to ectopic secretion of the parathyroid hormone related peptide (PTHrP).[]

  • Paraneoplastic Syndrome

    […] is categorized according to the serum total calcium level 1 : mild hypercalcemia, 10.5 to 11.9 mg/dL; moderate hypercalcemia, 12 to 13.9 mg/dL; and severe hypercalcemia,[] To elucidate the pathogenesis of this humoral hypercalcemia, BRA and colony-stimulating activity in both the conditioned medium and cells were characterized.[] Among patients with only one PNS, hypertension (p 0.012) and hypercalcemia (p 0.000) were related to advanced stage.[]

  • Adenocarcinoma of the Prostate

    Virchows Arch. 2013 Apr;462(4):429-36. doi: 10.1007/s00428-013-1385-5. Epub 2013 Feb 27. Abstract Ductal adenocarcinoma (DAC) of the prostate is thought to have worse prognosis than prostatic acinar carcinoma (PAC). We aimed to evaluate the prognostic significance of histopathological patterns of DAC. A series of[…][]

  • Bronchioloalveolar Carcinoma

    It is the type most often associated with hypercalcemia. Non–small cell lung cancer. A cavitating right lower lobe squamous cell carcinoma.[]

  • Sarcoidosis

    […] leads to hypercalciuria and occasionally hypercalcemia.[] A 61-year-old man was diagnosed with sarcoidosis involving the lungs, eyes, parotid gland and extrathoracic lymph nodes complicated by chronic kidney injury and hypercalcemia[] The patient was started on aggressive intravenous fluid hydration and intravenous calcitonin, after which her altered mental status resolved and both kidney function and hypercalcemia[]

  • Graves Disease

    The possibility of their coexistence should therefore be taken into consideration in cases of hypercalcemia.[] In addition to osteoporosis, hyperthyroidism can cause blood calcium levels to rise ( hypercalcemia ) by as much as 25%.[] ., vitamin D intoxication with consequent hypercalcemia.[]

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