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525 Possible Causes for Hypercalcemia, Polyuria, Vomiting

  • Primary Hyperparathyroidism

    Hypercalcemia is found frequently in patients with cancer.[] A 46 year-old female patient presented to the hospital with ongoing and progressively increasing fatigue, severe nausea and vomiting, loss of appetite, constipation, palpitations[] Here, a 32 years old lady with burning to colicky recurrent upper abdominal pain, polyuria, polydipsia associated with anorexia, dyspepsia, generalized body ache, joint pain[]

  • Hypercalcemia

    hypercalcemia.[] She had nausea, vomiting, leg pain, polyuria, polydipsia, and muscle weakness. At the time of relapse, the ionized calcium level was 1.99 mmol/L.[] We present a case that presented with paresis, nausea, and vomiting. Malignant melanoma with spinal metastasis.[]

  • Pheochromocytoma

    Pheochromocytoma associated with hypercalcemia and ectopic secretion of calcitonin. Ann Intern Med . Aug 1979;91(2):208-10. [Medline] .[] […] hypertension; and a 6-month history of daily symptomatic hypertensive paroxysms, associated with chest pressure, unilateral flushing, dizziness, weakness, tachycardia, and polyuria[] The patient complained of vomiting and breathlessness. Computed tomography showed a shadow-like region with a similar appearance to interstitial pneumonia.[]

  • Hypercalcemia of Malignancy

    Abstract The etiology, pathophysiology, and diagnosis of hypercalcemia associated with malignant diseases are discussed.[] Those with moderate hypercalcemia (12 to 14 mg/d) can develop polydipsia, polyuria, clinical dehydration, muscle weakness, and changes in mental status.[] […] bone directly, hypercalcemia develops more rapidly and more aggressively than other causes of hypercalcemia, along with classic symptoms of dehydration, anorexia, nausea/vomiting[]

  • Vitamin D Toxicity

    Early surgery is suggested for otherwise asymptomatic, mildly hypercalcemia hyperparathyroidism that is accompanied by hypertension.[] These are the conditions that are followed by polydipsia and polyuria which are conditions of excessive thirst and urine experienced by the body.[] Clinical manifestations included nausea, vomiting, altered sensorium, constipation, pancreatitis, acute kidney injury and weight loss.[]

  • Metastatic Renal Cell Carcinoma

    The third patient developed grade 4 hypercalcemia due to RPD on day 3.[] This results in hypercalcemia, possibly associated with fatigue, polyuria, polydipsia, and exsiccosis, nausea and vomiting, cardiac arrhythmia,hypertension and altered sensorium[] Call your health care provider if you experience pain or swelling in the stomach area, vomiting blood, or black sticky stools.[]

  • Milk-Alkali Syndrome

    Milk-alkali syndrome is a rare cause of hypercalcemia characterized by the triad of hypercalcemia, renal insufficiency, and metabolic alkalosis that results from the overconsumption[] A 67-year-old woman was admitted to the hospital due to progressive mental changes, nausea and vomiting after a dose increase of an intrathecal morphine pump.[] Patients with a prolonged course of disease may experience muscle aches, tremor, polyuria, polydipsia, and pruritus.[]

  • Chronic Kidney Insufficiency

    Noncalcium-containing binders are preferred in patients with hypercalcemia, suspected adynamic bone disease, or evidence of vascular calcification on imaging.[] Further early indicators are polyuria, newly emerging or worsening hypertension or peripheral edemas. Depending on the etiology, there can also be flank pains or fever.[] Nausea, loss of appetite, and vomiting. Urea in the gastric juices may cause upset stomach. This can lead to malnutrition and weight loss.[]

  • Hyperparathyroidism

    However, to date, only two reports have described hyperparathyroidism and hypercalcemia in patients with SLC12A1 gene mutations.[] Immobilization (inability to move) and gastrointestinal illness with vomiting or diarrhea can cause calcium levels to rise.[] Polyuria can occur with renal failure. Cardiac arrhythmias can occur and even coma.[]

  • Metabolic Alkalosis

    Hypercalcemia and metabolic alkalosis were only partially corrected after rehydration, calcitonin and steroids.[] In most patients, the symptom of muscle weakness and polyuria occur early in life, which may be attributed to potassium depletion.[] Latent renal insufficiency and dehydration induced by protracted vomiting may easily induce a rapid and recurrent deterioration of renal function, and control of vomiting[]

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