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32 Possible Causes for Hypercalcemia, Splenic Metastasis, Wasting Syndrome

  • Bronchogenic Carcinoma

    Hypercalcemia of malignancy is the most common cause of hypercalcemia in hospitalized patients.[journals.lww.com] -Look for Homer's syndrome and wasting of the small muscles of the hand. · Patient 2 has signs of pleural effusion on one side. · Patient 3 shows signs of unilateral collapse[syrianclinic.com] […] them to easy rupture and causing hemoptysis Dyspnea (25%) Extrinsic or intraluminal airway obstruction Activation of mechanoreceptors and chemoreceptors in lungs due to cachexia[epomedicine.com]

  • Adenocarcinoma of the Prostate

    Weight loss, cachexia. Signs Advanced disease: general malaise, bone pain, anorexia, weight loss, obstructive nephropathy, paralysis due to cord compression.[patient.info] Findings in patients with advanced disease may include the following: Cancer cachexia Bony tenderness Lower-extremity lymphedema or deep venous thrombosis Adenopathy Overdistended[emedicine.medscape.com]

  • Renal Cell Carcinoma

    Google Scholar 7 : A parathyroid hormone-related protein implicated in malignant hypercalcemia: cloning and expression. Science 1987 ; 237 : 893.[doi.org] There have not been any cases of splenic inflammatory pseudotumors presenting or evolving with metastasis.[scielo.br] Cachexia, defined as the presence of at least 1 of these findings, was noted in 35.3% of patients.[ncbi.nlm.nih.gov]

  • Carcinoma of the Prostate

    We present a case of small cell prostate carcinoma with hypercalcemia in a 75-year-old man. He was diagnosed as having stage T3bN1M0 adenocarcinoma of the prostate.[ncbi.nlm.nih.gov] Splenic metastasis. Prostate carcinomas usually occur after the age of 50, with a higher incidence after the age of 70 1.[scielo.br] Clinical examination should be thoroughly performed and may reveal cachexia, adenopathy, or an overdistended bladder.[symptoma.com]

  • Skin Cancer

    It often has a paraneoplastic syndrome causing ectopic production of parathyroid hormone-related protein, resulting in hypercalcemia, but paraneoplastic syndrome is more commonly[en.wikipedia.org] BACKGROUND: To investigate the association of DNA nucleotide excision repair (NER) defects with neurological degeneration, cachexia and cancer, we performed autopsies on 4[ncbi.nlm.nih.gov] The clinical spectrum encompassed severe cachexia in the XP-A (XP12BE) patient, numerous skin cancers in the XP-A and two XP-C (XP24BE and XP1BE) patients and only few skin[ncbi.nlm.nih.gov]

  • Islet Cell Tumor

    […] await a clearer delineation of the cause of the hypercalcemia.[ncbi.nlm.nih.gov] […] tumors, Castleman disease, gastrointestinal stromal tumor, splenic artery aneurysm and accessory spleen were selected in this pictorial review for differential diagnosis[ncbi.nlm.nih.gov] […] that spread serpiginously and then reveal central points of healing. [44] Hyperglucagonemia in patients with glucagonomas results in glucose intolerance (ie, diabetes) and cachexia[emedicine.medscape.com]

  • Adenocarcinoma of the Ovary

    Hypercalcemia in association with mucinous adenocarcinoma of the ovary has not previously been reported. Such a case is presented.[ncbi.nlm.nih.gov] […] parenchymal metastasis and/or metastases to extra-abdominal organs (including inguinal lymph nodes and lymph nodes outside the abdominal cavity) and/or transmural involvement[merckmanuals.com] In advanced stages, the size and growth of the tumor can lead to: Abdominal pain and ascites Cancer cachexia Possible disruption of menstrual cycle Dyspnea due to malignant[amboss.com]

  • Glucagonoma

    Hypercalcemia occurred when the patient underwent octreotide acetate long-acting release.[ncbi.nlm.nih.gov] Our current case underwent lymph node dissection, during which eight splenic hilar lymph nodes were detected and three were found to be with tumor metastasis.[tgh.amegroups.com] Tabs Content Clinical Overview Diagnosis Indications for Testing Pancreatic tumor Clinical symptoms of glucose intolerance, hyperglycemia, weight loss and cachexia, and migratory[arupconsult.com]

  • Metastatic Ovarian Carcinoma

    It often is associated with hypercalcemia. The most common form of sarcoma in the ovary is the mixed mesodermal sarcoma or carcinosarcoma.[emedicine.medscape.com] Splenic metastasis primarily occurred years after surgery. Splenic metastasis was only detected in four cases when ovarian cancer was first diagnosed.[spandidos-publications.com] CASE REPORT In April 2015, a 59-year old woman was referred to the Oncological Department after onset of dyspnea, tachycardia, polypnea and cachexia.[jpmsonline.com]

  • Leukoerythroblastic Anemia

    However, pain and tenderness of affected bones, pathologic fractures, and hypercalcemia causing nausea, symptoms of anemia, muscle weakness, or stupor may bring patients to[medtextfree.wordpress.com] Synchronous bone marrow metastasis from primary splenic angiosarcoma. Am Surg 2010;76:160-162. Wang C, Rabah R, Blackstein M, Riddell RH.[revistas.unc.edu.ar] […] metabolic function of cancer patients, as sponses include host anti-tumor immune reactivity, tumor well as the production of hormones by tumors is also review dormancy, cachexia[books.google.com]

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