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576 Possible Causes for Hypercalcemia, Splenomegaly

  • Adult T-Cell Leukemia - Lymphoma

    Organomegaly, cutaneous conditions, and hypercalcemia represent the main characteristics of the disease.[ncbi.nlm.nih.gov] Splenomegaly was also observed.[ncbi.nlm.nih.gov] Physical examination and imaging studies show massive splenomegaly with no lymphadenopathy. There was no hypercalcemia or increased in serum LDH.[pathologyoutlines.com]

  • Hypervitaminosis A

    Hypervitaminosis A has been associated with hypercalcemia.[ncbi.nlm.nih.gov] Further systemic consequences of HA are hepatotoxicity, hepatomegaly, splenomegaly, ascites, migratory arthritis, and hepatic hydrothorax.[symptoma.com] Splenomegaly. Raised intracranial pressure. Stupor. Limited body movement. Cirrhosis of liver.[nhp.gov.in]

  • Sarcoidosis

    […] leads to hypercalciuria and occasionally hypercalcemia.[doi.org] Abdomen Check for hepatomegaly and splenomegaly.[patient.info] Hypercalciuria with or without hypercalcemia is a well-known complication of sarcoidosis, the pathogenesis of which is not fully understood.[ncbi.nlm.nih.gov]

  • Non-Hodgkin Lymphoma

    Other features include anemia; hypercalcemia; and renal insufficiency. A malignant neoplasm of the bone marrow composed of plasma cells.[icd9data.com] Splenomegaly. Hepatomegaly. Intermediate- and high-grade lymphomas: Most patients present with rapidly growing and bulky lymphadenopathy.[patient.info] Lymphoma Adult T-cell leukemia/lymphoma (ATL) is caused by infection with the retrovirus human T-lymphotrophic virus 1 and is frequently associated with lymphadenopathy, hypercalcemia[web.archive.org]

  • Hodgkin's Disease

    This increase in blood calcium, or hypercalcemia, causes subtle signs that are important for both Hodgkin's survivors and their families to recognize.[livestrong.com] The presenting feature common in all cases was superficial lymphadenopathy followed by hepatomegaly in 17 (20%) cases and splenomegaly in 16 (19%).[ncbi.nlm.nih.gov] Hodgkin's lymphoma symptoms include night sweats, enlarged lymph nodes, splenomegaly, and back pain. Treatment entails radiotherapy or chemotherapy.[medscape.org]

  • Pulmonary Tuberculosis

    USG abdomen showed a liver of normal size and echo pattern with intrahepatic biliary radicle dilatation (IHBRD) in the left lobe, splenomegaly (18 cm), normal common bile[termedia.pl] Physical findings are also variable and in descending order of frequency are: fever, wasting, hepatomegaly, pulmonary findings, lymphadenopathy, splenomegaly.[southsudanmedicaljournal.com]

  • B-Precursor Acute Lymphoblastic Leukemia

    64.0%) 66 (66%) 62 (%) 0.556 Bleeding 96 (48.0%) 45 (45%) 51 (51%) 0.396 Lymphadenopathy 112 (56.0%) 53 (53%) 59 (59%) 0.393 Hepatomegaly 84 (42.0%) 46 (46%) 38 (38%) 0.252 Splenomegaly[omicsonline.org] […] even trigger hemophagocytic lymphohistiocytosis and macrophage activation syndrome, which are disorders of abnormal immune system activation characterized by high fever, splenomegaly[dovepress.com]

  • Multidrug-resistant Tuberculosis

    On January 9, 1986, a 30-year-old black man (patient 8 in Tables 1-3) presented to a hospital emergency room with an illness of 2 months' duration. The illness was characterized by cough, weakness, malaise, fever, night sweats, shortness of breath, and hemoptysis. The patient's chest radiograph showed extensive[…][cdc.gov]

  • Hepatic Sarcoidosis

    We report a case of early recurrence of sarcoidosis in the liver allograft diagnosed on biopsy in a patient who presented with severe hypercalcemia, kidney dysfunction, and[ncbi.nlm.nih.gov] In addition there was fever, itching, splenomegaly and abdominal lymphadenopathy in some. CT scan revealed mediastinal lymphadenopathy in all.[ncbi.nlm.nih.gov] However a moderately increased Serum Angiotensin Converting Enzyme and hypercalcemia were present.[minervamedica.it]

  • Plasma Cell Leukemia

    Patient also had azotemia, hypercalcemia, and hyperuricemia. The patient was started on chemotherapy along with supportive care.[ncbi.nlm.nih.gov] Enlarged lymph nodes in axillary, pectoral, paratracheal, and periportal regions as well as slight hepatomegaly and splenomegaly were confirmed.[ncbi.nlm.nih.gov] Compared with multiple myeloma, pPCL presents more often with extramedullary involvement, anemia, thrombocytopenia, hypercalcemia, elevated serum β(2)-microglobulin and lactate[ncbi.nlm.nih.gov]

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