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319 Possible Causes for Hypercellular Bone Marrow

  • Paroxysmal Nocturnal Hemoglobinuria

    Bone marrow failure is present in all patients with PNH, even when peripheral blood counts are normal and the bone marrow is hypercellular.[] Concerned with the apparent intravascular hemolysis, a bone marrow biopsy showed hypercellularity and normal cytogenetics.[] marrow biopsy Indicated when pancytopenia is present to rule out other disorders or when marrow transplantation considered Reveals normal to hypercellular marrow with erythroid[]

  • Myeloproliferative Disease

    Image shows: PV bone marrow (hypercellular) Picture of normal bone marrow for comparison Myeloproliferative Disorders: -Polycythemia Vera (PV) * Peripheral blood findings[] Bone marrow histology shows hypercellularity in most of these disorders. In the case of myelofibrosis, bone marrow fibrosis is demonstrated on the reticulin stain.[] . 10 Initially, the bone marrow is hypercellular, but normal hematopoiesis is diminished as the bone marrow becomes fibrotic and patients become pancytopenic ( Figure 2 ).[]

  • Polycythemia Vera

    Bone marrow biopsy showing hypercellularity for age with trilineage growth (panmyelosis) including prominent erythroid, granulocytic and megakaryocytic proliferation with[] Important manifestations of these disorders are bone marrow hypercellularity and pan-myeloid myeloproliferation, leading to overproduction of one or more hematopoietic lineages[] Bone marrow film at 100X magnification demonstrating hypercellularity and increased number of megakaryocytes. Courtesy of U.[]

  • Chronic Phase of Chronic Myeloid Leukemia

    […] t(9;22) present Mature neutrophils show prominent hyposegmentation Accelerated phase - bone marrow biopsy: Moderately hypercellular bone marrow biopsy with numerous megakaryocytes[] A bone marrow biopsy and aspiration demonstrated a hypercellular marrow with no other significant morphologic abnormalities.[] Bone Marrow The bone marrow is hypercellular, with cellularity of 75% to 90% and very little fat.[]

  • Secondary Polycythemia

    The renal biopsy revealed membranous nephropathy, and the bone marrow biopsy disclosed hypercellular marrow with mild panhyperplasia.[] Bone marrow and aspirate: Tend to be hypercellular in PV.[] The bone marrow was hypercellular and showed proliferation of all three cell lines. Arterial blood gas analysis showed pO 2 93.6 mmHg and oxygen saturation of 97%.[]

  • Acute Leukemia

    The bone marrow was hypercellular, with 64% blasts, which were large in size and showed low nucleus: cytoplasm ratio, monocytoid features, and blue-gray cytoplasm; 80% of[]

  • Chronic Myeloid Leukemia

    marrow Early myeloid cells (eg, myeloblasts, myelocytes, metamyelocytes, nucleated red blood cells) Bone marrow findings Ph chromosome (a reciprocal translocation of chromosomal[] […] material between chromosomes 9 and 22) BCR/ABL mutation Hypercellularity, with expansion of the myeloid cell line (eg, neutrophils, eosinophils, basophils) and its progenitor[] Platelet counts low, normal, or increased Leukocyte alkaline phosphatase stains very low to absent in most cells Leukoerythroblastosis, with circulating immature cells from the bone[]

  • Congenital Hemolytic Anemia

    From Wikipedia, the free encyclopedia Jump to: navigation , search Congenital hemolytic anemia Classification and external resources Specialty hematology ICD - 10 D55 - D58 ICD - 9-CM 282 MeSH D000745 [ edit on Wikidata ] Congenital hemolytic anemia (or hereditary hemolytic anemia ) refers to hemolytic anemia which is[…][]

  • Amegakaryocytic Thrombocytopenia

    […] by normal-to-hypercellular bone marrow.[] […] megakaryocytes in an otherwise normal bone marrow. [1] It needs to be differentiated from the more common disorder, immune thrombocytopenic purpura (ITP), which is characterized[] Acquired amegakaryocytic thrombocytopenic purpura (AATP) is an uncommon hematological disorder, characterized by severe thrombocytopenia and significantly decreased to absent marrow[]

  • Dihydrofolate Reductase Deficiency

    marrow biopsy and aspirate may show a hypercellular bone marrow with a megaloblastic maturation of cells, which morphologically resembles changes of vitamin B12 deficiency[] […] out cobalamin (Vitamin B12) deficiency because folate treatment will not improve neurologic abnormalities due to cobalamin deficiency Microscopic (histologic) description Bone[]

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