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153 Possible Causes for Hypercellular Bone Marrow, Lactate Dehydrogenase Increased

  • Hereditary Spherocytosis

    Reticulocytosis, increased bilirubin, increased lactate dehydrogenase, increased urinary and fecal urobilinogen, and decreased haptoglobin, reflect increased erythrocyte production[clinicaladvisor.com] Other biochemical changes of hemolysis also are also present, including: increased lactate dehydrogenase (LDH) increased unconjugated bilirubin decreased serum haptoglobin[steadyhealth.com] Lactate dehydrogenase Levels are increased Total and unconjugated bilirubin Levels are increased Bone marrow Aspiration Examination It shows hyperplasia of the erythroid cells[medcaretips.com]

  • Paroxysmal Nocturnal Hemoglobinuria

    The effect of eculizumab on intravascular hemolysis was demonstrated by a reduction in lactate dehydrogenase levels at all measurements after baseline.[ncbi.nlm.nih.gov] These patients tend to have a normocellular to hypercellular bone marrow with erythroid hyperplasia, an elevated reticulocyte count, a large population of PNH cells (usually[bloodjournal.hematologylibrary.org] […] in lactate dehydrogenase levels.[nejm.org]

  • Leukemia

    Bone marrow aspirate showed hypercellularity with increased myelopoiesis and markedly suppressed megakaryopoiesis giving an impression of acute myeloid leukemia and was confirmed[ncbi.nlm.nih.gov] Another important feature of bone marrow samples is its cellularity. Normal bone marrow contains hematopoietic (blood-forming) cells and fat cells.[web.archive.org] Marrow with too many blood-forming cells is said to be hypercellular. If too few of these cells are found, the marrow is called hypocellular.[web.archive.org]

  • Chronic Myeloid Leukemia

    […] serum lactate dehydrogenase level, anemia, and palpable splenomegaly.[doi.org] marrow biopsy: Moderately hypercellular bone marrow biopsy with numerous megakaryocytes Increased reticulin fibers (reticulin stain) Marked hypercellularity Myeloblastic[pathologyoutlines.com] […] numbers of eosinophils and basophils Differential WCC shows granulocytes at all stages of development Anaemia (normocytic/normochromic) Biochemistry: Lactate dehydrogenase[geekymedics.com]

  • Autoimmune Hemolytic Anemia

    Unconjugated bilirubin is usually, but not always, elevated and urine urobilinogen is increased. Lactate dehydrogenase is usually elevated into the thousands.[clinlabnavigator.com] Subsequently, the patient underwent a bone marrow biopsy that showed a hypercellular marrow with erythroid hyperplasia, but no evidence of dysplasia or lymphoma.[jmedicalcasereports.com] Increased serum unconjugated bilirubin, increased lactate dehydrogenase (LDH) and reduced or absent haptoglobin. Increased urinary urobilinogen, haemosiderinuria.[patient.info]

  • Pernicious Anemia

    An elderly black man was admitted to our institution with macrocytic anemia, dysphagia, and significant weight loss. Results of an esophagogram were suggestive of achalasia. Gastric adenocarcinoma infiltrating the gastric cardia was seen on gastroscopy. The mode of presentation of gastric cancer in this case has[…][ncbi.nlm.nih.gov]

  • Cooley's Anemia

    […] and a decreasing trend in the serum lactate dehydrogenase (LDH) and serum unconjugated bilirubin levels.[onlinelibrary.wiley.com] Hydroxyurea therapy is associated with an improvement in the ineffective erythropoiesis, as reflected by an increase in the Hb level, a reduction in red cell transfusion requirement[onlinelibrary.wiley.com]

  • Chronic Phase of Chronic Myeloid Leukemia

    marrow biopsy: Moderately hypercellular bone marrow biopsy with numerous megakaryocytes Increased reticulin fibers (reticulin stain) Marked hypercellularity Myeloblastic[pathologyoutlines.com] A bone marrow biopsy and aspiration demonstrated a hypercellular marrow with no other significant morphologic abnormalities.[hematologyandoncology.net] marrow Early myeloid cells (eg, myeloblasts, myelocytes, metamyelocytes, nucleated red blood cells) Bone marrow findings Ph chromosome (a reciprocal translocation of chromosomal[emedicine.medscape.com]

  • Acute Leukemia

    ALL : Hypercellular bone marrow Numerous tightly packed lymphoblasts with undetectable cytoplasm, round, irregular, cleaved nuclei, dispersed chromatin, small nucleoli B[pathologyoutlines.com] Bone marrow aspirate examination revealed hypercellularity with 70% blast cells.[ncbi.nlm.nih.gov] Bone marrow aspiration demonstrated hypercellular marrow (nucleated cell count 1.84 104/μL) and 89.0% of blast-like cells of all nucleated cells.[ncbi.nlm.nih.gov]

  • Microangiopathic Hemolytic Anemia

    Laboratory abnormalities Anemia Increased lactate dehydrogenase. Increased indirect bilirubin. Decreased haptoglobin. Increased urine urobilinogen.[clinicaladvisor.com] Characteristic laboratory data are a negative direct antiglobulin (Coombs) test, an increased lactate dehydrogenase (LDH) level, increased indirect bilirubin, and low haptoglobin[springerplus.springeropen.com] Increased serum unconjugated bilirubin, increased lactate dehydrogenase (LDH) and reduced or absent haptoglobin. Increased urinary urobilinogen, haemosiderinuria.[patient.info]

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