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301 Possible Causes for Hypercellular Bone Marrow, Leukemia

  • Myeloproliferative Disease

    There are two big categories of leukemias: acute leukemias and chronic leukemias.[pathologystudent.com] Image shows: PV bone marrow (hypercellular) Picture of normal bone marrow for comparison Myeloproliferative Disorders: -Polycythemia Vera (PV) * Peripheral blood findings[quizlet.com] Bone marrow histology shows hypercellularity in most of these disorders. In the case of myelofibrosis, bone marrow fibrosis is demonstrated on the reticulin stain.[emedicine.com]

  • Polycythemia Vera

    CONCLUSIONS: To date, this case is the first description of a Breakpoint cluster region-Abelson murine leukemia viral oncogene homolog 1-positive chronic myeloid leukemia,[ncbi.nlm.nih.gov] bone marrow 5.[slideshare.net] Based on the presence of severe hypercellularity of the bone marrow and positivity for the JAK2V617F mutation, we finally diagnosed the patient with PV.[ncbi.nlm.nih.gov]

  • Chronic Phase of Chronic Myeloid Leukemia

    Chronic myelogenous leukemia (CML) is a myeloproliferative disease also referred to as chronic myeloid leukemia.[symptoma.com] marrow biopsy: Moderately hypercellular bone marrow biopsy with numerous megakaryocytes Increased reticulin fibers (reticulin stain) Marked hypercellularity Myeloblastic[pathologyoutlines.com] , Myeloid, Chronic-Phase/diagnosis Leukemia, Myeloid, Chronic-Phase/drug therapy* Leukemia, Myeloid, Chronic-Phase/genetics Male Middle Aged Patched-1 Receptor/physiology*[ncbi.nlm.nih.gov]

  • Chronic Myeloid Leukemia

    What You Should Know Chronic myeloid leukemia (CML) is also called chronic myelogenous leukemia, chronic granulocytic leukemia and chronic myelocytic leukemia.[lls.org] marrow biopsy: Moderately hypercellular bone marrow biopsy with numerous megakaryocytes Increased reticulin fibers (reticulin stain) Marked hypercellularity Myeloblastic[pathologyoutlines.com] Chronic myeloid leukemia (CML), also known as chronic myelogenous leukemia, is the most common myeloproliferative disorder.[symptoma.com]

  • Leukemia

    There are basically 4 types of leukemia, namely: Acute lymphocytic leukemia, acute myelogenous leukemia, chronic lymphocytic leukemia and chronic myeloid leukemia.[symptoma.com] Another important feature of bone marrow samples is its cellularity. Normal bone marrow contains hematopoietic (blood-forming) cells and fat cells.[web.archive.org] […] with many segmented cells more than half of the bone marrow volume.[web.archive.org]

  • Paroxysmal Nocturnal Hemoglobinuria

    It may be associated with aplastic anemia , myelodysplastic syndrome, or acute myelogenous leukemia . Risk factors, except for prior aplastic anemia, are not known.[nlm.nih.gov] These patients tend to have a normocellular to hypercellular bone marrow with erythroid hyperplasia, an elevated reticulocyte count, a large population of PNH cells (usually[bloodjournal.hematologylibrary.org] […] chromosomal abnormalities involving chromosome bands 13q12 to 13q14 (13q12q14) are frequently found in various hematologic malignancies, including chronic lymphoblastic leukemia[ncbi.nlm.nih.gov]

  • Acute Leukemia

    […] include: Acute myeloid leukemia Acute erythroid leukemia Acute lymphoblastic leukemia T-cell acute lymphoblastic leukemia Adult T-cell leukemia/lymphoma (Precursor)T-lymphoblastic[en.wikipedia.org] ALL : Hypercellular bone marrow Numerous tightly packed lymphoblasts with undetectable cytoplasm, round, irregular, cleaved nuclei, dispersed chromatin, small nucleoli B[pathologyoutlines.com] Bone marrow aspirate examination revealed hypercellularity with 70% blast cells.[ncbi.nlm.nih.gov]

  • Autoimmune Hemolytic Anemia

    Abstract Ibrutinib (IBR) covalently binds to the active site of Bruton's tyrosine kinase (BTK) and is used for the treatment of relapsed/refractory chronic lymphocytic leukemia[ncbi.nlm.nih.gov] Subsequently, the patient underwent a bone marrow biopsy that showed a hypercellular marrow with erythroid hyperplasia, but no evidence of dysplasia or lymphoma.[doi.org] Abstract Infectious complications are a major cause of morbidity and mortality in patients with chronic lymphocytic leukemia (CLL) due to impaired immunity secondary to the[ncbi.nlm.nih.gov]

  • Chronic Neutrophilic Leukemia

    We report the first case of CNL with an associated leukemia cutis.[ncbi.nlm.nih.gov] bone marrow with predominant neutrophilic granulopoiesis (M:E is 20:1 or more), the number of myeloblasts and promyelocytes is not increased, myelocytes and mature neutrophils[atlases.muni.cz] These cases are characterized by a high number of mature neutrophils in peripheral blood (PB), a hypercellular bone marrow due to neutrophilic granulocyte proliferation and[learningcenter.ehaweb.org]

  • Secondary Polycythemia

    We report an 18-year-old female with isolated renal relapse of acute lymphoblastic leukemia accompanied by polycythemia.[ncbi.nlm.nih.gov] The renal biopsy revealed membranous nephropathy, and the bone marrow biopsy disclosed hypercellular marrow with mild panhyperplasia.[ncbi.nlm.nih.gov] Leukemia kidney infiltration can cause secondary polycythemia by activating hypoxia-inducible factor (HIF) pathway . European Journal of Pediatrics , 172 (6), 829-832.[keio.pure.elsevier.com]

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