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264 Possible Causes for Hypercellular Bone Marrow, Leukocytosis

  • Myeloproliferative Disease

    The chronic myeloproliferative diseases are characterized by relatively effective hematopoiesis, which results in a hypercellular bone marrow and elevation of one or more[clinlabnavigator.com] Leukocytosis is also found in patients with essential thrombocythemia (primary thrombocythemia).[medindia.net] Bone marrow histology shows hypercellularity in most of these disorders. In the case of myelofibrosis, bone marrow fibrosis is demonstrated on the reticulin stain.[emedicine.com]

  • Leukemia

    Bone marrow aspirate showed hypercellularity with increased myelopoiesis and markedly suppressed megakaryopoiesis giving an impression of acute myeloid leukemia and was confirmed[ncbi.nlm.nih.gov] Evaluation Step 0: Leukocytosis ( White Blood Cell Count 11,000/mm3) Confirmed with a second Complete Blood Count with differential No other obvious cause for Leukocytosis[fpnotebook.com] Another important feature of bone marrow samples is its cellularity. Normal bone marrow contains hematopoietic (blood-forming) cells and fat cells.[web.archive.org]

  • Polycythemia Vera

    bone marrow 5.[slideshare.net] […] the leukocytosis.[onclive.com] Based on the presence of severe hypercellularity of the bone marrow and positivity for the JAK2V617F mutation, we finally diagnosed the patient with PV.[ncbi.nlm.nih.gov]

  • Chronic Myeloid Leukemia

    marrow biopsy: Moderately hypercellular bone marrow biopsy with numerous megakaryocytes Increased reticulin fibers (reticulin stain) Marked hypercellularity Myeloblastic[pathologyoutlines.com] Her disease was managed during pregnancy using interferon-α alone despite persistent leukocytosis.[ncbi.nlm.nih.gov] One month later, he presented with progressive leukocytosis (mostly neutrophilia) and splenomegaly.[ncbi.nlm.nih.gov]

  • Chronic Phase of Chronic Myeloid Leukemia

    marrow biopsy: Moderately hypercellular bone marrow biopsy with numerous megakaryocytes Increased reticulin fibers (reticulin stain) Marked hypercellularity Myeloblastic[pathologyoutlines.com] CP-CML patients are generally asymptomatic and diagnosis of the disease is based on the incidental detection of hematological alterations: While leukocytosis 50*10 9/l is[symptoma.com] […] and hypercellular marrow Peripheral blood leukocytosis Granulocytes at all stages of maturation Two peaks: segmented neutrophils and myelocytes Basophilia Eosinophilia (frequent[surgpathcriteria.stanford.edu]

  • Hereditary Spherocytosis

    Reticulocytosis of 15 to 30% and leukocytosis are common.[merckmanuals.com] It also results in leukocytosis and thrombocytosis. On peripheral blood smear, spherocytes are unchanged or may even increase.[medcaretips.com]

  • Autoimmune Hemolytic Anemia

    Subsequently, the patient underwent a bone marrow biopsy that showed a hypercellular marrow with erythroid hyperplasia, but no evidence of dysplasia or lymphoma.[jmedicalcasereports.com] Mild leukocytosis and thrombocytosis may be present.[clinlabnavigator.com] There was no fever, leukocytosis, or pertinent travel history to suggest malaria or babesiosis, and there was no evidence of spider or insect bites.[casesjournal.biomedcentral.com]

  • Secondary Polycythemia

    The renal biopsy revealed membranous nephropathy, and the bone marrow biopsy disclosed hypercellular marrow with mild panhyperplasia.[ncbi.nlm.nih.gov] Factors like older age, leukocytosis and thrombosis have been shown to increase the risk of mortality.[bloodjournal.org] Bone marrow is hypercellular with prominent megakaryocytes. Serum erythropoietin level is usually low. Blood viscosity is increased.[labpedia.net]

  • Acute Leukemia

    ALL : Hypercellular bone marrow Numerous tightly packed lymphoblasts with undetectable cytoplasm, round, irregular, cleaved nuclei, dispersed chromatin, small nucleoli B[pathologyoutlines.com] A 43-year-old female presented with leukocytosis and bicytopenia.[ncbi.nlm.nih.gov] Dysplasia is an abnormal development of immature cells in the presence of leukocytosis (increased WBC count).[healthline.com]

  • Chronic Neutrophilic Leukemia

    bone marrow with predominant neutrophilic granulopoiesis (M:E is 20:1 or more), the number of myeloblasts and promyelocytes is not increased, myelocytes and mature neutrophils[atlases.muni.cz] Differential diagnostic challenge of chronic neutrophilic leukemia in a patient with prolonged leukocytosis , Journal of Hematopathology, 2008, 23-27, DOI: 10.1007/s12308-[paperity.org] DIAGNOSIS: Key diagnostic criteria include leukocytosis of 25 10(9) /l (of which 80% are neutrophils) with 2014 Wiley Periodicals, Inc.[ncbi.nlm.nih.gov]

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