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241 Possible Causes for Hypercellular Bone Marrow, Leukocytosis

  • Chronic Myeloid Leukemia

    marrow biopsy: Moderately hypercellular bone marrow biopsy with numerous megakaryocytes Increased reticulin fibers (reticulin stain) Marked hypercellularity Myeloblastic[pathologyoutlines.com] Her disease was managed during pregnancy using interferon-α alone despite persistent leukocytosis.[ncbi.nlm.nih.gov] One month later, he presented with progressive leukocytosis (mostly neutrophilia) and splenomegaly.[ncbi.nlm.nih.gov]

  • Polycythemia Vera

    bone marrow 5.[slideshare.net] During multivariable analysis, leukocytosis 15 109/l, palpable splenomegaly and grade 1 BM reticulin fibrosis remained significant.[ncbi.nlm.nih.gov] Based on the presence of severe hypercellularity of the bone marrow and positivity for the JAK2V617F mutation, we finally diagnosed the patient with PV.[ncbi.nlm.nih.gov]

  • Myeloproliferative Disease

    The chronic myeloproliferative diseases are characterized by relatively effective hematopoiesis, which results in a hypercellular bone marrow and elevation of one or more[clinlabnavigator.com] […] a Philadelphia (Ph) chromosome without DNA breakpoints in the M-bcr region; (3) the spontaneous loss of detectable Ph-positive cells, 5 years after the first finding of leukocytosis[ncbi.nlm.nih.gov] Leukocytosis is also found in patients with essential thrombocythemia (primary thrombocythemia).[medindia.net]

  • Chronic Phase of Chronic Myeloid Leukemia

    marrow biopsy: Moderately hypercellular bone marrow biopsy with numerous megakaryocytes Increased reticulin fibers (reticulin stain) Marked hypercellularity Myeloblastic[pathologyoutlines.com] CP-CML patients are generally asymptomatic and diagnosis of the disease is based on the incidental detection of hematological alterations: While leukocytosis 50*10 9/l is[symptoma.com] […] and hypercellular marrow Peripheral blood leukocytosis Granulocytes at all stages of maturation Two peaks: segmented neutrophils and myelocytes Basophilia Eosinophilia (frequent[surgpathcriteria.stanford.edu]

  • Acute Leukemia

    ALL : Hypercellular bone marrow Numerous tightly packed lymphoblasts with undetectable cytoplasm, round, irregular, cleaved nuclei, dispersed chromatin, small nucleoli B[pathologyoutlines.com] A 43-year-old female presented with leukocytosis and bicytopenia.[ncbi.nlm.nih.gov] Dysplasia is an abnormal development of immature cells in the presence of leukocytosis (increased WBC count).[healthline.com]

  • Hairy Cell Leukemia

    Fig. 2: TRAP ; Fig. 3: hypercellular bone marrow with monotonous "fried egg" lymphocytes with abundant cytoplasm Cytology description Small / intermediate size cells with[pathologyoutlines.com] The 3 HCL-v patients had leukocytosis and received chemotherapy with variable outcome.[ncbi.nlm.nih.gov] Bone marrow aspiration showed hypercellular marrow with cells characterized by irregular windblown-appearing cell borders with pseudopod-like projections.[ncbi.nlm.nih.gov]

  • Leukemia

    Evaluation Step 0: Leukocytosis ( White Blood Cell Count 11,000/mm3) Confirmed with a second Complete Blood Count with differential No other obvious cause for Leukocytosis[fpnotebook.com] They usually manifest as abnormal leukocytosis with or without cytopenia in an otherwise asymptomatic person.[merckmanuals.com] A complete blood count usually reveals leukocytosis and other abnormally elevated or depressed cell lines.[aafp.org]

  • Cryptogenic Organizing Pneumonia

    Sweet's syndrome or acute febrile neutrophilic dermatosis is characterized by fever, leukocytosis and tender erythematous plaques, which show infiltration by mature neutrophils[ncbi.nlm.nih.gov] Other pathologic changes were pleural effusion (left, 800 ml: right, 1200 ml), acute liver congestion, prostatic hypertrophy, colon adenoma, and hypercellular bone marrow.[ncbi.nlm.nih.gov] Results are often non-specific and include leukocytosis and elevated erythrocyte sedimentation rate (ESR).[symptoma.com]

  • Acute Lymphoblastic Leukemia

    The leukemic cells of the hypercellular bone marrow then spill into the blood circulation and are visible on routine CBCs .[lecturio.com] , hematological, and immunocytological) parameters pointed towards a diagnosis of Wilms tumor in our case, the subsequent development of thrombocytopenia and lymphocytic leukocytosis[ncbi.nlm.nih.gov] A complete blood count returns with leukocytosis of 110,000. Subsequently, a bone marrow biopsy reveals 30% lymphoblasts.[step2.medbullets.com]

  • Hereditary Spherocytosis

    It also results in leukocytosis and thrombocytosis. On peripheral blood smear, spherocytes are unchanged or may even increase.[medcaretips.com]

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