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63 Possible Causes for Hypercellular Bone Marrow, Mean Corpuscular Volume Decreased

  • Polycythemia Vera

    bone marrow 5.[] Based on the presence of severe hypercellularity of the bone marrow and positivity for the JAK2V617F mutation, we finally diagnosed the patient with PV.[] Bone marrow biopsy showing hypercellularity for age with trilineage growth (panmyelosis) including prominent erythroid, granulocytic and megakaryocytic proliferation with[]

  • Myeloproliferative Disease

    The chronic myeloproliferative diseases are characterized by relatively effective hematopoiesis, which results in a hypercellular bone marrow and elevation of one or more[] Image shows: PV bone marrow (hypercellular) Picture of normal bone marrow for comparison Myeloproliferative Disorders: -Polycythemia Vera (PV) * Peripheral blood findings[] Bone marrow histology shows hypercellularity in most of these disorders. In the case of myelofibrosis, bone marrow fibrosis is demonstrated on the reticulin stain.[]

  • Paroxysmal Nocturnal Hemoglobinuria

    Bone marrow failure is present in all patients with PNH, even when peripheral blood counts are normal and the bone marrow is hypercellular.[] Concerned with the apparent intravascular hemolysis, a bone marrow biopsy showed hypercellularity and normal cytogenetics.[] The degree of marrow failure may vary from severe aplastic anemia to a decrease in the number of hematopoietic stem cells.[]

  • Acquired Spherocytosis

    The RDW can be used, along with the mean corpuscular volume to identify the presence and cause of anemia.[] Bone marrow biopsy was hypercellular with a decreased M:E ratio and dysplastic erythroid precursors.[] Limitations : Alcohol abuse can lead to an increased RDW while rheumatoid arthritis can lead to a decreased RDW.[]

  • Hereditary Spherocytosis

    […] cell volume ( MCV ) within normal range ( 80-100 fL ) or slightly decreased Mean corpuscular hemoglobin concentration ( MCHC ) Red blood cell distribution width ; ( RDW )[] Finally, mean corpuscular volume (MCV) usually is normal, except in cases of severe HS, when MCV is slightly decreased.[] corpuscular volume was 86 fl; mean corpuscular hemoglobin was 32.1 pg; mean corpuscular hemoglobin concentration was 37.5%; and platelet count was 84   10 9 /l.[]

  • Cooley's Anemia

    Average size of RBCs (mean corpuscular volume, MCV)—decreased Average amount of hemoglobin in RBCs (mean corpuscular hemoglobin, MCH)—decreased Hemoglobin concentration (mean[] People who have alpha thalassemia trait have red blood cells (RBCs) that are smaller ( microcytic ) and paler ( hypochromic ) than normal, have a decreased MCV (mean corpuscular[] volume, a measurement of the average size of a single RBC), and have a mild chronic anemia .[]

  • Chronic Hemorrhage

    To report a rare case of myeloid sarcoma infiltration of an aortic stent-graft causing chronic hemorrhage and mimicking stent-graft infection. A 90-year-old man presented 8 years after endovascular aneurysm repair with general malaise, nausea, abdominal pain, and hyperbilirubinemia. His inflammatory blood markers[…][]

  • Sideroblastic Anemia

    Initial workup revealed hemoglobin 2.6 g/dL (10.2-12.7), hematocrit 7.7% (30.9-37.9), mean corpuscular volume 104 fL (71.3-82.6), white blood cell count 4200/μL (240 absolute[] Bone Marrow Core Biopsy Bone marrow core biopsy showing hypercellular marrow with erythroid hyperplasia[] Patients usually have a mild asymptomatic anaemia or a borderline decreased mean corpuscular volume. Blood film examination showed Pappenheimer bodies.[]

  • Megaloblastic Anemia

    In the p.o. group, at days 30 and 90, all hematologic parameters changed significantly versus day 0 (mean hemoglobin levels increased [both P 0.001]; mean corpuscular volume[] Megaloblastic anemia, a condition that can be congenital or acquired, is associated with a hypercellular bone marrow with large, abnormal hematopoetic progenitor cells (megaloblasts[] Pathology reported hypercellular bone marrow possibly related with megaloblastic anemia.[]

  • Chronic Eosinophilic Leukemia

    Histology Hypercellular bone marrow with predominatnt eosinophilic proliferation, the number of myeloblasts may be increased between 5 – 19%, Charcot-Leyden crystals are often[] […] their precursors (c) Bone marrow core biopsy showing hypercellularity with a greater than 90% cell to fat ratio (d) Bone marrow core biopsy demonstrating sheets of eosinophils[] Lynh Nguyen (bone marrow biopsy): Numerous eosinophilic precursors Myeloid preponderance Marked hypercellularity Granulocytic hyperplasia Reticulin fibrosis AFIP images (from[]

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