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70 Possible Causes for Hypercellular Bone Marrow, Monocyte Count Increased

  • Leukemia

    Leucocytosis is present in 30–50 % of cases of TAM and typically includes increased neutrophils, myelocytes, monocytes and basophils [ 11 ••, 31, 33 ••].[doi.org] Bone marrow aspirate showed hypercellularity with increased myelopoiesis and markedly suppressed megakaryopoiesis giving an impression of acute myeloid leukemia and was confirmed[ncbi.nlm.nih.gov] Another important feature of bone marrow samples is its cellularity. Normal bone marrow contains hematopoietic (blood-forming) cells and fat cells.[web.archive.org]

  • Myeloproliferative Disease

    The chronic myeloproliferative diseases are characterized by relatively effective hematopoiesis, which results in a hypercellular bone marrow and elevation of one or more[clinlabnavigator.com] Bone marrow histology shows hypercellularity in most of these disorders. In the case of myelofibrosis, bone marrow fibrosis is demonstrated on the reticulin stain.[emedicine.com] This is in contrast to the myelodysplastic syndromes, in which the bone marrow is hypercellular, but the production is ineffective in one or more cell lines, resulting in[clinlabnavigator.com]

  • Acute Leukemia

    The leukocyte count is usually increased monocytic cells (monoblast, promoncytes, monocytes), are increased to 5000/L or more.[intechopen.com] ALL : Hypercellular bone marrow Numerous tightly packed lymphoblasts with undetectable cytoplasm, round, irregular, cleaved nuclei, dispersed chromatin, small nucleoli B[pathologyoutlines.com] Bone marrow aspirate examination revealed hypercellularity with 70% blast cells.[ncbi.nlm.nih.gov]

  • Autoimmune Hemolytic Anemia

    Subsequently, the patient underwent a bone marrow biopsy that showed a hypercellular marrow with erythroid hyperplasia, but no evidence of dysplasia or lymphoma.[dx.doi.org]

  • Polycythemia Vera

    bone marrow 5.[slideshare.net] Based on the presence of severe hypercellularity of the bone marrow and positivity for the JAK2V617F mutation, we finally diagnosed the patient with PV.[ncbi.nlm.nih.gov] Bone marrow biopsy showing hypercellularity for age with trilineage growth (panmyelosis) including prominent erythroid, granulocytic and megakaryocytic proliferation with[pathologyoutlines.com]

  • Cooley's Anemia

    Abstract To examine the relationship between myocardial storage iron and body iron burden, as assessed by hepatic storage iron measurements, we studied 22 patients with transfusion-dependent thalassemia syndromes, all being treated with subcutaneous deferoxamine, and 6 healthy subjects. Study participants were[…][ncbi.nlm.nih.gov]

  • Sickle Cell Disease

    Orthop Nurs. 2018 Jul/Aug;37(4):221-227. doi: 10.1097/NOR.0000000000000464. Author information 1 Irina Benenson, DNP, APN, Rutgers School of Nursing, Newark, NJ. Sallie Porter, DNP, PhD, APN, Rutgers School of Nursing, Newark, NJ. Abstract Sickle cell disease (SCD) is a group of inherited disorders caused by a mutation[…][ncbi.nlm.nih.gov]

  • Infectious Mononucleosis

    A bone marrow aspirate ruled out haemophagocytic syndrome.[ncbi.nlm.nih.gov] Urinalysis showed hypercellularity, with extensive tubular epithelial cells, granular casts and amorphous material.[ncbi.nlm.nih.gov]

  • Chronic Myelomonocytic Leukemia

    The Mayo prognostic model classified CMML patients into three risk groups based on: increased absolute monocyte count, presence of circulating blasts, hemoglobin 9 /L.[mayoclinic.pure.elsevier.com] marrow biopsy: Markedly hypercellular marrow Bone marrow smear: Increased monocytes and monocyte precursors Increase in monocyte precursors and erythroid cytoplasmic vacuoles[pathologyoutlines.com] She had increased monocyte cell count (1.82   10/L), markedly decreased platelet count (2   10/L), hypercellularity of the megakaryocyte lineage with many immature megakaryocytes[ncbi.nlm.nih.gov]

  • Acute Myelocytic Leukemia

    JMML characteristically presents with hepatosplenomegaly, lymphadenopathy, fever, and skin rash along with an elevated white blood cell (WBC) count and increased circulating[northshore.org] The presence of “dry tap” indicates the presence of extensive fibrosis or hypercellular bone marrow.[lecturio.com] marrow biopsy: Markedly hypercellular marrow with heterogeneous cells, including immature monocytes (irregular nuclei and prominent nucleoli) and neutrophils Stains: Chloroacetate[pathologyoutlines.com]

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