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173 Possible Causes for Hypercellular Bone Marrow, Pruritus

  • Polycythemia Vera

    bone marrow 5.[slideshare.net] A detailed MEDLINE search for all English language articles related to PV, PV-associated pruritus and aquagenic pruritus that were published from 1965 till date was carried[ncbi.nlm.nih.gov] Based on the presence of severe hypercellularity of the bone marrow and positivity for the JAK2V617F mutation, we finally diagnosed the patient with PV.[ncbi.nlm.nih.gov]

  • Myeloproliferative Disease

    The chronic myeloproliferative diseases are characterized by relatively effective hematopoiesis, which results in a hypercellular bone marrow and elevation of one or more[clinlabnavigator.com] Common symptoms include: headaches blurred vision fatigue weakness dizziness itchiness (pruritus) night sweats raised blood pressure (hypertension).[leukaemia.org.au] Constitutional symptoms, such as weight loss, fever, and pruritus, also can occur.[clevelandclinicmeded.com]

  • Hereditary Spherocytosis

    A 18 year old Turkish patient with hereditary spherocytosis was admitted to hospital with pruritus and severe jaundice.[ncbi.nlm.nih.gov] Treatment with ursodesoxycholic acid and intermittent therapy with prednisone reduced pruritus and jaundice with concomitant improvement of blood test.[ncbi.nlm.nih.gov]

  • Leukemia

    Bone marrow aspirate showed hypercellularity with increased myelopoiesis and markedly suppressed megakaryopoiesis giving an impression of acute myeloid leukemia and was confirmed[ncbi.nlm.nih.gov] Another important feature of bone marrow samples is its cellularity. Normal bone marrow contains hematopoietic (blood-forming) cells and fat cells.[web.archive.org] Marrow with too many blood-forming cells is said to be hypercellular. If too few of these cells are found, the marrow is called hypocellular.[web.archive.org]

  • Paroxysmal Nocturnal Hemoglobinuria

    These patients tend to have a normocellular to hypercellular bone marrow with erythroid hyperplasia, an elevated reticulocyte count, a large population of PNH cells (usually[bloodjournal.org] Thrombosis is the leading cause of death, but others may die of complications of bone marrow failure, renal failure, myelodysplastic syndrome, and leukemia.[bloodjournal.org]

  • Ayerza Syndrome

    Ayerza syndrome is named after Abel Ayerza and encompasses the clinical features of pulmonary hypertension. It is a progressive disease with mixed etiology, characterized by increased resistance in the pulmonary blood vessels. Ayerza syndrome (AS) describes the signs of pulmonary (arterial) hypertension. It is[…][symptoma.com]

  • Altitude Sickness

    Altitude sickness, the mildest form being acute mountain sickness (AMS), is the negative health effect of high altitude, caused by rapid exposure to low amounts of oxygen at high elevation. Symptoms may include headaches, vomiting, tiredness, trouble sleeping, and dizziness. Acute mountain sickness can progress to[…][en.wikipedia.org]

  • Diabetes Mellitus

    The bone marrow aspiration revealed hypercellular marrow with megaloblastic changes and more than 15% ring sideroblasts.[ncbi.nlm.nih.gov] Symptoms develop 30 min to 2 h after injection and include urticaria, angioedema, pruritus, bronchospasm, and anaphylaxis.[msdmanuals.com] […] outweighed by the benefits of reducing cardiovascular risk. [ 8 ] Presentation Patients with all types of diabetes may present with polyuria, polydipsia, lethargy, boils, pruritus[patient.info]

  • Secondary Polycythemia

    The renal biopsy revealed membranous nephropathy, and the bone marrow biopsy disclosed hypercellular marrow with mild panhyperplasia.[ncbi.nlm.nih.gov] There may generalized pruritus. The spleen may be palpable in 75% of the cases. Gout may be seen due to a raised level of uric acid.[labpedia.net] She had no history of blood clots, deep vein thrombosis or pulmonary embolism, miscarriages, leg swelling, pruritus, tingling, numbness, stroke or transient ischemic attacks[healio.com]

  • Paraneoplastic Syndrome

    Pancytopenia with a hypercellular bone marrow as a possible paraneoplastic syndrome. Am. J. Hematol. 19, 205–206 (1985). 37. Cooper, D. L., Sandler, A. B., Wilson, L.[doi.org] This 59-year-old man developed ophthalmoplegia, dysarthria, dysphagia, pruritus, ataxia, corticobulbar and corticospinal signs in association with prostate cancer.[ncbi.nlm.nih.gov]

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