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133 Possible Causes for Hypercellular Bone Marrow, Reticulocytes Increased

  • Chronic Myeloid Leukemia

    marrow biopsy: Moderately hypercellular bone marrow biopsy with numerous megakaryocytes Increased reticulin fibers (reticulin stain) Marked hypercellularity Myeloblastic[pathologyoutlines.com] Because of such abnormal shapes, these cells are destroyed before releasing into the peripheral blood circulation, leading to cytopenias and hypercellular bone marrow.[lecturio.com] marrow Early myeloid cells (eg, myeloblasts, myelocytes, metamyelocytes, nucleated red blood cells) Bone marrow findings Ph chromosome (a reciprocal translocation of chromosomal[emedicine.medscape.com]

  • Paroxysmal Nocturnal Hemoglobinuria

    Erythrocytes fractionated by centrifugation revealed increased glycolytic enzyme activities of hexokinase, G3PD, PGK, TPI, PK, LDH, G6PD, and 6PGD in the reticulocyte-rich[pediatrics.aappublications.org] Bone marrow failure is present in all patients with PNH, even when peripheral blood counts are normal and the bone marrow is hypercellular.[emedicine.medscape.com] Concerned with the apparent intravascular hemolysis, a bone marrow biopsy showed hypercellularity and normal cytogenetics.[medbullets.com]

  • Polycythemia Vera

    […] hemoglobin or hematocrit Red blood cell morphology is unremarkable except in cases with concomitant iron deficiency Deeply basophilic reticulocytes or rare normoblasts may[pathologyoutlines.com] bone marrow 5.[slideshare.net] Based on the presence of severe hypercellularity of the bone marrow and positivity for the JAK2V617F mutation, we finally diagnosed the patient with PV.[ncbi.nlm.nih.gov]

  • Chronic Phase of Chronic Myeloid Leukemia

    marrow biopsy: Moderately hypercellular bone marrow biopsy with numerous megakaryocytes Increased reticulin fibers (reticulin stain) Marked hypercellularity Myeloblastic[pathologyoutlines.com] A bone marrow biopsy and aspiration demonstrated a hypercellular marrow with no other significant morphologic abnormalities.[hematologyandoncology.net] marrow Early myeloid cells (eg, myeloblasts, myelocytes, metamyelocytes, nucleated red blood cells) Bone marrow findings Ph chromosome (a reciprocal translocation of chromosomal[emedicine.medscape.com]

  • Acquired Spherocytosis

    A complete blood count (CBC) may show increased reticulocytes, a sign of increased red blood cell production, and decreased hemoglobin and hematocrit.[en.wikipedia.org] Bone marrow biopsy was hypercellular with a decreased M:E ratio and dysplastic erythroid precursors.[bloodjournal.org] If the reticulocyte count is low, the body is not able to keep up with the increased red blood cell production demands.[ihtc.org]

  • Pyruvate Kinase Deficiency

    Char10C mice also display a reduction in anemia phenotypes associated with the PklrG338D mutation including decreased splenomegaly, decreased circulating reticulocytes, increased[ncbi.nlm.nih.gov] As a result of splenectomy, reticulocyte counts often increase and transfusion needs are reduced.[orpha.net] The increased 2,3-DPG levels ameliorate the anemia by lowering the oxygen-affinity of hemoglobin.[orpha.net]

  • Hereditary Spherocytosis

    , Reticulocyte count decreased 4 MCV increased, MCHC increased, Reticulocyte count decreased 5 MCV increased, MCHC decreased, Reticulocyte count increased M2 Select Answer[medbullets.com] Reticulocyte count: Increased Treatment: Splenectomy is indicated for moderate to severe cases, but not mild cases.[medical-labs.net] Review Topic QID: 104666 1 MCV normal, MCHC increased, Reticulocyte count increased 2 MCV normal, MCHC decreased, Reticulocyte count decreased 3 MCV normal, MCHC increased[medbullets.com]

  • Autoimmune Hemolytic Anemia

    Over the course of the next 5 days, the Hb and Hct decreased to 4.1 g/dL and 12%, respectively, direct bili increased to 12.3 mg/day, reticulocytes slightly increased to 0.9%[ncbi.nlm.nih.gov] Laboratory data showed low hemoglobin levels and slightly increased reticulocyte counts, while direct and indirect antiglobulin tests were positive.[ncbi.nlm.nih.gov] A 36-year-old woman presented with hemolytic anemia without a reticulocyte response 38 days after delivery.[ncbi.nlm.nih.gov]

  • Congenital Hemolytic Anemia

    The alpha-, and beta-globin mRNA content of the reticulocytes after interleukin-3 incubation, as measured by RT-PCR, increased.[ncbi.nlm.nih.gov] After partial splenectomy, children overall had decreased transfusion requirements, increased hematocrits, decreased bilirubin levels, decreased reticulocyte counts, and elimination[ncbi.nlm.nih.gov] As a result of splenectomy, reticulocyte counts often increase and transfusion needs are reduced.[orpha.net]

  • Cold Agglutinin Disease

    Typical bloodwork results would show: decreased hemoglobin (due to the red cell lysis) increased reticulocyte count (reflecting the marrow kicking red cell production into[transfusion.ca] Figure 2 Bone marrow biopsy. A. Low magnification (10 x) view of a slightly hypercellular bone marrow with groups (circled) and scattered large lymphoma cells. B.[ispub.com] […] breakdown Indirect/ unconjugated bilirubin Reticulocytes : loss of erythrocytes reactive increase in erythropoiesis increase in reticulocytes in the peripheral blood In extreme[amboss.com]

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