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95 Possible Causes for Hypercellular Bone Marrow, Uric Acid Increased

  • Leukemia

    Bone marrow aspirate showed hypercellularity with increased myelopoiesis and markedly suppressed megakaryopoiesis giving an impression of acute myeloid leukemia and was confirmed[ncbi.nlm.nih.gov] acid. 21 Immunosuppression from chemotherapy, hematopoietic stem cell transplantation, or the leukemia itself may increase the risk of serious infections.[aafp.org] Another important feature of bone marrow samples is its cellularity. Normal bone marrow contains hematopoietic (blood-forming) cells and fat cells.[web.archive.org]

  • Myeloproliferative Disease

    The chronic myeloproliferative diseases are characterized by relatively effective hematopoiesis, which results in a hypercellular bone marrow and elevation of one or more[clinlabnavigator.com] Furthermore, ruxolitinib also decreased plasma levels of N-terminal pro-brain natriuretic peptide, von Willebrand antigen, ristocetin-cofactor activity and uric acid, and[err.ersjournals.com] Bone marrow histology shows hypercellularity in most of these disorders. In the case of myelofibrosis, bone marrow fibrosis is demonstrated on the reticulin stain.[emedicine.com]

  • Chronic Myeloid Leukemia

    marrow biopsy: Moderately hypercellular bone marrow biopsy with numerous megakaryocytes Increased reticulin fibers (reticulin stain) Marked hypercellularity Myeloblastic[pathologyoutlines.com] Gout – increased cell turnover excess purines broken down to uric acid Increased susceptibility to infections – functional immune cells Shortness of breath/fatigue – anaemia[geekymedics.com] Sodium bicarbonate may be used to alkalinize the urine to increase uric acid excretion.[lecturio.com]

  • Polycythemia Vera

    bone marrow 5.[slideshare.net] Based on the presence of severe hypercellularity of the bone marrow and positivity for the JAK2V617F mutation, we finally diagnosed the patient with PV.[ncbi.nlm.nih.gov] Severe continuous small joint pain Patients will present with symptoms of gout as a result of increased uric acid production. Gout mainly affects big toe.[medicaljoyworks.com]

  • Chronic Phase of Chronic Myeloid Leukemia

    marrow biopsy: Moderately hypercellular bone marrow biopsy with numerous megakaryocytes Increased reticulin fibers (reticulin stain) Marked hypercellularity Myeloblastic[pathologyoutlines.com] acid – gout/uropathy Histamine increase with basophil 90% In normal cells, two red and two green signals indicate the location of the normal ABL and BCR genes, respectively[slideshare.net] A bone marrow biopsy and aspiration demonstrated a hypercellular marrow with no other significant morphologic abnormalities.[hematologyandoncology.net]

  • Hereditary Spherocytosis

    From Wikidata Jump to navigation Jump to search congenital hemolytic anemia characterized by the production of red blood cells with a sphere shape, rather than the normal biconcave disk shape Congenital spherocytic hemolytic anemia Minkowski Chauffard syndrome spherocytic anemia edit English hereditary[…][wikidata.org]

  • Pernicious Anemia

    An elderly black man was admitted to our institution with macrocytic anemia, dysphagia, and significant weight loss. Results of an esophagogram were suggestive of achalasia. Gastric adenocarcinoma infiltrating the gastric cardia was seen on gastroscopy. The mode of presentation of gastric cancer in this case has[…][ncbi.nlm.nih.gov]

  • Autoimmune Hemolytic Anemia

    Subsequently, the patient underwent a bone marrow biopsy that showed a hypercellular marrow with erythroid hyperplasia, but no evidence of dysplasia or lymphoma.[jmedicalcasereports.com]

  • Sickle Cell Disease

    Delayed hemolytic transfusion reaction (DHTR) is a life-threatening complication in patients with sickle cell disease, characterized by difficulties in diagnosis and management. Certain reports have suggested successful salvage treatment with the terminal complement inhibitor, eculizumab. We here report evidence of[…][ncbi.nlm.nih.gov]

  • Diabetes Mellitus

    The bone marrow aspiration revealed hypercellular marrow with megaloblastic changes and more than 15% ring sideroblasts.[ncbi.nlm.nih.gov] […] lowering uric acid levels prevented the increase in mean arterial blood pressure ( 40 ).[doi.org] […] whereas uric acid (HR per 1 mmol/L increase, 2.05) and physical inactivity during leisure time (HR, 1.80) were associated with diabetes development in women only.[doi.org]

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