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360 Possible Causes for Hypercellular Bone Marrow, Weight Loss

  • Leukemia

    The common symptoms of the disease include the following: Undue weight loss Constant felling of tiredness and fatigue Pain in bone Fever accompanied by chills Excessive sweating[symptoma.com] Bone marrow aspirate showed hypercellularity with increased myelopoiesis and markedly suppressed megakaryopoiesis giving an impression of acute myeloid leukemia and was confirmed[ncbi.nlm.nih.gov] Another important feature of bone marrow samples is its cellularity. Normal bone marrow contains hematopoietic (blood-forming) cells and fat cells.[web.archive.org]

  • Myeloproliferative Disease

    Splenomegaly, hepatomegaly as well as fatigue, malaise or weight loss may appear in advanced stages.[orpha.net] The chronic myeloproliferative diseases are characterized by relatively effective hematopoiesis, which results in a hypercellular bone marrow and elevation of one or more[clinlabnavigator.com] The clinical picture in early stages is often nonspecific with symptoms including fatigue, weight loss and anorexia.[symptoma.com]

  • Pernicious Anemia

    An elderly black man was admitted to our institution with macrocytic anemia, dysphagia, and significant weight loss.[ncbi.nlm.nih.gov] loss, progressive weakness, ataxia, and visual impairment.[ncbi.nlm.nih.gov] These symptoms include nausea (feeling sick to your stomach) and vomiting, heartburn, abdominal bloating and gas, constipation or diarrhea, loss of appetite, and weight loss[web.archive.org]

  • Chronic Myeloid Leukemia

    Patients usually present with fatigue, weight loss, anemia, night sweats, and splenomegaly.[icd9data.com] marrow biopsy: Moderately hypercellular bone marrow biopsy with numerous megakaryocytes Increased reticulin fibers (reticulin stain) Marked hypercellularity Myeloblastic[pathologyoutlines.com] People pass through a phase in which they have nonspecific symptoms such as tiredness, loss of appetite, and weight loss.[merck.com]

  • Chronic Phase of Chronic Myeloid Leukemia

    In the accelerated phase, the number of CML cells is growing faster and causing symptoms such as fatigue, fever, weight loss and an enlarged spleen.[lls.org] marrow biopsy: Moderately hypercellular bone marrow biopsy with numerous megakaryocytes Increased reticulin fibers (reticulin stain) Marked hypercellularity Myeloblastic[pathologyoutlines.com] These patients often have fever, poor appetite, and weight loss. In this phase, the CML acts a lot like an acute leukemia.[cancer.org]

  • Polycythemia Vera

    Palpable splenomegaly is one of the worst offenders since it contributes to early satiety, bloating, pain, portal hypertension, weight loss, and exacerbation of cytopenia.[medpagetoday.com] bone marrow 5.[slideshare.net] Based on the presence of severe hypercellularity of the bone marrow and positivity for the JAK2V617F mutation, we finally diagnosed the patient with PV.[ncbi.nlm.nih.gov]

  • Acute Leukemia

    Symptoms of ALL include: Weakness or feeling tired Fever Easy bruising or bleeding Bleeding under the skin Shortness of breath Weight loss or loss of appetite Pain in the[nlm.nih.gov] ALL : Hypercellular bone marrow Numerous tightly packed lymphoblasts with undetectable cytoplasm, round, irregular, cleaved nuclei, dispersed chromatin, small nucleoli B[pathologyoutlines.com] Both leukemia itself and the treatment can lead to many problems such as bleeding, weight loss, and infections.[medlineplus.gov]

  • Vitamin B12 Deficiency

    We present a 73-year-old individual with weight loss and anemia.[ncbi.nlm.nih.gov] Untreated B 12 deficiency can cause hypercellular and dysplastic bone marrow, which can be mistaken for signs of acute leukemia.[pharmacytimes.com] We report an adolescent girl who presented with jaundice and weight loss for 6 months secondary to vitamin B12 deficiency, leading to megaloblastic anaemia.[ncbi.nlm.nih.gov]

  • Anemia

    […] of appetite, weight loss, fatigue and anemia, per the CDC. — Maggie O'neill, Health.com, "What Is Hookworm?[merriam-webster.com] Clinics RA usually presents with hypercellular bone marrow (BM) and anemia.[atlasgeneticsoncology.org] Researchers ... read more Long-Term Follow-Up After Weight-Loss Surgery Finds High Rate of Anemia Sep. 20, 2017 — Researchers found a high rate of anemia 10 years after patients[sciencedaily.com]

  • Primary Myelofibrosis

    Constitutional symptoms, such as night sweats, pruritus, weight loss and fever may be treated with Jakafi.[mpnresearchfoundation.org] A biopsy of the lytic lesion was done, revealing hypercellular bone marrow with hyperplastic granulopoiesis associated with megakaryocytic proliferation and atypia, accompanied[ncbi.nlm.nih.gov] There is a stepwise evolution from an initial pre/fibrotic early stage, characterized by hypercellular bone marrow with absent or minimal reticulin fibrosis, to an overt fibrotic[seer.cancer.gov]

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