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56 Possible Causes for Hypercellular Bone Marrow with Erythroid Hyperplasia

  • Gastritis

    Bone marrow biopsy revealed hypercellular bone marrow with marked erythroid hyperplasia, megaloblastic changes, and a left shift in myeloid maturation with many bands consistent[casesjournal.biomedcentral.com]

  • Paroxysmal Nocturnal Hemoglobinuria

    These patients tend to have a normocellular to hypercellular bone marrow with erythroid hyperplasia, an elevated reticulocyte count, a large population of PNH cells (usually[doi.org]

  • Refractory Anemia

    marrow : hypercellular or normocellular Erythroid : erythroid hyperplasia, may have mild to moderate dysplasia with megaloblastoid features; 15% ringed sideroblasts Myeloid[pathologyoutlines.com] A bone marrow aspirate and biopsy revealed a hypercellular bone marrow with marked hyperplasia of erythroid series with 15% ringed sideroblasts, and 3 iron on Prussian blue[omicsonline.org] Bone marrow biopsy showed a hypercellular marrow for age (70%) with trilineage hematopoiesis and erythroid hyperplasia (M: E ratio 0.9:1).[ijcasereportsandimages.com]

  • Malignant Angioendotheliomatosis

    A bone marrow ex- amination showed hypercellularity with erythroid hyperplasia. The Coombs test and sucrose and acid hemolysis determinations were negative.[myslide.es]

  • Drug Hypersensitivity

    […] biopsy 5 showed hypocellularity with decreased myeloid and erythroid series, all showed increased megakaryocytes and interstitial infiltration 1 showed hypercellularity and[ncbi.nlm.nih.gov] […] diagnosed as EM 2 (12%)—only perivascular inflammation by mixed cells 1 (6%)—lymphocytic vasculitis 1 (6%)—pigment incontinence without obvious interface activity 6 underwent bone-marrow[ncbi.nlm.nih.gov] […] increased M/E ratio to 5:1 with myeloid hyperplasia Elevated liver enzymes—48 (80%) Renal involvement—24 (40%) Lung involvement—20 (33%) Cardiac involvement—9 (15%) Pancreas[ncbi.nlm.nih.gov]

  • Refractory Anemia with Excess Blasts in Transformation

    MDS Peripheral Blood Bone Marrow Refractory anemia (RA) anemia (macrocytic or dimorphic) with reticulocytopenia; variable dyserythropoiesis; normal - hypercellular; erythroid[med-ed.virginia.edu] marrow Erythroid hyperplasia in marrow Refractory anemia with excess of blasts (RAEB) 5-19% blasts in the bone marrow Peripheral blood Neutrophil abnormalities common Usually[thedoctorsdoctor.com] hyperplasia with variable dyserythropoiesis; normal myeloid & megakaryocytic lines; Refractory anemia with ringed sideroblasts (RAS) anemia (macrocytic or dimorphic) with[med-ed.virginia.edu]

  • Microcytic Anemia

    .  HypercellularErythroid hyperplasia  M:E ratio 1:5  Dyserythropoisis  Myelopoisis and megakaryopoisis are normal  Bone marrow iron increased Dr.[slideshare.net]

  • Leukoerythroblastic Anemia

    Only eight patients gave consent for bone marrow aspiration. All marrows were hypercellular, showing erythroid hyperplasia with megaloblastic erythropoiesis (100%).[jahjournal.org] Giant metamyelocytes were seen in all the bone marrow. The iron stores were reduced (Grade 0–1 ) in only one case and increased in seven cases.[jahjournal.org]

  • Hereditary Sideroblastic Anemia

    Bone Marrow Core Biopsy Bone marrow core biopsy showing hypercellular marrow with erythroid hyperplasia[imagebank.hematology.org] marrow general : hypercellular or normocellular marrow with erythroid hyperplasia Bone marrow erythroid : erythroid hyperplasia, may be mild to moderate dysplasia; markedly[pathologyoutlines.com] Aspirate Bone marrow aspirate showing erythroid hyperplasia Iron Stain The iron stain shows ringed sideroblasts.[imagebank.hematology.org]

  • Congenital Dyserythropoietic Anemia

    The bone marrow is hypercellular with erythroid hyperplasia but, contrary to CDA I, is of normoblastic appearance with a large number of binucleate (10-35%) and rarely multinucleate[doi.org] Bone marrow specimens showed distinct hypercellularity due to erythroid hyperplasia.[doi.org] Specific abnormalities of CDA II All 48 patients had typical bone marrow findings and laboratory evidence of ineffective erythropoiesis.[doi.org]

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