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491 Possible Causes for Hyperchromatic Nuclei

  • Infectious Mononucleosis

    nuclei).[doi.org] , the paracortical areas usually show a mixture of small and large lymphoid cells, but without significant cytologic atypia (the latter manifested by highly irregular or hyperchromatic[doi.org]

  • Childhood Soft Tissue Sarcoma

    Large, lobulated, and hyperchromatic nuclei as well as atypical mitoses are characteristic of undifferentiated, pleomorphic rhabdomyosarcoma.[symptoma.com]

  • Pleomorphic Rhabdomyosarcoma

    Fine needle aspiration biopsy of a lytic lesion in the right iliac wing showed a pleomorphic population of clusters and single cells with hyperchromatic nuclei; granular,[ncbi.nlm.nih.gov] nuclei.[basicmedicalkey.com] Anaplastic malignant neoplasm composed of proliferating atypical spindle cells with pleomorphic and hyperchromatic nuclei and eosinophilic cytoplasm, with scattered giant[acgcasereports.gi.org]

  • Villous Adenoma of the Colon

    nuclei, (pseudo)stratified nuclei, nucleolus, decreased mucosecretion and mitosis.[pathologyatlas.ro] hyperchromatic and elongated in shape; stratification of nuclei; varies degree of dysplasia.[pathology.class.kmu.edu.tw] LM nuclear changes - esp. at the surface (hyperchromatic elongated nuclei or round cleared nuclei), nuclear crowding/pseudostratification, /- loss of nuclear polarity, loss[librepathology.org]

  • Translocation Renal Cell Carcinoma

    Fine-needle aspiration of the lymph node showed tumor cells with voluminous clear to eosinophilic cytoplasm, well-defined cell borders and hyperchromatic nuclei arranged in[ncbi.nlm.nih.gov] (b) Cells with abundant pale to vacuolated cytoplasm and hyperchromatic nuclei (Geimsa x400).[ijpmonline.org] The cells were large, round to polygonal with abundant, finely granular or clear - vacuolated cytoplasm and moderately enlarged, round, hyperchromatic nuclei with occasional[ijpmonline.org]

  • Desmoplastic Small Round Cell Tumor

    The tumor cells were medium sized, with hyperchromatic nuclei and moderate amounts of cytoplasm.[ncbi.nlm.nih.gov] Fine-needle aspiration cytology showed variably cohesive clusters of small cells with hyperchromatic nuclei and fine granular chromatin.[ncbi.nlm.nih.gov] Biopsy of the mass shows nests of poorly differentiated small round cells with little cytoplasm and hyperchromatic nuclei that are surrounded by desmoplastic stroma.[orpha.net]

  • Papillary Serous Cystadenocarcinoma of the Ovary

    The tumor cells were large with small hyperchromatic nuclei and abundant clear cytoplasm [Figure 2] b and d.[ijpmonline.org] Figure 1: Small groups of cells with enlarged and hyperchromatic nuclei (400x).[omicsonline.org] Furthermore, seen are few bizarre cells with irregular hyperchromatic nuclei and atypical mitosis (6-8/10 hpf). Numerous psammoma bodies were also seen [Figure 3] .[ccij-online.org]

  • Gastric Leiomyosarcoma

    Data which favor the diagnosis of leiomyosarcoma are: (1) spindle-shaped cells with malignant looking nuclei; (2) cells with extremely long, fiber-like cytoplasms and hyperchromatic[ncbi.nlm.nih.gov] Histological examination showed interlacing bundles of spindle cells, ill-defined cell borders, elongated hyperchromatic nuclei with marked pleomorphism and paranuclear vacuolization[ncbi.nlm.nih.gov] The nuclei of the spindle cells were hyperchromatic, pleomorphic and multinucleated [Figure - 3].[saudijgastro.com]

  • Penile Intraepithelial Neoplasia

    Histologic sections reveal epidermal acanthosis and atypical keratinocytes displaying individual cell keratinization and atypical nuclei, including large hyperchromatic nuclei[acupath.com] H&E: note the pleomorphic, hyperchromatic keratinocytes with multiple nuclei and scattered abnormal mitotic figures. Figure 3.[dermatologyadvisor.com] Routine hematoxylin and eosin (H&E) staining will show pleomorphic, hyperchromatic keratinocytes with multiple nuclei and occasional abnormal mitotic figures ( Figure 2 ).[dermatologyadvisor.com]

  • Thyroid Follicular Adenoma

    (large hyperchromatic nuclei in clusters) Rarely contains mature fat ( Mod Pathol 1989;2:506 ), signet ring cells ( Acta Cytol 2004;48:87 ), extensive bone metaplasia ( J[pathologyoutlines.com] In some cases mitoses, bizarre and giant hyperchromatic nuclei found between hyperplastic nodules, and fibrosis with irregularities that may mimic capsular invasion are found[path.upmc.edu] nuclei that lacked features of PTC nuclei.[diagnosticpathology.biomedcentral.com]

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