Create issue ticket

37 Possible Causes for Hyperconvex Nails, Thin Limbs, Widely Spaced Nipples

  • Wolf-Hirschhorn Syndrome

    spaced nipples Hypoplasia or duplication of thumbs and great toes Talipes equinovarus Hypoplasia of pubic bones Vertebral and rib anomalies Defective calvaria ossification[emedicine.medscape.com] [ncbi.nlm.nih.gov] Skin Hyperconvex Nails In the hands, notable features include dermal ridges, simian crease in the palms, and hyperconvex nails .[symptoma.com] spaced nipples Trisomy 9 (usually mosaic) Mental retardation Intrauterine and postnatal growth delay Microcephaly Micrognathia Low-set, malformed ears and other facial anomalies[alpfmedical.info]

  • Fetal Hydantoin Syndrome

    Limbs--joint contractures; missing or abnormal palmar creases; camptodactyly to Trisomy 18 due to severe problems in brain development. They have a mouse model.[carolguze.com] (Fig.1) The baby also had widely spaced small nipple with absent areola and hirisutism.[de.slideshare.net] The nails generally reflect the size and shape of the underlying distal phalanx (e.g., hypoplastic nail, narrow hyperconvex nail, short broad nail). Figure 1.100.[rrnursingschool.biz]

  • Disproportionate Short Stature - Ptosis - Valvular Heart Lesions

    A rare inherited growth disorder characterized by growth retardation, feeding difficulties, failure to thrive, facial abnormalities and asymmetry of limbs.[icd10data.com] spaced nipples Pectus excavatum or pectus carinatum (up to 90% have both, usually pectus carinatum superiorly and pectus excavatum inferiorly) Scoliosis As patients age,[pedclerk.bsd.uchicago.edu] […] hypoplasia, hyperconvex uplifted nails, multiple pigmented nevi, characteristic facies, short 4th metacarpal, high arched palate, or chronic otitis media.” 24 PWS is a rare[cmecorner.com]

  • Growth Failure

    Growth and skeletal asymmetry of the limbs manifested as hemihypertophy, clinodactyly of the fifth finger, syndactyly of second and third toes were also impartant criteria[medcraveonline.com] nipples.[hawaii.edu] […] hypoplasia, hyperconvex uplifted nails, multiple pigmented nevi, characteristic facies, short 4th metacarpal, high arched palate, or chronic otitis media.” 24 PWS is a rare[cmecorner.com]

  • Familial Short Stature

    […] lips and down‐slanted oral commissures) intellectual disability, upper limbs abnormalities and hypertrichosis.[intechopen.com] spaced nipples, pectus excavatum or carinatum, breast development Genitourinary – accurate Tanner staging Anthropometry Growth charts are very helpful for assessing growth[learn.pediatrics.ubc.ca] .  Webbed neck Short metacarpals Shield shaped chest Hyperconvex finger n toe nails Cubitus valgus with wide carrying angle of arms Gonadal dysgenesis with incomplete[slideshare.net]

  • Absent Thumb - Short Stature - Immunodeficiency Syndrome

    Abnormality of retinal pigmentation Fine hair Abnormally ossified vertebrae Abnormal T cell morphology Abnormality of the distal phalanx of finger Disproportionate short-limb[mendelian.co] spaced nipples, and webbed neck?[stuvia.com] A rare inherited growth disorder characterized by growth retardation, feeding difficulties, failure to thrive, facial abnormalities and asymmetry of limbs.[icd10data.com]

  • Congenital Mandibular Hypoplasia

    30,000 CLINICAL DIAGNOSIS, but can test for above mutation Feats (FOB): FACE: microcephaly, synophrys, long eye lashes, long philtrum, low-set ears, short upturned nose, thin[quizlet.com] spaced nipples - cubitus valgus - hyperconvex finger nails - short stature - sexual maturation failure (adrenarche normal, but delayed pubarche, and have premature menopause[quizlet.com] […] finger nails - short stature - sexual maturation failure (adrenarche normal, but delayed pubarche, and have premature menopause (infertile by 2 yo) NORMAL INTELLIGENCE Other[quizlet.com]

  • Renal Malrotation

    Thin sideward extensions of the mesentery connected the intestinal tube with the mesenteric rod (Fig. 5a ).[bmcdevbiol.biomedcentral.com] Chest - broad chest, pectus excavatum, inverted, hypoplastic, widely-spaced nipples. Joints - cubitus valgus, congenital hip dislocation.[patient.info] The 4 th loop (coded blue) developed from the caudal limb of the midgut between the apex and the cecum, and expanded cranially on the left side of the axis.[bmcdevbiol.biomedcentral.com]

  • Schinzel-Giedion Syndrome

    ; Delayed ossification of sutures; Wormian bones; Shallow sella turcica; Absence of mandibular condyles; [Spine]; Winging of scapula; Lordosis; Scoliosis; Spina bifida; [Limbs[findzebra.com] nails mental retardation seizures opisthotonus spasticity hypsarrhythmia cerebral atrophy ventriculomegaly thin corpus callosum hypothryoidism diabetes insipidus tumor predisposition[humpath.com] nail Increased nail curvature Nail overcurvature [ more ] 0001795 Hypertrichosis 0000998 Hypoplasia of first ribs Small first rib Underdeveloped first rib [ more ] 0006657[rarediseases.info.nih.gov]

  • Acrorenal Mandibular Syndrome

    Split foot (unilateral) Varus deformity of the feet Bilateral renal agenesis Ureters Polycystic kidneyes Large cervical spine Sternal deformity Rib hypoplasia (irregular and thin[docksci.com] spaced nipples - cubitus valgus - hyperconvex finger nails - short stature - sexual maturation failure (adrenarche normal, but delayed pubarche, and have premature menopause[quizlet.com] nail Aplasia of the uterus Upper limb undergrowth Ovarian cyst Shawl scrotum Long fingers Language impairment Abnormal lacrimal duct morphology Focal seizures with impairment[mendelian.co]

Similar symptoms