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517 Possible Causes for Hypergammaglobulinemia

  • Multicentric Castleman's Disease

    Multicentric Castleman's disease (MCD) is a rare disorder characterized by fever, polyclonal hypergammaglobulinemia, and generalized lymphadenopathy.[] A 59-year-old man presented with multiple dark red erythemas with induration, anemia, and polyclonal hypergammaglobulinemia.[] Indicators of inflammation were remarkable: she had extremely high levels of serum interleukin-6 (IL-6) (398 pg/ml) in addition to hypergammaglobulinemia and hypoalbuminemia[]

  • Angioedema

    The initial goal of therapy is airway management. The most skilled person available must handle airway interventions because of the often massive degree of oral obstruction that is involved. A definitive airway must be established if edema is extensive or progressing. Most patients with mild acute angioedema may be[…][]

  • Oligoarthritis

    We present a patient in whom a combination of perinuclear antineutrophil cytoplasmic antibody-positive vasculitis, oligoarthritis, tendinitis, and myositis was considered to be associated with isotretinoin use. Discontinuation of the drug resulted in complete clinical and biochemical remission (normalization of perinuclear[…][]

  • Malabsorption Syndrome

    Previously described treatments used for eosinophilic diseases of the gastrointestinal tract have included dietary restrictions primarily of cow milk protein, anti-inflammatory therapy utilizing suplatast, budesonide and corticosteroids, cromolyn sodium, anti-histamines and oral inhalable steroids. We describe a[…][]

  • Thalassemia

    Treatments for thalassemias depend on the type and severity of the disorder. People who are carriers or who have alpha or beta thalassemia trait have mild or no symptoms. They’ll likely need little or no treatment. Doctors use three standard treatments for moderate and severe forms of thalassemia. These[…][]

  • Hereditary Angioedema

    Hereditary and acquired angioedema are of outstanding clinical importance, as edematous attacks associated with these conditions can thrust afflicted patients into mortal danger. Currently, C1 inhibitor concentrate – a human blood product – is available as a replacement therapy. In view of the limited number of[…][]

  • Eosinophilic Fasciitis

    EF is associated with peripheral eosinophilia, hypergammaglobulinemia, and an elevated ESR.[] The acute state of disease is associated with significant peripheral blood eosinophilia, an elevated erythrocyte sedimentation rate and hypergammaglobulinemia.[] Peripheral eosinophilia, poly or monoclonal hypergammaglobulinemia and increased erythrocyte sedimentation rate can be seen.[]

  • Hereditary Angioedema Type 1

    Hereditary angioedema type 1 is an autosomal dominant disease characterized by C1 esterase inhibitor deficiency and the onset of edema, abdominal pain and erythema marginatum. Clinical features of HAE are largely indistinguishable across all types, but type 1 is characterized by a prodromal period in which a[…][]

  • Angioimmunoblastic Lymphadenopathy

    A patient with angioimmunoblastic lymphadenopathy with dysproteinemia had a monoclonal IgG hypergammaglobulinemia.[] Patients with angioimmunoblastic lymphadenopathy (AILD)-type T-cell lymphoma may develop hypergammaglobulinemia.[] Blood analysis revealed an elevated erythrocyte sedimentation rate and polyclonal hypergammaglobulinemia.[]

  • Childhood Non-Small Cell Lung Cancer

    […] characteristic of this type of tumor, and affected children typically present with laboratory findings of chronic inflammation such as leukocytosis, elevated platelet count, hypergammaglobulinemia[]

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