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213 Possible Causes for Hypergammaglobulinemia, Hypoalbuminemia

  • Multicentric Castleman's Disease

    In each case, tocilizumab alleviated symptoms, including generalized fatigue, pyrexia, and alleviated biochemical abnormalities, including anemia, hypoalbuminemia, hypergammaglobulinemia[ncbi.nlm.nih.gov] Multicentric Castleman's disease (MCD) is a rare disorder characterized by fever, polyclonal hypergammaglobulinemia, and generalized lymphadenopathy.[ncbi.nlm.nih.gov] Indicators of inflammation were remarkable: she had extremely high levels of serum interleukin-6 (IL-6) (398 pg/ml) in addition to hypergammaglobulinemia and hypoalbuminemia[ncbi.nlm.nih.gov]

  • Multiple Myeloma

    A 75-year-old man presented with progressive leg edema, had nephrotic range proteinuria, hypoalbuminemia, moderate renal failure, and occult blood in his urine.[ncbi.nlm.nih.gov] Many of these patients had multiple myeloma or macroglobulinemia, but others had no evidence of malignancy and he considered them to have “essential hypergammaglobulinemia[bloodjournal.org] […] recommendations must be followed; however, the threshold for implanting these devices is usually very low, given that other coexisting factors (autonomic neuropathy and hypoalbuminemia[cjasn.asnjournals.org]

  • Renal Amyloidosis

    The laboratory work-up showed nephrotic-range proteinuria and hypoalbuminemia and normal renal function despite bilateral shrunken kidneys revealed by the abdominal ultrasound[ncbi.nlm.nih.gov] […] by multiple extensive reddish-brown plaques showing polyclonal plasma cell infiltrates, and various extracutaneous involvements including lymphadenopathy and polyclonal hypergammaglobulinemia[anndermatol.org] The patient was put on Colchicine and anticoagulants seeing the major hypoalbuminemia.[ecco-ibd.eu]

  • Alcoholic Hepatitis

    A blood test showed leukophilia, mild hypoalbuminemia, hyperbilirubinemia, hepatobiliary injury and coagulopathy.[ncbi.nlm.nih.gov] Patients with alcoholic hepatitis usually show increased liver test results, including gamma-glutamyl transferase (GGT), hypergammaglobulinemia and enlarged liver.[quitalcohol.com] . - Mild elevation in alkaline phosphatase Albumin (frequent hypoalbuminemia) Prothrombin time/international normalized ratio (INR) (frequent coagulopathy) Complete blood[clinicaladvisor.com]

  • Adult-Onset Still Disease

    AOSD patients with RHS showed higher frequencies of leukopenia, anemia, thrombocytopenia, hypoalbuminemia, hypofibrinogenemia, hypertriglyceridemia, hyperferritinemia, and[ncbi.nlm.nih.gov] Liver involvement was observed in all cases, with hepatomegaly in 81.3%, increased liver enzymes in 50.0%, and hypergammaglobulinemia in 68.8%.[ncbi.nlm.nih.gov] Laboratory tests support the inflammatory nature of the disorder with leukocytosis, anemia of chronic disease, hypoalbuminemia, and hyperferritinemia.[rheumnow.com]

  • Polymyalgia Rheumatica

    Other laboratory signs of inflammation may include: thrombocytosis, leukocytosis, anemia, hypoalbuminemia, polyclonal hypergammaglobulinemia, and an elevated ferritin.[rheumatologyadvisor.com] Other laboratory signs of inflammation may include: thrombocytosis, leukocytosis, anemia, hypoalbuminemia, polyclonal hypergammaglobulinemia, and an elevated ferritin.[rheumatologyadvisor.com]

  • Primary Biliary Cirrhosis

    A liver profile test panel showed mild increases in transaminases, increased alkaline phosphatase activity, hypoalbuminemia, significant hyperbilirubinemia, and evidence of[clinchem.aaccjnls.org] […] hepatocellular carcinoma 50% asymptomatic at time of diagnosis -Elevated alkaline phosphatase -Elevated bilirubin (jaundice) suggests progressive disease -Positive AMA, hypergammaglobulinemia[quizlet.com] With progressive liver failure, ascites and hepatosplenomegaly may occur, as well as blood derangements such as hypoalbuminemia and prolonged coagulation times.[consultant360.com]

  • Liver Disease

    Signs/Symptoms of Cirrhotic Decompensation Causes Upper GI bleeding Variceal hemorrhage Confusion Encephalopathy Abdominal distention Ascites Edema Hypoalbuminemia Jaundice[hiv.va.gov] Common features of AIH are hypergammaglobulinemia (IgG), presence of circulating autoantibodies, histological picture of interface hepatitis and response to immunosuppressant[ncbi.nlm.nih.gov] You may also have signs or laboratory findings indicating malnutrition, such as weight loss, edema, anemia, hypoalbuminemia, hypokalemia, hypocalcemia, or hypomagnesemia.[ssa.gov]

  • Malabsorption Syndrome

    ., intestinal lymphangiectasia, Whipple's disease ) Clinical features : hypoalbuminemia with peripheral edema In cases of systemic diseases, symptoms may be those of the underlying[amboss.com] .  Edema  Hypoalbuminemia from chronic protein malabsorption or from loss of protein into the intestinal lumen causes peripheral edema.  Extensive obstruction of the lymphatic[slideshare.net] Waldman et al. [ 77 ] reported the first cases of such intestinal lymphangiectasia, associated with edema and hypoproteinemia (along with hypoalbuminemia and hypogammaglobulinemia[pubs.sciepub.com]

  • Viral Hepatitis

    , a diagnosis of cirrhosis was made if histologic findings of hepatic fibrosis were observed in conjunction with clinical evidence of severe hepatic dysfunction (such as hypoalbuminemia[bmcgastroenterol.biomedcentral.com] False positive results were seen in: --hypergammaglobulinemia. --connective tissue disorders. b) (RIBA) . R ecombinant I mmuno B lot A ssay.[meddean.luc.edu] […] based upon a combination of axial imaging features (including hepatic macronodularity and ascites), serum biochemistries indicative of severe hepatic dysfunction (such as hypoalbuminemia[bmcgastroenterol.biomedcentral.com]

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