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1,223 Possible Causes for Hyperglobulinemia, Immunoglobulin A Decreased, Percentage of Naive B Cells Increased

  • Third Trimester Pregnancy

    The concomitant phenomenon of a third trimester pregnancy with a significant degree of pelvic organ prolapse is extremely rare. We report on a patient with pelvic organ prolapse complicating third trimester pregnancy treated by concomitant cesarean hysterectomy and abdominal sacrocolpopexy. A 30-year-old woman,[…][ncbi.nlm.nih.gov]

    Missing: Percentage of Naive B Cells Increased
  • Rheumatoid Arthritis

    Follow-up laboratory analysis demonstrated a decrease in liver enzymes and also of the ANA-titer.[ncbi.nlm.nih.gov] In controls (Figure 1 B, Table 2 ), the percentage of naive and memory cells decreased and increased, respectively, with age.[bloodjournal.org] [ 40 ], which may be relevant to the function of n-3 PUFA on immunoglobulin A nephropathy.[doi.org]

  • Waldenstrom Macroglobulinemia

    Bing J et al. (1937) Reports of a third case of hyperglobulinemia with affection of the central nervous system on a toxi-infectious basis.[doi.org] Normal immunoglobulin synthesis is decreased, and the person is susceptible to infection, particularly bacterial pneumonia and septicemia.[healthcentral.com] Normal immunoglobulins are decreased in half of patients.[msdmanuals.com]

    Missing: Percentage of Naive B Cells Increased
  • Multiple Myeloma

    Serum concentrations of immunoglobulin G decreased and plasma cells in bone marrow decreased.[ncbi.nlm.nih.gov] The amount of normal immunoglobulins in the sample may be visibly decreased as well.[labtestsonline.org] Targeted therapy : Targeted therapy with proteasome inhibitors is given to decrease how much immunoglobulin M is in the blood and treat amyloidosis.[cancer.gov]

    Missing: Percentage of Naive B Cells Increased
  • Heavy Chain Disease

    […] hypermutation: implications for oncogene translocations and heavy chain disease. ( 9482908 ) Goossens T....KA1ppers R. 1998 45 A case of mu heavy-chain disease associated with hyperglobulinemia[malacards.org] Three subtypes are known based on the type of monoclonal immunoglobulin produced ie. alpha-heavy chain, gamma-heavy chain and mu-heavy chain disease in order of decreasing[bloodjournal.org] . : A case of mu heavy-chain disease associated with hyperglobulinemia, anemia, and a positive Coombs test. Ann Hematol 1998, 77:231–234.[link.springer.com]

    Missing: Percentage of Naive B Cells Increased
  • Chronic Lymphocytic Leukemia

    As CLL progresses, abnormal hematopoiesis results in pancitopenia and decreased immunoglobulin production, followed by nonspecific symptoms such as fatigue or malaise.[intechopen.com] As CLL progresses, abnormal hematopoiesis results in anemia, neutropenia, thrombocytopenia, and decreased immunoglobulin production.[merckmanuals.com] This disease interferes with the normal production of antibodies and immunoglobulins, so the body cannot properly fight infections.[cancer.unm.edu]

    Missing: Percentage of Naive B Cells Increased
  • Nephrotic Syndrome

    Proposed explanations for the increased infection risk include the following: Urinary immunoglobulin losses Edema fluid acting as a culture medium Protein deficiency Decreased[emedicine.com]

    Missing: Percentage of Naive B Cells Increased
  • Amyloidosis

    Amyloidosis - primary; Immunoglobulin light chain amyloidosis; Primary systemic amyloidosis Gertz MA, Buadi FK, Lacy MQ, Hayman SR.[medlineplus.gov] […] transthyretin-associated (ATTR) amyloidosis. 3-8 In AA amyloidosis, production of SAA can sometimes be decreased by treatment of the underlying inflammatory condition. 9[doi.org] To target residual bound SAP, anti SAP immunoglobulin-G (IgG) antibodies have been generated [ 55 ].[doi.org]

    Missing: Percentage of Naive B Cells Increased
  • Systemic Amyloidosis

    […] gammopathy, an abnormal serum free light-chain (sFLC) ratio, the fraction of bone marrow plasma cells bearing an aberrant phenotype, increased bone marrow plasma cells, decreased[doi.org] An MC response, defined as a 50% MC decrease, was observed in 77 patients (57%) and translated into a survival advantage ( P .007).[doi.org] […] levels of polyclonal immunoglobulin, and aneuploidy. 2 – 7 However, the proportion of MM that develops from a preexisting MGUS or SMM is unknown and remains an important[doi.org]

    Missing: Percentage of Naive B Cells Increased
  • Precursor-Cell Lymphoblastic Leukemia

    The malignant leukemic cells are non-functional and the precursor-B cells do not produce immunoglobulins.[lecturio.com] The decreased red blood cells lead to anemia and pallor, while the decreased normal white blood cells lead to severe recurrent infections.[lecturio.com]

    Missing: Percentage of Naive B Cells Increased

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