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1,344 Possible Causes for Hyperglobulinemia, Intermittent Jaundice, Uric Acid Increased

  • Sickle Cell Disease

    Jaundice Fatigue Swollen hands and feet The severity of these symptoms can vary significantly for each individual with the disease, according to the specific characteristics[] Each individual with SCD is unique, but the most common features are: Anemia (may cause fatigue and decreased endurance), reticulocytosis, and jaundice Intermittent acute[] Consequences of hemolysis may include chronic anemia, jaundice, predisposition to aplastic crisis, cholelithiasis, and delayed growth and sexual maturation.[]

  • Diabetes Mellitus

    […] lowering uric acid levels prevented the increase in mean arterial blood pressure ( 40 ).[] […] whereas uric acid (HR per 1 mmol/L increase, 2.05) and physical inactivity during leisure time (HR, 1.80) were associated with diabetes development in women only.[] However, the quantities of fructose contained in SSBs are far greater than those contained in these preloads. 70 Fructose can also increase blood uric acid concentrations.[]

    Missing: Intermittent Jaundice
  • Non-Hodgkin Lymphoma

    It is characterized by hyperglobulinemia, excess bence-jones proteins (free monoclonal immunoglobulin light chains) in the urine, skeletal destruction, bone pain, and fractures[] acid.[] acid and LDH are at increased risk of tumor lysis syndrome resulting in metabolic derangements such as hyperuricemia, hyperkalemia, hyperphosphatemia, hypocalcemia, and subsequent[]

    Missing: Intermittent Jaundice
  • Leukemia

    acid. 21 Immunosuppression from chemotherapy, hematopoietic stem cell transplantation, or the leukemia itself may increase the risk of serious infections.[] […] renal failure, and includes aggressive intravenous fluid administration plus allopurinol (Zyloprim) or rasburicase (Elitek), a recombinant urate oxidase that breaks down uric[]

    Missing: Intermittent Jaundice
  • Multiple Myeloma

    The increased number of growing cancerous cells can lead to the overproduction and excretion of uric acid in the urine, which can lead to kidney stones.[] acid levels may be elevated as a complication of multiple myeloma.[] People who have high levels of uric acid in the blood or widespread disease may benefit from allopurinol, a drug that blocks the body's production of uric acid.[]

    Missing: Intermittent Jaundice
  • Polycythemia Vera

    […] hematopoietic stem cells, characterized by increased blood volume, bone marrow hyperplasia, redness of the skin, and splenic enlargement. polycythemia vera polycythemia vera Hyperglobulinemia[] Increased uric acid Presence of the JAK2 mutation Hypercellular bone marrow 5.[] Severe continuous small joint pain Patients will present with symptoms of gout as a result of increased uric acid production. Gout mainly affects big toe.[]

    Missing: Intermittent Jaundice
  • Myeloproliferative Disease

    Furthermore, ruxolitinib also decreased plasma levels of N-terminal pro-brain natriuretic peptide, von Willebrand antigen, ristocetin-cofactor activity and uric acid, and[] increased nitric oxide levels.[]

    Missing: Intermittent Jaundice
  • Acute Myelocytic Leukemia

    Joint Pain Joint pain occurs due to the presence of increased deposition of uric acid in the joints resulting in gout .[] Hyperleukocytosis also increases the odds of spontaneous TLS and the number of blasts contributing to the uric acid load.[] acid; in late stages, leukocytes infiltrate the kidneys - Enlarged organs (spleen,liver)- Caused by increased number of white blood cells accumulating within liver and spleen[]

    Missing: Intermittent Jaundice
  • Sarcoidosis

    Radiographics. 2018 Jul-Aug;38(4):1180-1200. doi: 10.1148/rg.2018170157. Author information 1 From the Department of Radiology, University of Texas MD Anderson Cancer Center, Pickens Academic Tower, 1400 Pressler St, Unit 1473, Houston, TX 77030-4009 (D.G.); Department of Radiology, Mayo Clinic Arizona,[…][]

    Missing: Intermittent Jaundice
  • Waldenstrom Macroglobulinemia

    Bing J et al. (1937) Reports of a third case of hyperglobulinemia with affection of the central nervous system on a toxi-infectious basis.[] Incipient myelomatosis or ‘essential’ hyperglobulinemia with fibrinogenopenia a new syndrome?. Acta Med Scand, CXVII (1944), pp. 217-246 [4] R.E. Cooke, R.M.[] Waldenström J: Incipient myelomatosis or “essential” hyperglobulinemia with fibrinogenopenia: a new syndrome ? Acta Med Scand 1944, 117 :216–222.[]

    Missing: Intermittent Jaundice

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