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278 Possible Causes for Hypergranulosis

  • Actinic Lichen Planus

    In the epidermis, there is wedge-shaped hypergranulosis, compact orthokeratosis, and apoptotic keratinocytes along the basal layer.[escholarship.org] The histological examination (Fig. 2) showed compact, wedge-shaped hypergranulosis, elongated epidermal crests, coarse basal cell vacuolization and Civatte bodies.[ejpd.com] Arrows: basal layer colliquation (green), melanophages (orange), hyperkeratosis (red), wedge hypergranulosis (blue) FIGURE 4 Strip Inflammatory infiltrate (circle), pigmentary[scielo.br]

  • Palmoplantar Keratosis

    Histological findings include hyperkeratosis, hypergranulosis, and acanthosis.[intechopen.com] —There is epidermal hyperplasia with hypergranulosis, a thin layer of parakeratosis, and overlying orthokeratosis.[dermatology.cdlib.org] Histopathologic examination revealed orthohyperkeratosis within focal clavus‐like depressions of the epidermis and prominent hypergranulosis.[dx.doi.org]

  • Verruca Vulgaris

    Hypergranulosis (thicker stratum granulosum). Papillomatous hyperplasia : Rete ridge lengthening ( 7-10x normal) and thickening.[librepathology.org] […] types 2 and 4; the lesions are of variable duration, eventually undergoing spontaneous regression, and are both exophytic and endophytic, with hyperkeratosis, parakeratosis, hypergranulosis[medical-dictionary.thefreedictionary.com] LM papillomatous hyperplasia (rete ridges long & curve inward), hyperkeratosis, hypergranulosis, large blood vessels at the dermal-epidermal junction, /-viral changes - perinuclear[librepathology.org]

  • Bullous Lichen Planus

    Histopathological examination with hematoxylene and eosin stain revealed parakeratosis with hypergranulosis and mild basal cell hyperplasia.[idoj.in] The histological examination of the papular lesion showed hypergranulosis, degeneration of the basal layer, lymphocytic band infiltrate in the superficial dermis (Fig. 3 and[ejpd.com] Histopathology from a bullous lesion, (A) with subepidermal clefting (H&E, 10) and (B) with hypergranulosis and sawtooth-like acanthosis (H&E, 40).[ncbi.nlm.nih.gov]

  • Epidermodysplasia Verruciformis

    The histopathologic features of EV consist of papillated epidermal hyperplasia with hypergranulosis and a distinct bluish-gray color in the large human papillomavirus-infected[ncbi.nlm.nih.gov] Areas of epidermis showed compact orthokeratosis, coarse hypergranulosis, and keratinocytes with abundant steel-blue-gray cytoplasm, indicative of viral cytopathic changes[ncbi.nlm.nih.gov] Histological analysis of the wart lesions showed epidermis with hyperkeratosis, regular acanthosis, hypergranulosis, and cells with abundant basophilic cytoplasm.[ncbi.nlm.nih.gov]

  • Diffuse Palmoplantar Keratoderma

    Histopathological examination of the skin biopsy taken from the patient’s sole revealed orthokeratotic hyperkeratosis, hypergranulosis and acanthosis without epidermolysis[indianpediatrics.net] Histologic findings include hyperkeratosis, hypergranulosis, and acanthosis.[emedicine.medscape.com] , and acanthosis (PPK) Birth-Adolescence Yes No H H Compact hyperkeratotsis, hypergranulosis, and acanthosis, subepidermal vessels were dilated, mild mononuclear cell infiltrate[dermatologyadvisor.com]

  • Pityriasis Rubra Pilaris

    Occasionally, mild spongiosis with scattered intraepidermal lymphocytes In early lesions, parakeratosis is poorly developed and lamellar ortho hyperkeratosis predominates; hypergranulosis[pathologyoutlines.com] […] histologic) description Biopsy from non-follicular lesion consists of alternating orthokeratosis and parakeratosis in both vertical and horizontal directions Focal or confluent hypergranulosis[pathologyoutlines.com]

  • Papillon Lefevre Disease

    Skin biopsy shows hyperkeratosis with focal parakeratosis, moderate perivascular infiltration, hypergranulosis, and acanthosis.[rarediseases.info.nih.gov] Histhopathologic examination of the hyperkeratotic plantar skin revealed hyperkeratosis, hypergranulosis, acanthosis and a dense perivascular lymphocytic infiltration.[scitechnol.com]

  • Lichen Planus

    They differ from those of cutaneous disease in several respects, including the presence of parakeratosis, epithelial atrophy, and lack of hypergranulosis.[ncbi.nlm.nih.gov] LP has an associated set of characteristic histopathologic findings which include hyperkeratosis, vacuolization of the basal layer, Civatte bodies, wedge-shaped hypergranulosis[ncbi.nlm.nih.gov] Biopsy of a lesion revealed hyperkeratosis, wedge-shaped hypergranulosis, sawtooth rete pegs, and bandlike lymphocytic inflammation — findings confirming the diagnosis of[nejm.org]

  • Lichen Simplex Chronicus

    Histologically, the lesions were characterized by moderate to marked hyperorthokeratosis and wedge-shaped hypergranulosis.[ncbi.nlm.nih.gov] As a consequence, there are compact orthokeratosis, hypergranulosis, uneven psoriasiform acanthosis, and coarse bundles of collagen arranged in vertical streaks in a thickened[derm101.com] Histologic Features: Prominent irregular acanthosis (the rete ridges are of varying length) Hyperkeratosis, sometimes with focal parakeratosis, and hypergranulosis Vertically[dermpedia.org]

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