Create issue ticket

593 Possible Causes for Hyperintensities in the Globus Pallidus (T2-Weighted), Lower Motor Neuron Signs - Later, Pyramidal Tract Signs

Did you mean: Hyperintensities in the Globus Pallidus (T2-Weighted, Lower Motor Neuron Signs - Later, Pyramidal Tract Signs

  • Mitochondrial Membrane Protein-Associated Neurodegeneration

    tract signs with heavy iron accumulation at the globus pallidum and the substantia nigra [ 1, 2 ].[omicsonline.org] Key Diagnostic Features: Once the parkinsonian symptoms appear, brain MRI shows hypointensity in the region of substantia nigra (SN) and globus pallidus (GP) on T2-weighted[ajnr.org] Early upper motor neuron signs (pyramidal signs, e.g. spasticity) are constant findings and are later followed by signs of lower motor neuron dysfunction (deep tendon reflex[malacards.org]

  • Hallervorden-Spatz Syndrome

    Table-1: Diagnostic features of Hallervorden spatz disease [11] Obligate Features Collaborate Features Exclusion Features Onset during first two decades Pyramidal tract signs[medresearch.in] This virtually pathognomonic radiographic abnormality, called the eye-of-the-tiger sign, comprises hyperintensities within a hypointense medial globus pallidus on T2-weighted[ncbi.nlm.nih.gov] […] pattern of hyperintensity within the hypointense medial globus pallidus.[ncbi.nlm.nih.gov]

    Missing: Lower Motor Neuron Signs - Later
  • Neurodegeneration with Brain Iron Accumulation

    . • Begins in childhood • Profound dystonia, dysarthria, spasticity and pyramidal tract signs • Pigmentary retinopathy, leading to night blindness and visual field constriction[slideshare.net] Even before the globus pallidus hypointensity developed, patients with mutations could be distinguished by the presence of isolated globus pallidus hyperintensity on T2-weighted[ncbi.nlm.nih.gov] Here, we report three C19orf12-mutant patients from two families presenting with predominant upper and lower motor neuron dysfunction mimicking amyotrophic lateral sclerosis[ncbi.nlm.nih.gov]

  • Upper Motor Neuron Disease

    Increased deep tendon reflex (DTR) Pronator drift [3] Corticospinal/pyramidal tract [ edit ] These are the neural tracts which descend in the ventral horn of the spinal cord[en.wikipedia.org] *Mixture of upper and lower motor neuron signs* It never affects sensation/cerebellum/vision Types of MND: Amyotrophic lateral sclerosis: Mixed upper and lower motor neurone[medicaleducationleeds.com] The muscles with lower motor neuron sign(weakness) usually relate with abnormal MEPs reponses.[e-acn.org]

    Missing: Hyperintensities in the Globus Pallidus (T2-Weighted)
  • Pallidopyramidal Syndrome

    […] of early-onset, progressive parkinsonism with pyramidal tract signs has been known as pallido-pyramidal or parkinsonian-pyramidal syndrome since the first description by[moh-it.pure.elsevier.com] The patients also showed clinical and electrophysiological signs of upper and/or lower motor neuron degeneration.[karger.com] Abstract Background: The combination of early-onset, progressive parkinsonism with pyramidal tract signs has been known as pallido-pyramidal or parkinsonian-pyramidal syndrome[n.neurology.org]

    Missing: Hyperintensities in the Globus Pallidus (T2-Weighted)
  • Amyotrophic Lateral Sclerosis Type 1

    neuron disease variant with only lower or upper motor neuron signs Primary lateral sclerosis (upper motor neuron only) ?[neuromuscular.wustl.edu] El Escorial criteria for the diagnosis of amyotrophic lateral sclerosis 7 : it requires the presence of signs of lower motor neuron (LMN) degeneration by clinical, electrophysiological[radiopaedia.org] motor neuron signs in 2 regions and Upper motor neuron signs in a region rostral to the lower motor neuron signs Variant syndromes Primary muscular atrophy (PMA) : Lower[neuromuscular.wustl.edu]

    Missing: Hyperintensities in the Globus Pallidus (T2-Weighted)
  • Amyotrophic Lateral Sclerosis

    Autosomal dominant juvenile amyotrophic lateral sclerosis and distal hereditary motor neuronopathy with pyramidal tract signs: synonyms for the same disorder?[ncbi.nlm.nih.gov] It is one of many motor neuron diseases, but what makes it stand out is that it presents with both upper and lower motor neuron signs.[symptoma.com] Signs of pyramid release are not always marked and, only recently, non-invasive tests to reveal cortical spinal tract commitment have been incorporated into the medical practice[doi.org]

    Missing: Hyperintensities in the Globus Pallidus (T2-Weighted)
  • Pyramidal Tract Lesion

    Babinski sign in absence of Pyramidal Tract Lesion can occur in physiological and pathological conditions Physiological causes of Babinski sign in absence of Pyramidal Tract[notes.medicosnotes.com] Lower motor neuron signs are pyramidal not extrapyramidal.[forums.studentdoctor.net] Neurological examination revealed bilateral pyramidal-tract signs, and paresis of the right arm.[em-consulte.com]

    Missing: Hyperintensities in the Globus Pallidus (T2-Weighted)
  • Binswanger Disease

    The bilateral cerebral white matter and globus pallidus appeared hyperintense on T2-weighted imaging (Figures 5 and 6). 5) Figure 5. CO poisoning(FLAIR image) Figure 6.[plaza.umin.ac.jp] The hippocampus, cerebral white matter, basal ganglion, and other areas appear hyperintense on T2-weighted imaging. CO poisoning: Delayed diffuse demyelination.[plaza.umin.ac.jp] No contrast enhancement effect is evident. (4) Poisoning and metabolic disorders Hypoxic encephalopathy: Diffusion-weighted imaging is useful for diagnosis.[plaza.umin.ac.jp]

    Missing: Lower Motor Neuron Signs - Later
  • Central Pontine Myelinolysis

    In (CPM), the initial signs include dysarthria and dysphagia (secondary to corticobulbar fiber involvement), and flaccid quadriparesis (from pyramidal tract involvement) which[omicsonline.org] […] of Globus Pallidus (broad arrow), suggestive of Extrapontine myelinolysis.[ipfs.io] weighted magnetic resonance scan image showing bilaterally symmetrical hyperintensities in caudate nucleus (small, thin arrow), putamen (long arrow), with sparing of globus[en.wikipedia.org]

    Missing: Lower Motor Neuron Signs - Later