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11 Possible Causes for Hyperintensities in the Globus Pallidus (T2-Weighted), Muscle Twitch, Pyramidal Tract Signs

Did you mean: Hyperintensities in the Globus Pallidus (T2-Weighted, Muscle Twitch, Pyramidal Tract Signs

  • Hallervorden-Spatz Syndrome

    Table-1: Diagnostic features of Hallervorden spatz disease [11] Obligate Features Collaborate Features Exclusion Features Onset during first two decades Pyramidal tract signs[] This virtually pathognomonic radiographic abnormality, called the eye-of-the-tiger sign, comprises hyperintensities within a hypointense medial globus pallidus on T2-weighted[] They may experience involuntary muscle contractions (dystonia) of the head and neck, resulting in repetitive movements and contortions.[]

  • Binswanger Disease

    The bilateral cerebral white matter and globus pallidus appeared hyperintense on T2-weighted imaging (Figures 5 and 6). 5) Figure 5. CO poisoning(FLAIR image) Figure 6.[] […] in a visible twitch of all the muscle fibers it contacts; indicative of denervation festination an involuntary tendency to take short accelerating steps in walking that can[] The hippocampus, cerebral white matter, basal ganglion, and other areas appear hyperintense on T2-weighted imaging. CO poisoning: Delayed diffuse demyelination.[]

  • Wilson Disease

    In Wilson disease, an abnormal striatum depicted on MR images correlated with pseudoparkinsonian signs, an abnormal dentatothalamic tract correlated with cerebellar signs,[] On T1W images, these lesions are normal to hypointense but hyperintense lesions especially in globus pallidus may also be seen [ 2 ].[] twitching, tremor and contractions.[]

  • Neurodegeneration with Brain Iron Accumulation

    . • Begins in childhood • Profound dystonia, dysarthria, spasticity and pyramidal tract signs • Pigmentary retinopathy, leading to night blindness and visual field constriction[] Even before the globus pallidus hypointensity developed, patients with mutations could be distinguished by the presence of isolated globus pallidus hyperintensity on T2-weighted[] muscle twitches) Muscle weakness Stiffness of limbs Dystonia: Involuntary muscle contractions that cause repetitive movements or distorted postures Dysphagia (difficulty in[]

  • Creutzfeldt Jakob Disease

    Other neurologic findings may include cerebellar signs, pyramidal tract signs, extrapyramidal signs, corticla visual defects, abnormal extraocular movements, lower motor neuron[] Extrapontine myelinolysis manifests predominantly as areas of bilateral FLAIR /T2-weighted imaging hyperintensity in the globus pallidus, putamen, and thalamus, which are[] Startling may trigger muscle twitching. The muscles that control breathing and coughing are usually impaired, increasing the risk of pneumonia.[]

  • Beta-Propeller Protein-Associated Neurodegeneration

    . • Ataxia follows, and dysarthria and progressive spastic quadriparesis with pyramidal tract signs develop.[] Key Diagnostic Features: Once the parkinsonian symptoms appear, brain MRI shows hypointensity in the region of substantia nigra (SN) and globus pallidus (GP) on T2-weighted[] […] tone (atonic seizures), involuntary muscle twitches (myoclonic seizures), or more pronounced movements called epileptic spasms.[]

  • McLeod Neuroacanthocytosis Syndrome

    Rarely, pyramidal tract signs; and d. Rarely, cranial nerve involvement [ Kane & Havel 1995, Tarugi & Averna 2011 ]. 3.[] […] pattern of hyperintensity within the hypointense medial globus pallidus.[] […] in muscle activity such as twitching or hyperactivity.[]

  • Axonal Neuropathy

    tract signs. 1 Patients become wheelchair bound in the second decade and eventually bedridden with severe polyneuropathy, ataxia and dementia.[] An exam may show: Decreased feeling (may affect touch, pain, vibration, or position sensation) Diminished reflexes (most commonly the ankle) Muscle atrophy Muscle twitches[] hyperintensity is also seen in the pons, middle cerebellar peduncles, and bilateral cerebellar white matter. 3 Posteromedial thalamus may also be affected. 3 The globus pallidus[]

  • Basal Ganglia Mass Lesion

    Neurologic examination demonstrated a right hemiparesis with hypereflexia, bilateral pyramidal tract signs, right facial nerve palsy, dysarthria, dystonia that was more prominent[] Tics Tics are fleeting, purposeless actions that may be simple (appearing as a muscle twitch) or complex (which may involve more repetitive behavior.[] These spikes cause the muscle fibers that are part of that neuron’s motor unit to fire, resulting in a visible twitch (called a fasciculation) of the affected muscle (Figure[]

  • Primary Torsion Dystonia 6

    […] of a pyramidal tract syndrome, and dystonic movements occur in disorders of the basal ganglia (e.g.[] […] signal on T2-weighted scans.[] The disorder usually first impacts muscles of the head and neck, causing problems with speaking (dysarthria) and eating (dysphagia).[]

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