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17 Possible Causes for Hyperintensities in the Globus Pallidus (T2-Weighted), Pediatric Disorder, Pyramidal Tract Signs

Did you mean: Hyperintensities in the Globus Pallidus (T2-Weighted, Pediatric Disorder, Pyramidal Tract Signs

  • Hallervorden-Spatz Syndrome

    Table-1: Diagnostic features of Hallervorden spatz disease [11] Obligate Features Collaborate Features Exclusion Features Onset during first two decades Pyramidal tract signs[medresearch.in] This virtually pathognomonic radiographic abnormality, called the eye-of-the-tiger sign, comprises hyperintensities within a hypointense medial globus pallidus on T2-weighted[ncbi.nlm.nih.gov] […] treatments and interventions Covers neurological, neuropsychiatric, and neuromedical disorders across the lifespan (pediatric, adult, and geriatric populations) Includes[books.google.com]

  • Binswanger Disease

    The bilateral cerebral white matter and globus pallidus appeared hyperintense on T2-weighted imaging (Figures 5 and 6). 5) Figure 5. CO poisoning(FLAIR image) Figure 6.[plaza.umin.ac.jp] […] treatments and interventions Covers neurological, neuropsychiatric, and neuromedical disorders across the lifespan (pediatric, adult, and geriatric populations) Includes[books.google.de] The hippocampus, cerebral white matter, basal ganglion, and other areas appear hyperintense on T2-weighted imaging. CO poisoning: Delayed diffuse demyelination.[plaza.umin.ac.jp]

  • Central Pontine Myelinolysis

    In (CPM), the initial signs include dysarthria and dysphagia (secondary to corticobulbar fiber involvement), and flaccid quadriparesis (from pyramidal tract involvement) which[omicsonline.org] […] of Globus Pallidus (broad arrow), suggestive of Extrapontine myelinolysis.[ipfs.io] Carlos Ayus, Preventing neurological complications from dysnatremias in children, Pediatric Nephrology, 10.1007/s00467-005-1933-6, 20, 12, (1687-1700), (2005).[oadoi.org]

  • Wilson Disease

    In Wilson disease, an abnormal striatum depicted on MR images correlated with pseudoparkinsonian signs, an abnormal dentatothalamic tract correlated with cerebellar signs,[pubs.rsna.org] On T1W images, these lesions are normal to hypointense but hyperintense lesions especially in globus pallidus may also be seen [ 2 ].[omcr.oxfordjournals.org] disorders Genotype–phenotype correlation Summary Chapter 13: Other organ involvement and clinical aspects of Wilson disease Karolina Dziezyc, Tomasz Litwin and Anna Czlonkowska[elsevier.com]

  • Neurodegeneration with Brain Iron Accumulation

    . • Begins in childhood • Profound dystonia, dysarthria, spasticity and pyramidal tract signs • Pigmentary retinopathy, leading to night blindness and visual field constriction[slideshare.net] Even before the globus pallidus hypointensity developed, patients with mutations could be distinguished by the presence of isolated globus pallidus hyperintensity on T2-weighted[ncbi.nlm.nih.gov] The presentation of NBIA overlaps with the more common adult movement disorders and pediatric neurometabolic conditions, and a high index of suspicion is required to make[ncbi.nlm.nih.gov]

  • Alexander Disease

    We report a case of genetically confirmed adult-onset AD with palatal myoclonus, pyramidal tract signs, cerebellar signs, and marked atrophy of the medulla oblongata and spinal[ncbi.nlm.nih.gov] In addition, there are symmetrical hyperintensity signals in the posterior part of the globus pallidus on T2-weighted images in the two symptomatic patients, which are rarely[ncbi.nlm.nih.gov] Disease Focus: Neurological Disorders Pediatrics Grant Application Details Application Title: Modeling Alexander disease using patient-specific induced pluripotent stem cells[cirm.ca.gov]

  • Infantile Dystonia - Parkinsonism

    signs.[medical-dictionary.thefreedictionary.com] […] signal on T2-weighted scans.[e-jmd.org] Kruer * * Sanford Children's Pediatric Movement Disorders Clinic, Division of Pediatric Neurology, Sanford Children’s Specialty Clinic, Sioux Falls, SD.[pedsinreview.aappublications.org]

  • Neuroferritinopathy

    tract signs, and psychiatric symptoms.[ncbi.nlm.nih.gov] pallidus, on T2-weighted images.[emedicine.medscape.com] Semin Pediatr Neurol. 2006 Sep;13(3):176-81. Burn J. Neuroferritinopathy: iron in the brain.[ghr.nlm.nih.gov]

  • McLeod Neuroacanthocytosis Syndrome

    Rarely, pyramidal tract signs; and d. Rarely, cranial nerve involvement [ Kane & Havel 1995, Tarugi & Averna 2011 ]. 3.[ncbi.nlm.nih.gov] […] pattern of hyperintensity within the hypointense medial globus pallidus.[scienceopen.com] Michael E Miller, Functional Leukocyte Disorders, Pediatric Annals, 10.3928/0090-4481-19790601-05, 8, 6, (10-24), (1979).[doi.org]

  • Mitochondrial Membrane Protein-Associated Neurodegeneration

    tract signs with heavy iron accumulation at the globus pallidum and the substantia nigra [ 1 , 2 ].[omicsonline.org] Key Diagnostic Features: Once the parkinsonian symptoms appear, brain MRI shows hypointensity in the region of substantia nigra (SN) and globus pallidus (GP) on T2-weighted[ajnr.org] J Pediatr Neurosci 2016;11:288-9 Dear Sir, Neurodegeneration with brain iron accumulation (NBIA) is a group of genetic disorders with a progressive extrapyramidal syndrome[pediatricneurosciences.com]