Create issue ticket

19 Possible Causes for Hyperintensities in the Globus Pallidus (T2-Weighted), Pyramidal Tract Signs

Did you mean: Hyperintensities in the Globus Pallidus (T2-Weighted, Pyramidal Tract Signs

  • Hallervorden-Spatz Syndrome

    Table-1: Diagnostic features of Hallervorden spatz disease [11] Obligate Features Collaborate Features Exclusion Features Onset during first two decades Pyramidal tract signs[medresearch.in] This virtually pathognomonic radiographic abnormality, called the eye-of-the-tiger sign, comprises hyperintensities within a hypointense medial globus pallidus on T2-weighted[ncbi.nlm.nih.gov] […] pattern of hyperintensity within the hypointense medial globus pallidus.[ncbi.nlm.nih.gov]

  • Binswanger Disease

    The bilateral cerebral white matter and globus pallidus appeared hyperintense on T2-weighted imaging (Figures 5 and 6). 5) Figure 5. CO poisoning(FLAIR image) Figure 6.[plaza.umin.ac.jp] The hippocampus, cerebral white matter, basal ganglion, and other areas appear hyperintense on T2-weighted imaging. CO poisoning: Delayed diffuse demyelination.[plaza.umin.ac.jp] No contrast enhancement effect is evident. (4) Poisoning and metabolic disorders Hypoxic encephalopathy: Diffusion-weighted imaging is useful for diagnosis.[plaza.umin.ac.jp]

  • Central Pontine Myelinolysis

    In (CPM), the initial signs include dysarthria and dysphagia (secondary to corticobulbar fiber involvement), and flaccid quadriparesis (from pyramidal tract involvement) which[omicsonline.org] […] of Globus Pallidus (broad arrow), suggestive of Extrapontine myelinolysis.[ipfs.io] weighted magnetic resonance scan image showing bilaterally symmetrical hyperintensities in caudate nucleus (small, thin arrow), putamen (long arrow), with sparing of globus[en.wikipedia.org]

  • Neurodegeneration with Brain Iron Accumulation

    . • Begins in childhood • Profound dystonia, dysarthria, spasticity and pyramidal tract signs • Pigmentary retinopathy, leading to night blindness and visual field constriction[slideshare.net] Even before the globus pallidus hypointensity developed, patients with mutations could be distinguished by the presence of isolated globus pallidus hyperintensity on T2-weighted[ncbi.nlm.nih.gov] Ataxia follows, and dysarthria and progressive spastic quadriparesis with pyramidal tract signs develop.[ajnr.org]

  • Alexander Disease

    We report a case of genetically confirmed adult-onset AD with palatal myoclonus, pyramidal tract signs, cerebellar signs, and marked atrophy of the medulla oblongata and spinal[ncbi.nlm.nih.gov] In addition, there are symmetrical hyperintensity signals in the posterior part of the globus pallidus on T2-weighted images in the two symptomatic patients, which are rarely[ncbi.nlm.nih.gov] Adults may present with bulbar/pseudobulbar signs, pyramidal tract signs, cerebellar signs, dysautonomia, sleep disturbance, gait disturbance, hemiparesis/hemiplegia or quadriparesis[ncbi.nlm.nih.gov]

  • Neuroferritinopathy

    tract signs, and psychiatric symptoms.[ncbi.nlm.nih.gov] pallidus, on T2-weighted images.[emedicine.medscape.com] Axial FLAIR- (A) and GRE T2-weighted (B) MRI discloses ‘ eye-of- the-tiger ’ sign, defined as a medial area of hyperintense signal within an hypointense signal in globus pallidus[scielo.br]

  • McLeod Neuroacanthocytosis Syndrome

    Rarely, pyramidal tract signs; and d. Rarely, cranial nerve involvement [ Kane & Havel 1995, Tarugi & Averna 2011 ]. 3.[ncbi.nlm.nih.gov] […] pattern of hyperintensity within the hypointense medial globus pallidus.[scienceopen.com] In all patients with pantothenate kinase-associated neurodegeneration, whether classic or atypical, T2-weighted magnetic resonance imaging (MRI) of the brain showed a specific[scienceopen.com]

  • Infantile Dystonia - Parkinsonism

    signs.[medical-dictionary.thefreedictionary.com] […] signal on T2-weighted scans.[e-jmd.org] Pyramidal tract signs also emerged in the course of the disease in two patients.[ncbi.nlm.nih.gov]

  • Endemic Cretinism

    The 10 others were clinically euthyroid and had deaf-mutism and/or pyramidal tract dysfunction (neurological cretinism).[ncbi.nlm.nih.gov] All show an apparent magnetic resonance imaging abnormality in the globus pallidus and substantia nigra, with hyperintensity on T1-weighted images and hypointensity on T2-[ncbi.nlm.nih.gov] Nine of them exhibited clinical and biochemical signs of hypothyroidism (myxedematous cretins).[ncbi.nlm.nih.gov]

  • Mitochondrial Membrane Protein-Associated Neurodegeneration

    tract signs with heavy iron accumulation at the globus pallidum and the substantia nigra [ 1 , 2 ].[omicsonline.org] Key Diagnostic Features: Once the parkinsonian symptoms appear, brain MRI shows hypointensity in the region of substantia nigra (SN) and globus pallidus (GP) on T2-weighted[ajnr.org] pallidus, on T2-weighted images.[emedicine.medscape.com]

Further symptoms