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19 Possible Causes for Hyperintensities in the Globus Pallidus (T2-Weighted), Pyramidal Tract Signs, Seizure

Did you mean: Hyperintensities in the Globus Pallidus (T2-Weighted, Pyramidal Tract Signs, Seizure

  • Binswanger Disease

    The bilateral cerebral white matter and globus pallidus appeared hyperintense on T2-weighted imaging (Figures 5 and 6). 5) Figure 5. CO poisoning(FLAIR image) Figure 6.[plaza.umin.ac.jp] Clinton suffers from “Dementia, Seizures and Black-outs.” In fact, the Doctor made note that Clinton’s conditions are “considerably worse” than in 2013.[globalresearch.ca] Abnormal electrical disturbances in the brain may cause seizures. Binswanger's symptoms may be elusive in both appearance and degree.[encyclopedia.com]

  • Hallervorden-Spatz Syndrome

    Table-1: Diagnostic features of Hallervorden spatz disease [11] Obligate Features Collaborate Features Exclusion Features Onset during first two decades Pyramidal tract signs[medresearch.in] The patient presented with a slowly progressive illness with seizures, extrapyramidal symptoms, cerebellar ataxia, dementia, spasticity, myoclonic movements and a severe demyelinating[ncbi.nlm.nih.gov] This virtually pathognomonic radiographic abnormality, called the eye-of-the-tiger sign, comprises hyperintensities within a hypointense medial globus pallidus on T2-weighted[ncbi.nlm.nih.gov]

  • Central Pontine Myelinolysis

    In (CPM), the initial signs include dysarthria and dysphagia (secondary to corticobulbar fiber involvement), and flaccid quadriparesis (from pyramidal tract involvement) which[omicsonline.org] Clinical presentation of CPEPM is heterogeneous and can even include seizures.[dx.doi.org] […] of Globus Pallidus (broad arrow), suggestive of Extrapontine myelinolysis.[ipfs.io]

  • Neurodegeneration with Brain Iron Accumulation

    . • Begins in childhood • Profound dystonia, dysarthria, spasticity and pyramidal tract signs • Pigmentary retinopathy, leading to night blindness and visual field constriction[slideshare.net] Even before the globus pallidus hypointensity developed, patients with mutations could be distinguished by the presence of isolated globus pallidus hyperintensity on T2-weighted[ncbi.nlm.nih.gov] […] abnormalities and cognitive decline… BPAN BPAN (Beta-propeller Protein-associated Neurodegeneration) is an NBIA disorder that is characterized by childhood developmental delay and seizures[nbiacure.org]

  • Alexander Disease

    We report a case of genetically confirmed adult-onset AD with palatal myoclonus, pyramidal tract signs, cerebellar signs, and marked atrophy of the medulla oblongata and spinal[ncbi.nlm.nih.gov] Alexander disease is a leukoencephalopathy that usually presents during infancy with developmental delay, macrocephaly and seizures.[ncbi.nlm.nih.gov] In addition, there are symmetrical hyperintensity signals in the posterior part of the globus pallidus on T2-weighted images in the two symptomatic patients, which are rarely[ncbi.nlm.nih.gov]

  • McLeod Neuroacanthocytosis Syndrome

    Rarely, pyramidal tract signs; and d. Rarely, cranial nerve involvement [ Kane & Havel 1995, Tarugi & Averna 2011 ]. 3.[ncbi.nlm.nih.gov] […] pattern of hyperintensity within the hypointense medial globus pallidus.[scienceopen.com] Findings not observed in RH are: progressive biopsy-proven dilative cardiomyopathy, grand mal seizures, psychotic episodes, cognitive impairment and chorea as the most prominent[hum-molgen.org]

  • Creutzfeldt Jakob Disease

    Other neurologic findings may include cerebellar signs, pyramidal tract signs, extrapyramidal signs, corticla visual defects, abnormal extraocular movements, lower motor neuron[library.med.utah.edu] Seizures are known to occur in Creutzfeldt-Jakob disease (CJD).[ncbi.nlm.nih.gov] Extrapontine myelinolysis manifests predominantly as areas of bilateral FLAIR /T2-weighted imaging hyperintensity in the globus pallidus, putamen, and thalamus, which are[doi.org]

  • Wilson Disease

    In Wilson disease, an abnormal striatum depicted on MR images correlated with pseudoparkinsonian signs, an abnormal dentatothalamic tract correlated with cerebellar signs,[pubs.rsna.org] His WD was in a state of remission when he developed the seizure disorder. On endoscopic cyst fenestration, he was relieved of the seizure.[ncbi.nlm.nih.gov] On T1W images, these lesions are normal to hypointense but hyperintense lesions especially in globus pallidus may also be seen [ 2 ].[omcr.oxfordjournals.org]

  • Beta-Propeller Protein-Associated Neurodegeneration

    . • Ataxia follows, and dysarthria and progressive spastic quadriparesis with pyramidal tract signs develop.[slideshare.net] Affected individuals can also experience generalized tonic-clonic seizures (also known as grand mal seizures).[elbiruniblogspotcom.blogspot.no] Key Diagnostic Features: Once the parkinsonian symptoms appear, brain MRI shows hypointensity in the region of substantia nigra (SN) and globus pallidus (GP) on T2-weighted[ajnr.org]

  • Mitochondrial Membrane Protein-Associated Neurodegeneration

    tract signs with heavy iron accumulation at the globus pallidum and the substantia nigra [ 1 , 2 ].[omicsonline.org] Key Diagnostic Features: Once the parkinsonian symptoms appear, brain MRI shows hypointensity in the region of substantia nigra (SN) and globus pallidus (GP) on T2-weighted[ajnr.org] pallidus, on T2-weighted images.[emedicine.medscape.com]

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